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Summary of Contents for TSE PhenoMaster
- Page 1 Sophisticated Life Science Research Instrumentation PhenoMaster Hardware Operating Instructions Core Modules © www.TSE-Systems.com Info@TSE-Systems.com...
- Page 2 These operating instructions, including all parts thereof, are protected by copyright. Any infringement of the copyright laws without the written agreement of the TSE Systems GmbH is illegal and subject to due penalty at law. This applies in particular to their reproduction, processing, translation, microfilming as well as to their storage and processing in electronic systems.
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Page 3: Table Of Contents
10.2.1.2. Metallic Cage Lid ......................37 10.2.1.3. Cage Body (Home Cage) ....................37 10.3. Control Unit, PC, Monitor, and Keyboard ............... 38 10.4. Cable ..........................39 10.5. Rack ..........................39 Appendix A. Example configurations B. Cage body specifications info@TSE-Systems.com www.TSE-Systems.com... - Page 4 PhenoMaster | Hardware Operating Instructions List of Figures Fig. 1 ActiMot2 result parameters (table data, binary data) ..............5 Fig. 2 Calorimetry result parameters ....................6 Fig. 3 Hardware layout - Rod nipple....................14 Fig. 4 Positioning of O-ring (valve rod) ..................... 14 Fig.
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Page 5: Introduction
Service. The TSE system - a modular animal research platform - is designed to measure locomotor activity, metabolic performance, drinking and feeding behavior, and wheel activity of small laboratory animals during an experiment. The use of the different functional features according to the investigator`s requirements is possible. -
Page 6: Fig. 2 Calorimetry Result Parameters
PhenoMaster | Hardware Operating Instructions The operator can define a part of the sensors as the 'center'. This allows the measurement area to be adapted to suit animal cages with different sizes as well as the definition of two different measuring ranges (central and peripheral). - Page 7 A voluntary wheel can be included in the system in order to obtain further activity parameters. The voluntary wheel can be used to measure the spontaneous activity of the test animal. The number of turns that the wheel makes clockwise or counterclockwise will be registered. info@TSE-Systems.com www.TSE-Systems.com...
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Page 8: Instructions For Safe Operation
Service for your own safety. For contact data, please see last page. 2.2. Warranty TSE Systems warrant the operational safety and the operability of the system only under the condition that… • …the system is operated exclusively in accordance with its intended purpose - taking particular notice of the safety information - and as described in these operating instructions and is properly serviced and maintained;... -
Page 9: Notes For The User
• Any repairs to the system must be performed by members of the Technical Service of TSE Systems only, or by suitably trained and authorized expert personnel. Test run We recommend to perform a test run before the system is used for the first time in order to familiarize yourself with its operation and to make the necessary settings for the particular series of experiments. -
Page 10: Warnings And Labels On The System
Is used for application hints and useful information. 2.4.2. Warnings and Labels on the System In this section the warning information given on the components of the PhenoMaster system is explained. The warnings on the components correspond to those in these instructions. info@TSE-Systems.com... -
Page 11: Conformity
2.5.1. Proper Use The TSE PhenoMaster is a system, which can be used to determine the metabolic performance, the animal activity via sensor frames or infrared sensor(s), the drinking & feeding behavior as well as wheel activity of small laboratory animals during an experiment. Your individual system configuration can be found in the order documentation. - Page 12 The system devices can be operated in the given setup only. • If only individual components or parts of a system have been supplied by TSE Systems and the user makes up a complete system by using components from other manufacturers, then it is the user’s responsibility to ensure that the individual components are properly matched to...
- Page 13 During operating mode of High-Speed Sensor Unit, ensure that… o …its sensors are supplied with air from reference gas cylinder continuously. o …all other devices of the CaloSys module entered operating mode as well. o …PhenoMaster software is running. • Power OFF High-Speed Sensor Unit after use.
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Page 14: Fig. 3 Hardware Layout - Rod Nipple
PhenoMaster | Hardware Operating Instructions Drinking and Feeding measurements • The drinking and feeding sensors can be used with the dispensers supplied by TSE only - if others are used, measuring errors will occur. • (Re)assembly of rod drinking nipples... -
Page 15: Improper Use
Core Modules Activity measurements via infrared sensors (InfraMot) • Infrared sensors supplied by TSE should be used only. • There should be no external heat source in the measuring area of the sensor - and no persons should stand directly in front of the cage. -
Page 16: Ambient Conditions
PhenoMaster | Hardware Operating Instructions • Vacuum pumps (pull principle respirometry, underpressure principle) o Under no circumstances you should grease or oil the pump! o Choking the air flow by reducing the outlet or closing it leads to premature wear of the pump. -
Page 17: Loudness In Laboratory
Ensure that there is sufficient distance between the cages! Under no circumstances should occurrences in one cage interfere with the measurements made in neighbouring cages! 2.8.1. Space Requirements When setting up the system, ensure that... • …all the devices for controlling and operating the system are freely accessible. info@TSE-Systems.com www.TSE-Systems.com... -
Page 18: Transport In Laboratory
PhenoMaster | Hardware Operating Instructions • …the device ventilation slots are NOT blocked. • …information and safety warnings are NOT covered up. 2.9. Transport in Laboratory • Transport the system devices only when… o …they are powered OFF. o …the cables have been unplugged. -
Page 19: Operating Principle
By using a trial monitor, the amount removed during the trial can be followed; this makes it easier to recognize the necessity of refilling the dispenser. info@TSE-Systems.com www.TSE-Systems.com... -
Page 20: System Description
PhenoMaster | Hardware Operating Instructions For activity measurements via infrared sensors (InfraMot), passive infrared sensors are used. These sensors register the activity of one or more subjects by sensing the body heat image, i.e. infrared radiation and its spatial displacement over time. In this way, movement within the cage can be reliably determined. -
Page 21: Pc Requirements
Running of malware scanner software is permitted only when peripheral devices (e.g. USB memory stick, external hard disk drive) are connected to the system. • Malware scanner software updates are permitted immediately after the start of the PC only. info@TSE-Systems.com www.TSE-Systems.com... -
Page 22: Whitelist
PhenoMaster | Hardware Operating Instructions NOTICE - Data loss! Malware scans of system data can result in a data loss. Do NOT allow malware scanner software to scan settings files, results files or log files (see Section 4.1.1). 4.1.1. Whitelist The following directories and files should be excluded from virus scans. -
Page 23: Installation Drivers, Interface, Software
Without prior consulting Service, do NOT overwrite pre-installed software. Without prior consulting your system administrator AND TSE, do NOT alter BIOS settings of PC! 5.1. Interface Driver Drivers (PCIS-DASK) are designed for Windows7/Windows10. Supplied on DVD. - Page 24 PhenoMaster | Hardware Operating Instructions • Enter name and organization and press "Next". • Press "Next" to confirm the default destination directory. Without prior consulting Service, the default destination directory should not be altered. info@TSE-Systems.com www.TSE-Systems.com...
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Page 25: Interface Installation
Press "Yes" to reboot the PC. • Shut down Windows again and power OFF PC. Proceed to interface installation (see Section 5.6). 5.2. Interface Installation NOTICE - Instrument damage! Static electricity or touching the circuitry can damage the interface. info@TSE-Systems.com www.TSE-Systems.com... -
Page 26: System Software
5.3.1. Creating a Short-Cut It is also possible to create a short-cut after the installation of the program. • In data manager, change to the "PhenoMaster" directory. • With the right-hand mouse key, click "PhenoMaster.exe". • Drag the file onto the desktop with the right-hand mouse key. -
Page 27: Disabling Parameter "Automatically Adjust Clock For Daylight Saving Changes
With the right mouse-key, click on the time display on the Windows task bar. o In the context menu, select "Adjust date/time". o Select the "Date and Time" tab. Fig. 7 Date and Time tab (Windows7) o Press "Change time zone…" info@TSE-Systems.com www.TSE-Systems.com... -
Page 28: Fig. 8 Time Zone Settings (Windows7)
PhenoMaster | Hardware Operating Instructions Fig. 8 Time Zone Settings (Windows7) o Uncheck "Automatically adjust clock for Daylight Saving Time". o Press "OK". info@TSE-Systems.com www.TSE-Systems.com... -
Page 29: Connecting Devices - General
Place the animal cages on a stable support that ensures vibration-free operation, as otherwise the sensitive sensor measuring technique could be interfered with. Do not place the cages on the same support surface as the Control Units as these vibrate slightly. info@TSE-Systems.com www.TSE-Systems.com... -
Page 30: Cage Rack / Cage Lid Holder
PhenoMaster | Hardware Operating Instructions Cage Rack / Cage Lid Holder For a secure stand and simple operation, the system cages can be placed in a rack specially designed for them. A holder is provided for every calorimetry cage to take its lid when it is removed from the cage. -
Page 31: System Software
The system software is arranged modularly, i.e. depending on the system configuration the software functions that are necessary are enabled only. Functions that are disabled are either shown in gray or they are concealed. For further instructions, see Software Operating Instructions. info@TSE-Systems.com www.TSE-Systems.com... -
Page 32: Performing A Measurement
PhenoMaster | Hardware Operating Instructions Performing a Measurement It is assumed that… • …automatic switch OFF, screensaver etc. of PC have been deactivated. • …calibration for the sensors (drinking, feeding, body weight, calorimetry) has been carried out. • …>=2h prior to the test or a calibration of the sensors, all electronic calorimetry devices have been powered ON. - Page 33 During the measurement, check the procedure at reasonable intervals. • Remove condensate in the Air Drying Unit system as required. • After the measurement, remove the animals from the cages first and then only power OFF the air pump. info@TSE-Systems.com www.TSE-Systems.com...
- Page 34 PhenoMaster | Hardware Operating Instructions • We recommend that after an experiment has been stopped, the system is allowed to continue running for about 30min in order to replace the test air at the O2 and CO2 sensor by fresh air and to prevent contaminants from being deposited on the sensor.
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Page 35: Maintenance And Cleaning
Please contact Service. If you return contaminated system devices to TSE Systems, TSE Systems reserves the right to return any such device to your address immediately and will charge you for the dispatch costs. Should a contaminated device represent a health hazard, then we retain the right to take legal action. -
Page 36: Cage
Different material properties during heating may exclude such a device from sterilization, as otherwise fractures in the material could occur. Taking only individual material properties into consideration is NOT sufficient! TSE isn´t responsible for any device damages during sterilization due to different material properties! •... -
Page 37: Metallic Cage Lid
NOTICE - Instrument damage! If alkaline detergent residues or dried residues of softened water remain adhering to polycarbonate cages, material degradation could occur. • Thoroughly rinse the cages to remove any detergent residues. • Remove auxiliary detergents completely. info@TSE-Systems.com www.TSE-Systems.com... -
Page 38: Control Unit, Pc, Monitor, And Keyboard
PhenoMaster | Hardware Operating Instructions • When the cages are dry, no residues should be visible. • Carry out a visual check before sterilization. After cleaning and drying, the lower part of the cage can be autoclaved according to the cage material, see table below. -
Page 39: Cable
Racks should be wiped off, if required, with a moistened soft, lint-free cloth or tissue to remove any adhering dirt. A stainless steel cleaning agent can also be used to remove any stubborn dirt. Detergent residues should then be wiped off. After cleaning, the shelves can be decontaminated with H2O2 vapor. info@TSE-Systems.com www.TSE-Systems.com... -
Page 40: Appendix
PhenoMaster | Hardware Operating Instructions Appendix A. Example configurations Home cage configuration info@TSE-Systems.com www.TSE-Systems.com... - Page 41 Core Modules Calorimetry cage w/ 2x Access Control, 1x Drink, 1x Feed, 1x Body Weight Calorimetry cage w/ 1x Access Control, 1x Drink, 1x Feed, 1x Body Weight (w/o sensor) info@TSE-Systems.com www.TSE-Systems.com...
- Page 42 PhenoMaster | Hardware Operating Instructions Calorimetry cage w/ 1x Access Control, 1x Drink, 1x Feed, 1x Swivel mount Assembly group calorimetry cage lid for swivel Assembly group calorimetry cage lid* Assembly group swivel mount Assembly group Access Control dummy *...
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Page 43: Cage Body Specifications
Core Modules B. Cage body specifications Type II Floor area [cm Overall dimension (W x D x H) 391 x 199 x 160mm (15.39 x 7.83 x 6.3inch) Plastic Type H-Temp Polysulfone (PSU) info@TSE-Systems.com www.TSE-Systems.com... - Page 44 PhenoMaster | Hardware Operating Instructions North America Europe/Asia TSE Systems, Inc. TSE Systems GmbH 186 Chesterfield Industrial Blvd. Siemensstr. 21 Chesterfield, MO 63005 61352 Bad Homburg Germany Phone: 1-636-536-6502 Phone: +49-(0)6172-789-0 Fax: 1-636-536-0840 +49-(0)6172-789-500 Toll-free Phone: 1-866-466-8873 (USA/CDN) E-Mail Info@TSE-Systems.com...
- Page 45 Core Modules info@TSE-Systems.com www.TSE-Systems.com...
- Page 46 Sophisticated Life Science Research Instrumentation https://www.tse-systems.com/support/technical-support-form/ Specifications subject to change without notice Copyright © 2017 TSE Systems International Group - All rights reserved www.TSE-Systems.com info@TSE-Systems.com...
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