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Manuals and User Guides for COULTER HmX Hematology Analyzer. We have
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COULTER HmX Hematology Analyzer manual available for free PDF download: Reference Manual
COULTER HmX Hematology Analyzer Reference Manual (128 pages)
Brand:
COULTER
| Category:
Measuring Instruments
| Size: 1 MB
Table of Contents
Legal Notices
2
Revision Status
3
Table of Contents
5
Contents
6
Introduction
15
HOW to USE YOUR COULTER® Hmx HEMATOLOGY ANALYZER and Hmx HEMATOLOGY ANALYZER with AUTOLOADER DOCUMENTATION SET
15
About this Manual
15
Conventions
16
List of Icons
17
Computer Program Statement
17
1 Use and Function
19
Intended Use
19
General
19
Parameters
20
The Hmx Hematology Analyzer with Autoloader
20
CLIA Complexity Categories
21
Quality Control (Qc)
21
CLIA Complexity Table
21
Method History
22
Development
22
Hemoglobinometry
22
Analysis
23
Conductivity Analysis
23
Differential Measurement
23
Light Scatter Analysis
23
Reticulocyte (Retic) Analysis
23
Volume Analysis
23
System Components
24
Analyzer/Systems Control Module
24
Diluter
24
Electronic Power Supply
24
Main Unit
24
Pneumatic Power Supply
24
Sample Handler
24
Data Management System (DMS)
25
Options
25
Printers
25
Reagents
25
Diluent
25
System Version Display
25
CBC Lytic Reagent
26
Hmx PAK
26
Cleaning Agent
26
Pak Lyse
26
Pak Preserve
26
Reagent a
26
Reagent B
26
Reticprep™ Reagent Kit
26
Controls and Calibrator
27
Calibrator
27
Controls
27
Material Safety Data Sheets (Msds)
27
2 Installation
29
General
29
Special Requirements
29
Space and Accessibility
29
Electrical Input
29
Ambient Temperature and Humidity
30
Ventilation
30
Air Conditioning
30
Drainage
30
Date Format
31
Interunit Connections
31
Reagent and Waste Connections
31
Reagent and Waste Container Tubing Connections
32
Power and Signal Cables
33
The Hmx Hematology Analyzer
33
3 Operation Principles
35
General Principles
35
CBC Analysis
35
Differential Analysis
35
Coulter Method of Counting and Sizing
35
Effect of Reagents
36
Retic Analysis
36
SPECIMEN TRANSPORT - Hmx HEMATOLOGY ANALYZER with AUTOLOADER
37
Loading a Cassette
37
SPECIMEN TRANSPORT - Hmx HEMATOLOGY ANALYZER
38
Reading a Bar-Code Label
38
Sample Flow
39
Normal Sample Flow
39
Baths Draining
40
Erythrolyse II (PAK LYSE) and Stabilyse (PAK PRESERVE) Reagent Pumps
42
Aperture Baths and Vacuum Isolators
42
Retic Sample Flow
43
Sample Movement to the Flow Cell
43
Counting and Sizing
44
Coincidence Correction
44
Extended Counting
44
Red and White Blood Cell Counting
44
Routine Counting
44
Triplicate Counting/Voting
44
Plt Count and Size Distribution
45
Pulse Editing
45
RBC Count and Size Distribution
45
Sweep Flow
45
Differential-Related
46
Plt Fitting Process
46
Scatterplot Development
46
Scatterplot, DF 1 View
46
Retic-Related
47
Scatterplot, DF 2 View
47
Scatterplot, DF 3 View
47
Retic Parameters
48
Derived and Computed Parameters
48
Hgb CONCENTRATION MEASUREMENT
48
Parameters and Their Derivation
48
Scatterplot, DF 5 View
48
Scatterplot, DF 6 View
48
White Blood Cell (WBC) Count
49
Red Blood Cell (RBC)
49
Hemoglobin (Hgb) Concentration
49
Mean Corpuscular Volume (MCV)
49
Hematocrit (Hct)
49
Mean Corpuscular Hemoglobin (MCH)
49
Mean Corpuscular Hemoglobin Concentration (MCHC)
50
Red Distribution Width (RDW)
50
Platelet (Plt) Count
50
Mean Platelet Volume (MPV)
50
Differential Counts
50
Percentages
50
Absolute Numbers
51
Reticulocyte (Retic) Parameters
51
Reticulocyte Absolute Number (RET#)
51
Reticulocyte Percent (RET%)
51
4 Specifications/Characteristics
53
Instrument Specifications
53
Dimensions
53
Power
53
Consumption
53
Input - Dedicated Line
53
Installation Category
53
Pneumatic Supplies
53
Pressure
53
Vacuum
54
Temperature (Ambient Operating Range for Patient Samples)
54
Humidity
54
Recommended Reagents
54
Reagent Usage
54
Recommended Commercial Controls
54
Recommended Calibrator
54
Recommended Anticoagulant
55
Minimum Sample Volume Required
55
Tube Sizes for Closed-Vial Mode
55
Recommended Bar-Code Labels
55
DMS Storage
55
Controls
55
Patient Results
55
Conditions of Measurement
55
Hemoglobin Measurement
55
Aperture Size
56
Electronic Stability
56
Throughput
56
Software Specificatons
56
Date Format
56
Cbc and Differential Performance Specifications
56
Precision
56
Precision Specifications
56
Accuracy
57
Cbc
57
Linearity
57
WBC Differential
57
Precision, WBC Differential Parameters
57
CBC Accuracy Limits
57
Mode-To-Mode Matching
58
Background Counts
58
Linearity Limits
58
Background Counts for CBC Analysis
58
Carryover
59
Reticulocyte Performance Specifications
59
Accuracy
59
Precision
59
Flagging
60
Limitations
60
Operating Range
60
Reportable Range
60
PERFORMANCE CHARACTERISTICS - Hmx HEMATOLOGY ANALYZER
60
Precision of the CBC Parameters
60
Imprecision Analysis by Replication WHOLE BLOOD - Hmx Hematology Analyzer
61
Imprecision Analysis by Paired Sample - Hmx Hematology Analyzer
61
Accuracy of CBC Parameters
62
Imprecision Analysis (Diff Parameters) by Paired Sample - Hmx Hematology Analyzer
62
Imprecision Analysis (Diff Parameters) by Replication - Hmx Hematology Analyzer
62
Reference Range (Diff Parameters) for 160 Subjects - Hmx Hematology Analyzer
62
Accuracy of Differential Parameters
63
Clinical Sensitivity
63
Accuracy Analysis by Compared Specimens - Hmx Hematology Analyzer
63
Accuracy Analysis (Diff Parameters) by Compared Specimens - Hmx Hematology Analyzer
63
Flagging Criteria - H2O Method
64
Morphologic Abnormalities - Hmx Hematology Analyzer
64
Clinical Sensitivity for Morphologic Abnormals - Hmx Hematology Analyzer
64
PERFORMANCE CHARACTERISTICS - Hmx HEMATOLOGY ANALYZER with AUTOLOADER
65
Precision of the CBC Parameters
65
Precision of the Differential Parameters - Hmx Hematology Analyzer with Autoloader
65
Imprecision Analysis by Replication: WHOLE BLOOD - Hmx Hematology Analyzer with Autoloader
65
Imprecision Analysis by Paired Sample - Hmx Hematology Analyzer with Autoloader
65
Imprecision Analysis by Replication
65
Imprecision Analysis (Diff Parameters) by Paired Sample - Hmx Hematology Analyzer with Autoloader
66
Accuracy Analysis by Compared Specimens - Hmx Hematology Analyzer with Autoloader
66
Reticulocyte Performance Characteristics
67
Accuracy
67
Imprecision Analysis by Replication
67
Imprecision Analysis by Paired Samples
67
Accuracy Analysis by Compared Specimens
67
Reference Interval
68
Interfering Substances
68
Hgb
68
MCV
68
Rbc
68
Rdw
68
Reference Intervals
68
Plt
69
Mpv
69
Hct
69
Mch
69
Mchc
69
Diff Parameters
69
Reticulocytes
69
5 Laser Safety
71
Laser Safety Precautions
71
General Laser Safety Warnings
71
Warning Labels
71
Laser Safety Label
72
Safety Labels on the TTM
73
Laser Safety Labels for Bar-Code Reader on the Hmx Hematology Analyzer
74
Laser Safety Labels for Bar-Code Reader on the Hmx Hematology Analyzer with Autoloader
74
6 Reporting Options
75
Ticket Format on a Graphic Printer
75
Ticket Format
75
Graphic Format
76
Graphic (Narrow/Small Page) Format
76
7 Bar-Code Specifications
79
Bar-Code Labels
79
Optical Characteristics at 670 Nm ±10
80
Label Specifications
81
Bar-Code Label Specifications
81
Code-Related Specifications
82
Printing Methods
82
Bar-Code Reader
82
Description
82
Settings and Defaults
82
Bar-Code Reader Settings and Defaults
82
Bar-Code Decoder
83
Hmx Hematology Analyzer
83
Hmx Hematology Analyzer with Autoloader
83
Normal Operation
83
Sample Tube Sizes
85
Beckman Coulter
85
Becton Dickinson
85
Worldwide
85
U.s.a
85
Europe
86
U.K. and Australia
86
Japan
86
Greiner
86
Vacuette Brand
86
Johns
87
Labco
87
Exetainer Brand
87
Labo Express Service (L.e.s
87
Ldm
87
L.I.p
87
Sarstedt
87
Sherwood Medical
88
TERUMO (Worldwide
88
Diff Comparison
89
Introduction
89
Procedure
89
Log Sheets
93
Limited Warranty
97
Index
111
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