Sartorius Stedim Biotech BIOSTAT B-DCU Manuals

Manuals and User Guides for Sartorius Stedim Biotech BIOSTAT B-DCU. We have 1 Sartorius Stedim Biotech BIOSTAT B-DCU manual available for free PDF download: Operating Instructions Manual

Sartorius Stedim Biotech BIOSTAT B-DCU Operating Instructions Manual (186 pages)

Bioreactor/Fermenter

Brand: Sartorius Stedim Biotech | Category: Laboratory Equipment | Size: 14 MB

Table of Contents
3
About These Instructions
8
Validity
8
Accompanying Documents
8
Target Groups
9
Symbols Used
10
Warnings
10
Other Symbols Used
10
Safety Information
11
Intended Use
11
Qualification of Personnel
11
Significance of These Instructions
11
Proper Working Order of the Device
11
Safety Devices
12
Electrical Power
12
Energy Release
12
Gases
12
Accessories, Consumables, and Spare Parts
13
What to Do in the Event of an Emergency
13
Personal Protective Equipment
14
Components under Pressure
14
Escaping Substances
15
Hot Surfaces
15
Unintended or Unexpected Startup of the Device
15
Rotating or Moving Parts
15
Danger of Tripping or Slipping
16
Device Description
17
Device Overview
17
Control Unit
18
Supply Unit
20
Front View (With/Without Variable Area Flow Meter)
20
Front View of Connection Panel
21
Rear View of Connection Panel
22
Rear View
23
Aeration
23
Variable Area Flow Meter
24
Enrichment" and "Gasflow Ratio" Aeration Modules
25
Advanced Additive Flow" Aeration
26
Peristaltic Pumps
27
Integrated Peristaltic Pumps
28
External Pumps
29
Temperature Control Modules
29
Temperature Control Module for Double-Walled
29
Culture Vessels
29
Temperature Control Modules for Single-Walled
30
Culture Vessels
30
Stirrer Drive
31
Safety Devices and Protective Systems
32
Mains Disconnector
32
Overpressure Valves and Pressure Reducers
32
Aeration Segment Overpressure Valves
32
Overheating Protection
33
Symbols on the Device
33
Manufacturer's ID Labels
34
Software
35
User Information
35
System Start
35
Principles of Operation
36
User Interface
36
Header
37
Work Area
37
Footer
38
Display of Function Elements
40
Overview of the Main Function Keys
41
Overview of Selection Keys
42
Direct Function Keys for Selection of Submenus
42
Selection Lists and Tables
45
Password Protection of Individual Functions
45
User Management
46
Bug Handling and Troubleshooting
46
Locking Functions
46
Transport
47
Inspection Upon Acceptance by the Recipient
47
Reporting and Documenting Transport Damage
47
Checking Completeness of the Delivery
47
Packaging
47
Shipping Instructions
47
Installation
49
Ambient Conditions
49
Work Surfaces and Loads
49
Laboratory Energy Sources
50
Electricity
50
Temperature Control Medium
51
Gas Supply
52
Getting Started
53
Installation Materials
53
Connecting the Control Unit
53
Connecting the Control Unit to an External Host System
53
Connecting Network-Compatible Components to the Control Unit
54
Connecting the Supply Unit
54
Connecting the Supply Unit to the Control Unit
54
Supply Unit
54
Connecting Additional Components/Sensors to the Supply Unit
54
Connecting the Laboratory's Water Supply to the Supply Unit
55
Connecting the Laboratory's Gas Supply to the Supply Unit
55
Connecting Stirrer Drive
56
Connecting the Hoses for Aeration
57
Connecting the Univessel
57
SU Holder
57
Connecting the Barcode Scanner
58
Connecting the Temperature Control System
58
Double-Walled Culture Vessels/Single-Walled Culture Vessels
58
With Heating/Cooling Jacket
58
Heating Jacket
60
Connecting the Exhaust Cooling Hoses
62
Connecting External Pumps
62
Connecting the Balance
63
Switching the Control Unit and Supply Unit(S) On/Off
64
Preparing and Running the Process
65
Overview
65
Preparing the Glass Culture Vessels
65
Connecting Transfer Lines
66
Preparing the Cultivation Process
67
Mounting the Stirrer Drive
68
Installing the Heating/Cooling Jacket
70
Connecting the Aeration Modules
71
Conducting Preliminary Steps
71
Univessel ® SU Safety Valve Station
71
Connecting the "O
72
Aeration Modules
72
Aeration System
72
Preparing the Corrective Medium Supply
73
Performing a Process
76
Setting up the Measurement and Control System
76
Guarantee Sterility
76
Alternating Operation between Glass Culture Vessel and Univessel SU
77
Carrying out the Cultivation Process
77
Main" Menu
78
General Information
78
Process Displays in the "Main" Menu
79
Direct Access to Submenus
79
Trend" Menu
81
Trend Display
81
Changing the Settings for a Channel
82
Assigning a Process Value to a Channel
83
Calibration" Menu
84
General Information
84
Group or Single Calibration
85
Ph Calibration (Conventional Sensor)
86
General Information on Ph Sensors
86
Calibration Ph-#" Submenu
87
Performing Calibration
88
Direct Input of the Zero Offset and Slope
89
Perform Recalibration
89
Ph Calibration (Digital Sensor)
89
General Information on Ph Sensors
89
Calibration Ph-B#" Submenu
90
Performing Calibration
91
Direct Input of the Slope
92
Perform Recalibration
92
DO (Po ) Calibration (Conventional Sensor)
94
General Information on the DO
94
Sensors
94
Submenu
94
Performing Calibration
95
Direct Input of the Zero Offset and Slope
96
DO (Po ) Calibration (Digital Sensor)
96
General Information on the Digital DO (Po 2 ) Sensors
96
Calibration Po
97
B#" Submenu
97
Performing Calibration
98
Optical Ph and DO
100
Sensors
100
Signal Quality of the Optical Probes
100
Notes on Calibration
101
Ph Calibration (Optical Sensor)
101
Calibration Ph-#" Submenu
102
Entering Initial Calibration Data
103
Performing Recalibration
104
Configuring the Measurement Cycle for Ph Measurement
105
DO (Po ) Calibration (Optical Sensor)
106
Calibration Po2-#" Submenu
106
Performing Initial Calibration
107
Performing Recalibration
108
Configuring Measurement Cycles for DO
108
Measurement
108
Totalizer for Pumps and Valves
109
Balance Taring
111
Redox Calibration
112
Turbidity Calibration
113
Setting the Speed of the Internal Analog Pumps
114
Controller" Menu
115
Functional Principle and Equipment
115
Controller Selection
116
General Controller Operation
116
Setpoint Profiles
117
General Controller Parameterization
119
Output Limits
119
Dead Zone
119
Controller Parameterization Menu Screen
120
PID Parameters
120
PID Controller Optimization
120
Guide and Slave Controller (TEMP, JTEMP) Temperature
121
Measurement
121
Speed Regulation (STIRR)
122
Anti-Foam Controller (FOAM)
124
Level Control with Level Sensor (LEVEL)
125
Adjusting the "VWEIGHT" Gravimetric Level Controller
126
Adjusting the "FLOW" Gravimetric Filling Pump Controller
127
Filling Pump Controller (SUBS)
128
Adjusting Gas Controllers
128
Adjusting the Ph Controller
129
Regulation Methods
132
Adjusting the DO (Po ) Sensor Process Value Source
133
DO (Po ) Controller CASCADE (Cascade Controller)
134
DO (Po ) Controller ADVANCED (Polygon Controller)
136
Using Pumps from Ph, Foam, and Level Control for
143
Substrate Addition
143
Glucose Controller (GLUCO)
145
Customer-Specific Changes to Controllers
145
Settings" Menu
146
General Information
146
Changing System Settings
147
Measuring Range Settings
148
Manual Operation
149
Manual Operation for Digital Inputs
149
Manual Operation for Digital Outputs
151
Manual Operation for Analog Inputs
152
Manual Operation of Analog Outputs
153
Manual Operation for Controllers ("Control Loops")
154
Manual Operation of Sequence Control ("Phases")
155
Externally Connected Devices
156
Cleaning and Maintenance
157
Cleaning
157
Cleaning the Device
158
Cleaning the Culture Vessels
158
Maintenance
158
Maintenance Info
158
Maintenance Schedule
159
Carrying out Maintenance Work on Safety Components
160
Faults
161
Procedure
161
Hardware-Related Faults
161
Contamination" Troubleshooting Table
161
Counter Cooling System" Troubleshooting Table
162
Aeration and Ventilation" Troubleshooting Table
162
Process-Related Faults/Alarms
163
Alarm Triggering
163
Alarm Overview" Menu
164
Process Value Alarms
164
Alarms for Digital Inputs
166
Alarms, Meaning, and Corrective Measures
168
Process Alarms
168
Process Messages
168
System Alarms
168
Disposal
169
General Information
169
Information on Decontamination
169
Decommissioning the Device
170
Dismantling the Device
171
Disposal
171
Storage and Shipping
172
Storage
172
Storage Conditions
172
Packing/Return
172
General Information
172
Returning the Device
172
Technical Specifications
173
Control Unit
173
Dimensions
173
Mains Connection
173
Supply Unit
173
Mains Connection (120 V Version)
173
Mains Connection (230 V Version)
173
Work Surface for 6 Supply Units
174
Energy Connections Inside the Laboratory
174
Cooling Water Supply/Cooling Circuit
174
Process Gas Supply
174
Temperatures in the Univessel
175
Stirrer Drive
175
External Pumps
175
Ambient Conditions
176
Calculating Water Hardness
176
Dimensions of the Variable Area Flow Meters
177
Conformity & Licenses
178
GNU Licensing
178
Conformity Documents
178
Appendix
182
Pin Assignment Female Connectors
182
Decontamination Declaration
184

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