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Summary of Contents for Quattroflow QF1200
- Page 1 Quattroflow Installation, Operation & Troubleshooting Guide Version: Rev. 0 (July 2017)
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Page 2: Table Of Contents
Quattroflow Installation, Operation & Troubleshooting Guide Rev. 0 INDEX Introduction ..............................4 Basics ................................5 General description of Quattroflow Pumps & Functioning ..............5 Volume flow and pressure ........................6 Medium ................................. 7 Chemical resistance ..........................7 Solids and suspensions .......................... 8 Sticky Mediums ............................. - Page 3 Quattroflow Installation, Operation & Troubleshooting Guide Rev. 0 Revision Date Changes/ Comment Issued by July 2017 First Release Tim Dudda Page 3 of 25 www.quattroflow.com...
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Page 4: Introduction
Quattroflow Diaphragm Pumps. This document contains basic knowledge how Quattroflow Pumps work and explanations regarding the technical and physical principals. It should help to project the right Quattroflow Pump for each application and it gives important points for consideration for planned systems. -
Page 5: Basics
Quattroflow pumps can be found in all areas of biologic manufacturing such as cross-flow filtration systems, chromatography, and centrifuges. Quattroflow ensures safety, efficiency and reliability for handling biologics such as plasma products, therapeutic proteins, monoclonal antibodies, vaccines, and other high value products. -
Page 6: Volume Flow And Pressure
The higher the back pressure in your system the lower is the max. flow rate at same pump speed (see Figure Medium (density and viscosity): All shown Quattroflow pump curves are valid for water at room temperature that means a density of approx. 1000 kg/m³ and a dynamic viscosity of approx. 1 mPa*s (= 1 cP). -
Page 7: Medium
3 MEDIUM Chemical resistance The table below shows the standard product wetted materials for multiple-use and single-use Quattroflow pump chambers. The second table shows an overview of the chemical resistance against some mediums which are often used with Quattroflow Pumps. -
Page 8: Solids And Suspensions
Quattroflow Installation, Operation & Troubleshooting Guide Rev. 0 Substance Santoprene EPDM 1.4435 Isopropanol, Good Good Good Good Ethanol NaOH Good Good Good Good Good Mineral Oil Good recommended recommended (room temperature) NaCl Good Good Good recommended Acetic Acid Good Good... -
Page 9: Medium With High Viscosity
Rev. 0 Medium with high viscosity Generally Quattroflow pumps can handle medium viscosities up to 1000 mPa*s (cP). The higher the viscosity of the medium the lower is the maximum reachable flow rate of the pump (see Table 3 below). -
Page 10: Installation
High pressure 3.: Outlet line 4.: Flow direction Figure 5 Exemplary set up for a Quattroflow pump. Suction line Make sure that the internal diameter from the suction line is large enough (typically equivalent with the internal diameter form the pump connector). Flow velocities should typically be below 2 m/s. Consider larger diameters for fluids with higher viscosities. -
Page 11: Flow Directions
"IN" (inlet) and "OUT" (outlet). Please see the drawings below for Quattroflow pump chamber orientation which are supplied as standard ex works. All QF pump chambers can be rotated in 90° steps to adapt the pump to your process and application. -
Page 12: Start-Up Operations
If you have ordered a complete QF pump the stainless steel pump chamber is built-on ex works. If you have ordered a Quattroflow Single-Use Pump or just a Single-Use pump chamber, the chamber will be supplied separately. The front crews and the clamping ring screw have to be tightened with the defined torque which is given in the user manual. -
Page 13: Priming
Rev. 0 Priming Quattroflow pumps are self-priming and can run dry (no use of mechanical seals). Please note that the pump needs to be properly primed in order to achieve a stable flow and low pulsation. A minimum flow rate is required for the priming (complete removal from air inside the pump chamber). The following table indicates the minimum required pump speed for water with <0.5 bar discharge pressure. -
Page 14: Cleaning
(only for QF1200SU) CIP – Cleaning in place The Quattroflow pump (multiple use) can be used as active CIP-pump to pump the CIP medium through the complete skid. Also it is possible that another external pump is used as CIP-pump. Please find some further information for both operating modes below. - Page 15 Quattroflow Installation, Operation & Troubleshooting Guide Rev. 0 CIP with external pump: If you use another external pump for you CIP-process, the passive Quattroflow Pumps will be rinsed freely. Please note the given important information below. Temperature for CIP-medium: max. 90 °C (194 °F) Pressure: max.
- Page 16 Pressure sensor: 3/4“ Flow rate [l/h] Differential pressure [barg] < 0,1 < 0,1 Table 8 Pressure drop of QF1200 pump chamber at different flow rates. Water @ RT Pump size: QF4400 / QF5050 Pressure sensor: 2“ Flow rate [l/h] Differential pressure [barg]...
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Page 17: Sip - Steaming In Place
Blow down after SIP process Quattroflow MU Pumps can handle a so called blow down process that is often executed after the SIP cycle. Blow down is used cooling down the system and removing the residual condensate out of the system over steam traps. -
Page 18: Autoclave
Quattroflow Installation, Operation & Troubleshooting Guide Rev. 0 Autoclave For autoclaving of the pump chamber we recommend the following steps. 1. CIP of the pump chamber with any suitable process 2. Empty the pump 3. Remove the pump chamber from the pump drive 4. -
Page 19: Drainability Of Quattroflow Pumps
Optimized drainability: orientation of the pump chamber There is the possibility to rotate the pump chamber in 90° steps for all Quattroflow pump sizes. This rotation is independent of the orientation of the pump drive which stands standardly horizontally on the ground. - Page 20 Quattroflow Installation, Operation & Troubleshooting Guide Rev. 0 QF4400 QF5050 QF20K Standard orientation Optimized drainability Pump drive horizontally (standard) inlet up, outlet down (standard) Table 11 Standard and optimized orientation of QF pump chambers (QF4400, QF5050, QF20K). Page 20 of 25...
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Page 21: Full Drainability: Vertical Position Of The Pump (Pump Chamber Downwards)
Full drainability: Vertical position of the pump (pump chamber downwards) To reach a full drainability of Quattroflow Pump chambers there is the possibly to mount the complete pump drive and pump head in vertically position. There are some figures below which show this orientation exemplary. - Page 22 Quattroflow Installation, Operation & Troubleshooting Guide Rev. 0 QF4400 QF20K Full drainability Pump drive Vertically, Pump chamber downwards Figure 9 QF4400 and QF20K orientation for full drainability. Please contact the support team to get more information on vertical installation of QF4400 and QF20K pumps.
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Page 23: Troubleshooting
Rev. 0 8 TROUBLESHOOTING Quattroflow pumps operate very reliable and error-free, if they will be operated and serviced in accordance with the instruction manual. If there is still a problem the following table should help detecting and fixing the cause by yourself. - Page 24 Quattroflow Installation, Operation & Troubleshooting Guide Rev. 0 Continuation of Troubleshooting Table 1: Operating troubles Cause / remedial action Bearings are worn or defective and must be replaced. The valves are dry (e.g. not in use for a long time), deformed or worn.
- Page 25 Quattroflow Installation, Operation & Troubleshooting Guide Rev. 0 Subject to change without notice. ALMATEC Maschinenbau GmbH Carl-Friedrich-Gauss-Str. 5 · 47475 Kamp-Lintfort · Germany Telephone +49.2842.9610 · Telefax ++49.2842.96140 http://www.almatec.de · e-mail: info@almatec.de Page 25 of 25 www.quattroflow.com...
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