Contents Contents Introduction ............................7 Intended Use ........................7 Using the documentation....................7 Additional documents ......................8 Responsibilities........................8 Validity ..........................8 Safety ..............................9 Warning notices ........................9 Safety instructions for the planning stage................. 10 2.2.1 Magnetic fields........................10 2.2.1.1 Control area........................
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Contents 5.3.3 Mechanical interactions ....................28 5.3.3.1 Ground and building vibrations..................28 5.3.3.2 Impact noise ........................30 5.3.3.3 Acoustic ..........................30 Planning details ..........................31 Measurements and room dimensions ................31 6.1.1 Overview........................... 31 6.1.2 Operating area........................32 6.1.3 Magnet area ........................32 6.1.4 Technical area ........................
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Contents 6.13.1 Laboratory furniture ......................71 Delivery and transport........................73 Maximum transport time ....................74 Packaging......................... 74 Magnet transport ......................75 7.3.1 Transport method and limit value ..................75 Transporting electronic cabinets..................77 7.4.1 Transport method and limits ..................... 77 Moving into the building....................
If there is a delay of receipt on the part of the MR system owner after readiness for shipment has been sent to Bruker BioSpin MRI, the MRI system owner may be charged for the resulting additional costs. The regulations on a delay of receipt are established in the General Business Terms and the "Terms and Conditions"...
Warning due to magnetic fields The super-conducting magnet may only be set into operation or uninstalled by personnel au- thorized by Bruker BioSpin MRI. All the necessary safety precautions, emergency plans, and controlled access areas must exist and be activated before operation may begin.
Safety Safety instructions for the planning stage There may not be any risk to people, buildings, or equipment when operating the system. The following safety aspects must therefore be considered even when planning the laboratory infra- structure and installing the system. 2.2.1 Magnetic fields The super-conducting magnet of the MR system continually produces a very strong magnetic...
Safety 2.2.1.1 Control area The control area is the three-dimensional area in which the magnetic field strength is 0.5 mT and higher. It is defined by the 0.5 mT stray field line of the particular magnet types. The MR system owner must ensure that the area can only be accessed by authorized person- nel.
N2 or He. In order to establish a second safety level, and especially for magnets that involve liquid He and N2, Bruker BioSpin MRI strongly recommends the installation of an O2 supervision system in the magnet room and in storage locations of cryogen liquids.
In relation to the health and safety of employees and laboratory animals, we refer to compliance with national specifications and regulations. Repairs by Bruker BioSpin MRI can only be carried out after decontamination of equipment has been demonstrated in writing and any damage to the health of Bruker BioSpin MRI employees has been ruled out.
It is the responsibility of the system owner to decide on such networks and to establish suitable safety mechanisms in his laboratory infrastructure. Bruker BioSpin MRI is not responsible for the connection to any remote supervision system, nor for any possible damage caused by the lab- oratory alarm system.
Standards and certification Standards and certification Standards Recently delivered MR systems meet the standards listed below in relation to electrical safety and electromagnetic compatibility: Safety ▪ EN/IEC 61010-2-1:2001 ▪ EN/IEC 61010-2-82:2002 EMC: ▪ EN/IEC 61326:2004 Compliance with electromagnetic compatibility cannot be guaranteed in every case when ex- isting MR systems are upgraded while components of the old MR system are reused.
Standards and certification To achieve the functionality of the MR system, the specifications for the environmental condi- tions of the different room areas must be met. See Chapter Planning details [31]. National standards for operating MR systems Compliance with all national standards for operating MR systems is the responsibility of the MR system owner.
Installation schedule Installation schedule Installation planning overview Planning for a BioSpec® installation comprises the following subject areas: ▪ Characterization the planned installation site in terms of its suitability for MR ▪ Planning the laboratory structure and operational procedures ▪ Planning the structure of rooms and buildings ▪...
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Installation schedule Magnet front view fitted with the AutoPac™ positioning system Top left Rear view of the magnet with CCM and an installed MRI CryoProbe™ Top right Control electronics of an MR system with three cabinets (no cooling cabinet) Bottom left Bottom right Cooling unit, compressor and gas cylinder of the MRI CryoProbe™...
The deadline for transferring the magnet planned at the outset and agreed with Bruker Bio- Spin MRI must be confirmed as binding to Bruker BioSpin MRI 12 weeks at the latest prior to actual transfer. See chapter Giving notice of readiness for shipment [19]...
BioSpin MRI employee have access to the installation site. ▪ The Bruker BioSpin MRI employee needs to obtain a key allowing access the installation site. If necessary, he must be allowed access to adjacent rooms and/or buildings and circuit diagrams, as well as facilities and systems in the building.
▪ Data archiving on central servers ▪ Data exchange between the operator console and analysis consoles If it is possible to connect externally to the Internet, procedures between operator and Bruker BioSpin MRI Customer Support can then be made easier: ▪...
Laboratory infrastructure and interactions Interactions The MR system and its surroundings may affect each other based on the following interactions: ▪ magnetic interactions ▪ electromagnetic interactions ▪ building vibrations and impact noise ▪ room air and cooling systems A distinction must be made in these items between ▪...
In exceptional cases, installation can be carried out despite high ferromagnetic mass density. Discuss the situation and possible counter-measures with the planners from your local Bruker BioSpin MRI branch.
Laboratory infrastructure and interactions Limit values of magnetic disturbances Limit values of magnetic disturbances Minimum distance Reference stray field Mobile sources of magnetic dis- strength turbance [mT] ferromagnetic objects < 1 kg ferromagnetic objects < 25 kg ferromagnetic objects < 250 kg ferromagnetic objects <...
Laboratory infrastructure and interactions 5.3.2 Electromagnetic interactions In the event of faulty installation or incorrect operation of an MR system, electromagnetic inter- ference to other equipment in the vicinity of the MR system can occur. Electromagnetic disturbances to the MR system have a negative impact on the disturbance-free operation of an MR system.
If this cannot be avoided, countermeasures with in the building can also be taken, e.g. by using an active shield (MACS) in the HF shielding cabin or by shielding with soft-mag- netic iron. Contact the planning office of your local Bruker BioSpin MRI branch. 5.3.2.2...
Laboratory infrastructure and interactions Maximum disturbance level Maximum disturbance level 19F–1H X nuclei (15N-31P) 30 dBuV/m 30 dBuV/m Table 5.7: Maximum disturbance level If increased disturbance is observed in this area, the frequency range concerned must be ana- lyzed more precisely and one of the following counter-measures taken when planning installa- tion: Countermeasure The safest countermeasure is the installation of an MR system in an HF shield.
Laboratory infrastructure and interactions Installation with an AutoPac™ RF shield Figure 5.3: Installation with an AutoPac™ RF shield RF shielding at the user end of the magnet Acoustic isolation RF shielded magnet housing RF shielding at the service end of the magnet RF shielded electronics cabinets with external wiring The magnet itself is RF shielded.
If none of the alternatives mentioned can be realized, additional passive or active vibration de- coupling must be evaluated by the builder. Please contact an engineering firm specializing in building vibrations for this and contact your local Bruker BioSpin MRI branch. ID: 182463115...
Laboratory infrastructure and interactions 5.3.3.2 Impact noise No significant coupling of impact noise into the building is to be expected due to the installation of the MR magnets on passive absorbers. 5.3.3.3 Acoustic Increased sound levels occur in the following areas of an MR system: ▪...
Planning details Planning details Details of preparation of various parts of the installation are provided in the following chapters. Due to the fact that multiple specialists are involved in the planning, the contents are divided accordingly. Measurements and room dimensions 6.1.1 Overview The room dimensions and the distances between the different areas of an MR system are in...
Planning details 6.1.2 Operating area The minimum amount of space required in the operating area is indicated by the size of the lab- oratory furniture. This must allow installation of a PC control computer with monitor and periph- erals. Additional specifications for the space required may result from local guidelines for organizing the work place, from the number of MR datastations planned and from the operation- al procedures and routes planned.
Planning details HF shielded cabin (Faraday cage) Use of a Faraday cage increases the size of the building shell needed for the magnet area in each direction by at least 30-40 cm. The height of the ceiling may be increased depending on the design by up to 65 cm.
Planning details Minimum space required in front of the various units Minimum space required behind the various units Optional extensions to an MRI system Measurements of objects in the technical area Measurements of objects in the technical area Unit Number Size (width x length x height) electronic cabinets...
Planning details 6.2.1 Filter plates When planning the Faraday cage, the following openings should be provided for filter plates and shielded exhaust vents these openings depend on the system's configuration. Schematic overview of the positions of the filter plates of an Farady cage corresponding to the example of the room layout in Fig.
Probe™: Probe™ option ▪ supplied by Bruker in-vivo filter plate feed for lines for ani- ▪ optional order from Bruker mal monitoring cabin ventilation HF filters for ventila- ▪ contained in the HF cabin option tion and fresh air sup- ▪...
Planning details Care should be taken in both cases to ensure that the supporting and contact surfaces are ab- solutely plane. The contract surfaces must be sealed prior to assembly of the filter plate with HF sealing tape. Assembly of filter plates with an installation frame (right) and directly screwed to the cage (left) Figure 6.5: Assembly of filter plates with an installation frame (right) and directly screwed to the cage (left) sheet copper of the Faraday cage external insulation of the shielding box...
Planning details Dimension diagram of filter plates Figure 6.6: Dimension diagram of filter plates Height Width Diameter of the bores Horizontal distance to first hole Vertical distance to first hole Horizontal distance between holes Vertical distance between holes Horizontal distance from edge of filter plate to center of bore hole Vertical distance from edge of filter plate to center of bore hole Maximum frame width ID: 182463115...
Planning details If there are no detailed drawings for the filter plates described below, the measurements to be used are those found in the following table. Measurements of the individual filter plates Filter plate [mm] Electronics 1100 Magnet Anesthetic gas ex- 87,5 87,5 traction...
Planning details ▪ The anesthetic gas filter plate is assembled in an installation frame or directly screwed to the cage For further details, please see chapter Anesthetic gas extraction [65]. 6.2.1.4 Filter plate for magnet exhaust system Position, alignment, and assembly ▪...
Planning details ▪ Fresh and ventilation in the ceiling area, exhaust in the floor area ▪ The ideal position is determined by the position of the air conditioning system connections. Air ducts should not blow directly on to the magnet. ▪...
▪ Vent outlet design ▪ Electrical grounding ▪ Your local Bruker BioSpin MRI office will be happy to help you with planning the exhaust vent and is able to supply you on request with suitable quench pipe components. -- Example: -- Exhaust vent system Figure 6.8: Exhaust vent system...
Planning details 6.3.1 Design criteria of the exhaust system The exhaust system must be designed and calculated in such a way that: ▪ The connection of the exhaust vent is immediately above the magnet's outlet point ▪ The maximum pressure drop along the line does not exceed 400 mbar ▪...
Planning details Position of the exhaust vent for magnet 117/16 USR Distance from the center of the 39 cm magnet dewar Diameter at the connection point 19,88 cm Height 244 +/- 2 cm 6.3.2 Calculating the exhaust system The following aspects must be considered when calculating the exhaust system: ▪...
Planning details Section of the exhaust vent Portions of the exhaust gas line Portions of the exhaust gas line Figure 6.10: Section of the exhaust vent Calculation sections of the exhaust pipe Segment L [m] D [mm] Pos [m] DP [mbar] 0.5 x 1.4 = 0.7 90°...
Planning details 6.4.1 Surface loads and weights In order to guarantee the load-bearing strengths for the installation and operation of the instru- ment, the system owner must perform a professional calculation and verification of the autho- rized surface load at the installation site and all transport routes. This analysis can be performed on the basis of the sizes, transport and operation weights of the different components: Surface loads and weights...
Specific solutions are possible in special cases for achieving load distribution in existing build- ings. These solutions should be analyzed in relation to their vibration behavior. Discuss the sit- uation and possible counter-measures with the planners from your local Bruker BioSpin MRI office.
Planning details Position of the magnet on the foundation; Position of the vibration absorber (1) and of the connection point of the vertical exhaust vent (2). A-A refer to the center of the magnet dewar. Position des Magneten-ALLE Figure 6.12: Position of the magnet on the foundation; Position of the vibration absorber (1) and of the con- nection point of the vertical exhaust vent (2).
When installation is completed correctly, seismic safety is verified by statistical calculations in these cases up to the limit values listed below. Copies of the verified calculations can be requested from the local Bruker BioSpin MRI office. WARNING Warning of serious injury due to uncontrolled moving objects during an earth- quake.
Planning details Floor construction and anchorage for seismic safety Floor construction and anchorage for seismic safety Properties Specification Reinforced concrete state cracked concrete, normally reinforced Category of resistance to pressure for con- C 20/25 crete Minimum floor thickness 300 mm Maximum height of the floor construction 50 mm Floor anchor type...
Planning details Seismic protection system in an HF shielding box with "Faraday Cage Connection Kit Figure 6.13: Seismic protection system in an HF shielding box with "Faraday Cage Connection Kit ID: 182463115...
Planning details Seismic protection system on the magnet Figure 6.14: Seismic protection system on the magnet Electrical installations 6.5.1 Overview Electrical installation comprises the following planning and work package: ▪ Preparation of the electrical house connection ▪ Preparation of a local equipotential bonding in the technical area ▪...
Equipotential bonding: Earthing point on the building side, which is used solely for the MR system Equipotential bonding: Equipotential bonding bars in the technical room as a central neutral point of all MR system parts Central Bruker BioSpin MRI electrical distributor outgoing circuits to all MR system con- sumers Power connection 4, 5...
Equipotential bonding: Equipotential bonding bars in the technical room as a central neutral point of all MR system parts central Bruker BioSpin MRI electrical distributor outgoing circuits to all MR system con- sumers Generator or transformer on the building side for provided the mains voltage required...
Planning details Disposals electrical distribution Voltage/CEE form Fuse 400/230V 50/60 Hz 25 A (1F4) Gradient cabinet (Option: high power) 400/230V 50/60 Hz 25 A (2F4) Dual Loop Heat Exchanger for magnet and gradients, incl. magnet compressor 400/230V 50/60 Hz 16 A (3F4) Control electronics of the MRI system 400/230V 50/60 Hz 16 A (4F4)
Planning details 6.5.6 Connection and assembly of electrical distributor The assembly and the connection of the electrical power distributor to the main power supply is the MR system owner's task. In order to be able to finish the electrical installation before instal- lation of the MR system begins, the electrical power distributor can be delivered in advance.
Detailed planning of cable lengths and compliance to these plans during the final installation is a basic prerequisite for smooth installation of an MR system. The local project leader must immediately notify Bruker BioSpin MRI of any change to the cable lengths required during the planning stage. Changes to construction of the installation, which only become known during installation of the system, lead to enormous time delays.
Planning details Overview of the external line set Figure 6.18: Overview of the external line set 1 (*) Control cables to the operating room. Cables are routed through a cable duct (min 10 cm diameter) or on a small cable tray that the customer must provide. Scanner control line: Cable set in the shielded cabin.
Planning details The external cable set is run along the open cable trays assembled at ceiling height. The cus- tomer must have the cable trays installed and completely finished before installation of an MR system begins on site. Access for placing cables in the cable tray must be freely available during installation of an MR system.
Planning details 6.7.1 Line lengths for the MRI CryoProbe The following additional components must be considered when planning the cable routes when an MRI CryoProbe™ is planned to be used. See Table Measurements of the MRI Cryo- Probe™ units in the technical area [35] Power supply for CRP components Helium gas cylinder...
Planning details Lighting system The lighting facility is not an integral part of the supply and must be finished by the customer before installation begins. There are no system specific requirements for the operating and technical rooms. When select- ing the lighting facility in these areas, the country specific specifications and requirements for work place lighting must be met (occupational standards).
Planning details 6.9.2 Air conditioning systems It must be noted when planning the outlet openings of the space cooling that the air flow pro- duces indirect cooling. The cold air flow must not be directly aimed at parts of the MR system. All details listed reflect operation within the system's permitted limits.
Planning details The following additional cooling performances in the technical room must be taken into account when selecting options for a standard configuration. Further requirements for the space cooling in the technical room Further requirements for the air-conditioning system in the technical room Equipment options: Further requirements for the space Additional cooling perfor- cooling for the technical room...
90° bend with inner diameter of 110 x 54 mm. Set for anesthetic gas extraction system If the system is installed within an HF shielded room, suitable connecters, extensions and HF filtered feed through elements can be ordered under the Bruker part number T11976. 6.10 Cold water supply Part of the heat dissipated from the MR system is released via a heat exchanger to a cold water supply system.
Planning details Figure xy: (1) relation for the required input pressure difference (dP) and the corresponding pri- mary water temperature (T) for the total required cooling capacity of approx.11 kW. Other equipment options do not require any addition connections to the cold water system. Attention should be paid to ensure that the required values are checked before installation be- gins.
(inside or outdoors) can be included in the plans. These systems are planned, installed, and maintained by local refrigeration technology firms. Bruker BioSpin MRI can help with planning and supplying these systems if necessary, but not with installing and maintaining them.
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This can guarantee operation of the magnet over several days. For this reason, Bruker BioSpin MRI recommends installation of equivalent connection points for drinking water in the technical room in the event of an emergency.
NORMALBETRIEB__Füllmenge/Intervalle_USR-Magnete Normal operation: During normal operation of USR magnets, no cryogen liquids are required. For the maintenance of the cold head up to 500 l He can be refilled through the Bruker BioSpin MRI service. 6.12 Compressed air and gas supply No compressed air or gas supplies are required to operate the MR system without the MRI Cryo- Probe™.
Laboratory furnishings 6.13.1 Laboratory furniture The laboratory furniture is not supplied by Bruker BioSpin MRI At the time the MR system is set into operatioin, a minimum of a sufficiently large desk with office chair must be provided by the owner.
Magnet and electronics installation must always be planned and carried out in close cooperation with the local Bruker BioSPin MRI office. On the day the magnet is placed, a Bruker BioSpin MRI employee must be on site. Planning of delivery and transport must comprise the following items: ▪...
The magnet is transported and delivered cold. This therefore results in a maximum transport time of 10 days between the time that the magnet is picked up at Bruker and installation at the customer's. If it can be predicted at the planning stage that this maximum time span cannot be adhered to, appropriate intermediate storage must be planned which includes liquid helium fill- ing of the magnet.
Delivery and transport Transport pallets for air freight Figure 7.2: Transport pallets for air freight Magnet transport Magnets are highly sensitive and in some instances very heavy structures filled with cryogenic liquids and gases. They may only be transported when they are not on field and with special transport devices and in no case may they be subject to high acceleration or jolts.
Delivery and transport ▪ The magnet may only be lifted with hangers for heavy loads that are long enough for strong sideways forces not to have any impact on the crane hooks. Alternatively, a special heavy load frame can be used to lift the magnet. ▪...
Delivery and transport Transporting electronic cabinets The electronics cabinets contain sensitive and sometimes very heavy assemblies. Sometimes the cabinets have a high center of gravity and are therefore in danger of tipping. The cabinets may not be tipped during transportation, they may not get wet and they may not be subject to high acceleration and jolting.
Delivery and transport Transport limitations Transport limitations [schreibgeschützt] transport restrictions 117/16 USR Limit value Maximum horizontal acceleration 2.0 g Maximum vertical acceleration 3.0 g Maximum duration during maximum acceleration 20 ms Maximum tilt angle 10° No sliding on loading surfaces. No contact with other transport goods Only gentile placement No tilting by more than 10°...
Delivery and transport Transport dimension of the magnet. (1) in the standard transport situation and (2) for the case, when the U-rails are removed. Figure 7.4: Transport dimension of the magnet. (1) in the standard transport situation and (2) for the case, when the U-rails are removed.
Delivery and transport Unloading situation of transport by lorry Figure 7.5: Unloading situation of transport by lorry The magnet and electronics must be unloaded from the particular means of transport at the in- stallation site with a crane and this requires adequate free surfaces in the entrance area. The transport route must have the following features along its entire stretch: ▪...
If there are no suitable transport routes within the building to the magnet's installation site, spe- cial procedures for moving it may be used. In these instances, please contact the local Bruker BioSpin MRI office to plan the best solution together with them.
- Suitable pressure valves must always be used for transportation. Disposal of an MR system must be take place according to local regulations. Contact the planning office of your local Bruker BioSpin MRI branch. Residual magnetization in the building Increased residual magnetization in the building's ferromagnetic materials can remain after an MR system has been dismantled.
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Moving or dismantling the MR system ID: 182463115...
6 weeks at the latest prior to the scheduled installation date and sent, signed, to your Bruker BioSpin MRI branch. If the completed check list does not reach the local Bruker BioSpin MRI branch in time, instal- lation by Bruker BioSpin on the scheduled date may be canceled and postponed.
Is the transportation company adequately insured against trans- port damage so that the value of the MR system is covered? (Transport from the loading ramp at Bruker BioSpin MRI to the installation site.) Did the transport company visit the installation site and did they...
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Is a separate and lockable room close to the MR system avail- able that can be used solely by Bruker BioSpin MRI during the installation? Are the installation rooms (MR area) lockable and the key force,...
Checklist for preparing to install the system Laboratory rooms features Magnet room, area where the magnet is located: Will the magnet room be finished on time? Will the floor be finished on time? Will the ceiling be finished on time? Will the electrical installations be finished on time? Are the cable trays installed? Will the air conditioning or ventilation be ready for operation at...
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Checklist for preparing to install the system Operating area, area of the MR operating workstation: Will the operating area be finished on time? Will the ceiling be finished on time? Will the floor be finished on time? Will the electrical installations be finished on time? Do both electrical 230V/10A sockets exist? Is the distance that the system cables must span to the electron- ic cabinets less than 25 meters?
Checklist for preparing to install the system Declaration As the person named responsible for the MRI system by the customer, I hereby confirm the details given beforehand: Place, date: _____________________________________________________ Name: __________________________________________________________ (in block letters) Signature: ____________________________________________________ ID: 182463115...
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Figures Figures Figure 2.1: Fig. 2.1: Hazardous zones ..................... 10 Figure 4.1: Fig. 4.1: Installation planning overview................17 Figure 5.1: Mobile sources of magnetic interference................ 23 Figure 5.2: Installation in an RF shielded cabin (Faraday cage) ............27 Figure 5.3: Installation with an AutoPac™...
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Tables Tables Table 5.1: Limit values of magnetic disturbances................24 Table 5.2: Interference fields of equipment ..................24 Table 5.3: Disturbance in the magnet room ..................25 Table 5.4: Disturbance in the technical room ..................25 Table 5.5: Disturbance in the vicinity....................26 Table 5.6: Frequency ranges for commonly used NMR nuclei............
Index Index potential compensation wall rail..... 56 Checklist ............. 85 Acoustic .............. 30 Compressed air ..........70 sound level............. 30 Connection cable for electrical......62 acoustic absorption ..........30 Connection values in the technical room technical Air conditioning systems ........64 room outlet openings ..........
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Index delay in acceptance ..........20 Building administrators ........12 delivery..............19 Building security ..........12 transport route..........80 defribillators ........... 12 Delivery ............73, 73 emergency lighting ........12 Planning of delivery........73 Emergency paramedics ......... 12 detectors ............. 13 Fire department ..........
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Index assembly............41 gas extraction system for cryogenic gases..42 filter plates gas supply............70 anesthetic gas filter plate ....... 37 Ground and building vibrations ......28 Assembly of filter plates ......... 38 Ground vibrations cabin ventilation ..........37 Countermeasure ..........29 Dimension diagram of filter plates....
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Index ground loops ..........35 Low frequency interference ........ 25 HF-interference ........... 27 High frequency interference ........ 25 magnet area............30 Humidity ............64, 64 Magnet filter plate ..........40 assembly ............40 Impact noise............30 Magnet foundation ..........48 In the case of a quench........
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Index medical implants ..........11 Minimum space required for magnets....32 railway lines ............25 Mobile sources of magnetic disturbance..... 23 Readiness for shipment ........19 Moving into the building ........78 readiness for shipment ......... 8 Moving the MR system ........83 relieve strain ............
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Index Electronic cabinets......... 34 Maximum vertical acceleration ....76, 78 Measurements of objects in the technical area... Transport method and limit value air pads ............76 Measurements of the MRI CryoProbe™..35 crane.............. 75 Measurements of the MRI Parallel Transmit™ ... rail ..............
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