Contents Regulatory Notices ....................... 4 Safety Information ......................6 Specifications ........................ 7 Overview of Components ..................... 9 Rear I/O Panel ......................10 UID LED Button ..................... 10 COM Port ....................... 10 VGA Port ........................ 10 Connector ..................10 USB 3.2 Gen 1 Port (USB 3.2 Gen 1/ USB 2.0) ............10 GbE RJ45 Port (for mgmt.) ...................
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Connectors ........................20 Power Connectors ....................20 JATX12V1: 12PIN ATX Power Connector ............20 ATX4PIN1: 4PIN ATX Power Connector ............20 SATAPWR1: SATA Power Connector ............21 JSDOMPWR1: SATA DOM Power Connector ..........21 Cooling Connectors ....................22 FAN1~8, PUMP1: Fan Power Connectors ............. 22 Other Connectors ....................
Chemical Substances Information In compliance with chemical substances regulations, such as the EU REACH Regulation (Regulation EC No. 1907/2006 of the European Parliament and the Council), MSI provides the information of chemical substances in products at: https://csr.msi.com/global/index CE Conformity Hereby, Micro-Star International CO., LTD declares that this device is in compliance with the essential safety requirements and other relevant provisions set out in the European Directive.
Safety Information ∙ Always read the safety instructions carefully. ∙ Keep this User’s Manual for future reference. ∙ Keep this equipment away from humidity. ∙ Lay this equipment on a reliable flat surface before setting it up. ∙ The openings on the enclosure are for air convection hence protects the equipment from overheating.
Specifications Model MS-S3261 Form factor Micro-ATX Dimensions 243.84mm (9.6”) x 243.84mm (9.6”) Processor ∙ 1 x AMD® Ryzen™ 7000 Series Processor, TDP up to 170W - Processor socket AM5 Chipset AMD B-Class Chipset Memory ∙ 4 x DDR5 memory slots, supporting up to 128GB - Supports UDIMM 5200MT/s (2DPC), ECC/ non-ECC Networking ∙...
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Model MS-S3261 Rear I/O ∙ 4 x USB 3.2 Gen 1 Type-A ports (USB 3.2 Gen 1/ USB 2.0) ∙ 4 x 1GbE RJ45 ports ∙ 1 x GbE RJ45 ports (Mgmt.) ∙ 1 x COM port ∙ 1 x HDMI™ Connector ∙...
Rear I/O Panel GbE RJ45 Port (for mgmt.) COM Port VGA Port UID LED Button GbE RJ45 Port USB 3.2 Gen 1 Port (USB 3.2 Gen 1/ 2.0) UID LED Button The UID (Unit Identification) button help users identify and locate a system, especially in high-density rack environments.
GbE RJ45 Port (for mgmt.) Connect a specially configured RJ45 console cable to this jack for network routers/ switches to communicate with the system through a serial connection. Link/ Activity LED Speed LED Status Description Status Description No link Linked Orange 100M Green Data activity...
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Component Contents Component Page CPU Socket Memory DIMMA1~2, DIMMB1~2: DDR5 DIMM Slots Storage SATA5_6, SATA1~4: SATA 3.0 6Gb/s Ports M2_1~2: M.2 Slots (M Key, PCIe 4.0, 22110/ 2280) Expansion Slots PCIE_1~2: PCIe Expansion Slots Connectors Power Connectors JATX12V1: 12PIN ATX Power Connector ATX4PIN1: 4PIN ATX Power Connector SATAPWR1: SATA Power Connector JSDOMPWR1: SATA DOM Power Connector...
CPU Socket Introduction to the AM5 CPU The surface of the AM5 CPU has two notches and a golden triangle to assist in correctly lining up the CPU for motherboard placement. The golden triangle is the Pin 1 indicator. ⚠ Important Overheating will seriously damage the CPU and system.
CPU & Heatsink Installation Use appropriate ground straps, gloves and ESD mats to protect yourself from electrostatic discharge (ESD) while installing the processor. ⚠ Important Images are for illustration purposes only; actual parts may vary. CPU Socket...
Memory DIMMA1~2, DIMMB1~2: DDR5 DIMM Slots DIMMA1 DIMMB1 Channel A Channel B DIMMA2 DIMMB2 Recommended Memory Population Quantity of DIMMs DIMMA1 Channel A DIMMA2 DIMMB1 Channel B DIMMB2 **“V” indicates a populated DIMM slot. ** ⚠ Important Only support UDIMM. ∙...
Installing Memory Modules 1. Open the side clips to unlock the DIMM slot. 2. Insert the DIMM vertically into the slot, ensuring that the off-center notch at the bottom aligns with the slot. 3. Push the DIMM firmly into the slot until it clicks and the side clips automatically close.
Storage SATA5_6, SATA1~4: SATA 3.0 6Gb/s Ports These connectors are SATA 6Gb/s interface ports, it can connect to SATA devices. SATA4 SATA3 SATA2 SATA1 SATA5_6 ⚠ Important ∙ Please do not fold the SATA cable at a 90-degree angle. Data loss may result during transmission otherwise.
M2_1~2: M.2 Slots (M Key, PCIe 4.0, 22110/ 2280) Please install the M.2 solid-state drive (SSD) into the M.2 slot as shown below. ⚽ Video Demonstration Watch the video to learn how to Install M.2 SSD. M2_1 M2_2 Installing M.2 SSD 1.
Expansion Slots PCIE_2: PCIe 4.0 x 8 slot (Gen 4 x 4 signal from CPU) PCIE_1: PCIe 5.0 x 16 slot (Gen 5 x 16 signal from CPU) PCIE_1~2: PCIe Expansion Slots The PCI Express(Peripheral Component Interconnect Express) slots support PCIe interface expansion cards.
Connectors Power Connectors JATX12V1 SATAPWR1 JSDOMPWR1 ATX4PIN1 JATX12V1: 12PIN ATX Power Connector This connector allows you to connect an ATX power supply. +12V_bp-1 GND-1 +12V_bp-2 GND-2 +12V_bp-3 GND-3 JATX12V1 +12V_bp-4 GND-4 +12V_bp-4 GND-5 +12v_bp-6 GND-6 ATX4PIN1: 4PIN ATX Power Connector This connector is used to provide power to ATX power supply.
SATAPWR1: SATA Power Connector This connector is used to provide power to SATA devices. SATAPWR1 P12V JSDOMPWR1: SATA DOM Power Connector This connector is used to provide power to SATA DOM devices. JSDOMPWR1 ⚠ Important Make sure that all power connectors are securely connected to the power supply to ensure stable operation of the motherboard.
Cooling Connectors FAN1~8, PUMP1: Fan Power Connectors The fan power connector supports system cooling fans with +12V. When connecting the wire to the connectors, always note that the red wire is the positive and should be connected to the +12V; the black wire is Ground and should be connected to GND. FAN_TACH FAN1~8 P12V...
Other Connectors JFP1: Front Panel Connector The front panel connector is provided for electrical connection to the front panel switches and LEDs. PWR_LED+ FP_PWR No pin SYS_ID_LED+ PWR_LED- SYS_ID_LED- HDD_ACT_LED+ SYS_FAULT_LED1- HDD_ACT_LED- SYS_FAULT_LED2- PWR_BTN NIC#1_ACT_LED+ JFP1 PWR_BTN_GND NIC#1_ACT_LED- RST_BTN SMB_SDA RST_BTN_GND SMB_SCL SYS_ID_BTN...
JGPIO1: GPIO Header This connector is provided for the General-Purpose Input/Output (GPIO) peripheral module. USER_GPIO0 USER_GPIO1 USER_GPIO2 USER_GPIO3 JGPIO1 USER_GPIO4 USER_GPIO5 USER_GPIO6 USER_GPIO7 No pin JPMBUS1: PMBUS Box Header Power Management Bus (PMBus) is a variant of the System Management Bus (SMBus) which is targeted at digital management of power supplies.
JCHASSIS: Chassis Intrusion Header This connector connects to the chassis intrusion switch cable. If the chassis is opened, the chassis intrusion mechanism will be activated. The system will record this status and show a warning message on the screen. To clear the warning, you must enter the BIOS utility and clear the record.
JUSB1: USB 3.2 Port Box Header This port is backward-compatible with USB 2.0 devices and supports data transfer rate up to 5 Gbit/s (SuperSpeed). USB_VCC1 USB3_ESD_RX4N USB3_ESD_RX4P USB3_ESD_TX4N USB3_ESD_RX4P USB3_ESD_DN8 USB3_ESD_DP8 JUSB1 USB2_ESD_DP9 USB2_ESD_DN9 USB3_ESD_TX5P USB3_ESD_TX5N USB3_ESD_RX5P USB3_ESD_RX5N USB_VCC2 No Pin JUSB2: USB 3.2 Gen 1 Type-A Connector (USB 3.2 Gen 1/ USB 2.0) The USB (Universal Serial Bus) port is for attaching USB devices such JUSB2...
FP_I2C_1, RBP_I2C_1~2: I2C Box Headers I2C connectors are used to connect to the System Management Bus (SMBus). FBP_ I2C_1 is for front HDD backplane, and RBP_I2C_1~2 are for rear HDD backplanes. I2C_CLK FP_I2C_1 RBP_I2C_1 RBP_I2C_2 I2C_DAT JCOM1: COM Port Box Header This connector is a 16550A high speed communications port that sends/receives 16 bytes FIFOs.
Jumpers ⚠ Important Avoid adjusting jumpers when the system is on; it will damage the motherboard. JRTC_CLR1 JSEL_M2 JSEL_BMC1 Jumper Name Default Setting Description 1-2: Normal (Default) JRTC_CLR1 2-3: CMOS Clear 1-2: M.2_2 enabled, PCIE_2 disabled (Default) JSEL_M2 2-3: PCIE_2 enabled, M.2_2 disabled 1-2: Using CPU (Default) JSEL_BMC1 2-3: Using BMC...
Onboard LEDs BMC_LED1: BMC Heartbeat LED This LED indicates the BMC (Baseboard Management Controller) status. Status Description BMC is not activated BMC is functioning normally Blinking LED_H1, LED_L1: Port 80 Debug LEDs The Port 80 Debug LEDs display progress and error codes during and after POST (Power-On Self Test).