Download Print this page

Arrayit NanoPrint LM60 User Manual

Microarray printers

Advertisement

NanoPrint™ Enterprise Level LM60 and LM210
Microarray Printers
Users Manual
v.130710.1

Advertisement

loading
Need help?

Need help?

Do you have a question about the NanoPrint LM60 and is the answer not in the manual?

Questions and answers

Summary of Contents for Arrayit NanoPrint LM60

  • Page 1 
 
 
 
 NanoPrint™ Enterprise Level LM60 and LM210 Microarray Printers Users Manual v.130710.1...
  • Page 2 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 3: Table Of Contents

    Software Features – page 7 System Options and Advantages – page 8 System Specifications and Features – page 9 System Installation and Performance – page 14 Ordering Information – page 22 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 4: Introduction

    Arrayit NanoPrint™ robots move with 500 nanometer resolution and deliver sub-nanoliter sample volumes using high throughput, patented contact printing devices. Arrayit printing devices are covered by U.S. Patent 6,101,946 and these devices require a license for diagnostic applications. Please contact us for licensing information regarding diagnostic microarray manufacturing.
  • Page 5: System Overview

    Figure 2. Shown is the NanoPrint™ LM210 system with a capacity of three 384-well sample microplates printing onto 210 standard glass slide substrates. 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 6 NanoPrint™ Microarrayers are industrial-level platforms for all microarray manufacturing applications including DNA microarrays, protein microarrays, and other types of biomolecules. NanoPrint™ systems enable the manufacture of microarrays utilizing ArrayIt® Professional, Stealth Style Micro Spotting Pins. The NanoPrint™ uses superior linear drive motion control technology...
  • Page 7: Software Features

    Combined with the compact bench top design, user configurable worktable, humidity and particulate control, a host of available options, and the flexible and sophisticated software, NanoPrint™ systems offer the complete solution to high performance microarray printing. 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 8: System Options And Advantages

    • Superior Accuracy • Near maintenance-free operation • High speed • High load capacity • Zero "sagging" with loss of power • Safer and much more durable than stepper motors • 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 9: System Specifications And Features

    Series Pins and Printheads. Destination Microarray substrates, glass slides, microplates, custom Printing technology Arrayit Pro, 946 or Stealth pins and printheads Number of pins Configurable 1 to 48 at 4.5 mm centers or 1 to 192 at 2.25mm Spot diameter...
  • Page 10 Systems sensors prevent splashing and overflowing for pin and deck safety. Drying is accomplished by vacuum using a quiet but powerful ACM-controlled function. The Pin Cleaning Module is rugged, durable and 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 11 The humidification and dehumidification systems are triggered by sensors that automatically maintain the levels set by the user. 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 12 Shown here is a screen shot of the interstitial printing software command that automatically directs the robot to deposit the printed spots into a “orange packing” configuration for dramatically increased microarray printing density. 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 13 Optimal parameters are set at the factory but can be easily changed by the user for printing onto many different surfaces. 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 14: System Installation And Performance

    The screenshot shows a worktable allowing printing into 15 microplates (96-well) for the NanoPrint™ LM60. 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 15 Figure 4. Data showing the printing consistency of eight different SMP3B pins in a single print run using the NanoPrint LM60. The data were provided courtesy of W.G. Shreffler and L. Bardina at the Mount Sinai School of Medicine (New York, USA).
  • Page 16 Figure 5. Shown is the NanoPrint™ LM210 system configured in an ArrayIt® class 100 cleanroom. The entire deck is accessible via two doors that open and close independently for user convenience and safety. The top of the Accessory Control Module (ACM) is shown beneath the robot.
  • Page 17 Figure 6. Shown is the NanoPrint™ LM210 system configured in an ArrayIt® class 100 cleanroom. Microarray manufacturing parameters including the number of pins, substrates, spots, technical replicates, printing pattern, worktable, printing offsets, speed, acceleration, and many other technical aspects are completely controllable by the operator via an intuitive graphical user interface (GUI).
  • Page 18 Professional, 946 or Stealth series. The attachment bayonet allows the printhead to be attached and removed for cleaning easily and precisely, eliminating the need for system re-calibration. 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 19 500 nanometer increments for unsurpassed printing precision at speeds of 48 spots per second. A total of 48 microarray printing pins of any tip size from the Professional, 946 or Stealth series may be used on our NanoPrint™ systems. 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 20 With a capacity of 60 worktables, the WorkTable Workstation allows fully automated printing onto 1800 glass substrates, 300 96-well microplates, or 900 custom cassettes by special purchase quoted separately from standard NanoPrint configurations. 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 21 NanoPrint™. This format is compatible with the AHC4x24, AHC1x24, and RC1x24 hybridization reaction tools. Using this format and an NanoPrint™ LM210 Microarrayer enables the automated manufacturing of more than 5,000+ microarrays per run and 1,400+ using a NanoPrint™ LM210. 
 Copyright 1993-2013 Arrayit Corporation. All rights reserved. 7/10/13...
  • Page 22: Ordering Information

    WARP1 controllers on all three NanoPrint™ axes for sub-micron positional control. Each system LM60 is equipped with Arrayit’s patented contact printing LM60 $125,475 Microarrayer technology, full environmental control and highly intuitive software GUI. The standard LM60 worktable prints from 384-well microplates using 48 pins onto 60 glass substrates.
  • Page 23 NanoPrint™ microarrayers are configured individually for each customer based on the number and type of printing pins, deck configuration, and options. *Please contact us by telephone 408-744-1331, fax 408-744-1711, email arrayit@arrayit.com, or click on the purchase buttons above to proceed directly to the purchase page.

This manual is also suitable for:

Nanoprint lm210