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MannKind Afrezza Getting Started

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Inhalation Powder
Actual Size
G E T T I N G S T A R T E D
W I T H A F R E Z Z A
®
THE ONLY ULTRA RAPID-ACTING INHALED MEALTIME INSULIN FOR
ADULTS LIVING WITH TYPE 1 OR TYPE 2 DIABETES
Please see Important Safety Information on page 16-17, and see Medication Guide, including BOXED WARNING, and
Instructions for Use in pocket. Visit www.afrezza.com/safety to see the Full Prescribing Information.

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Summary of Contents for MannKind Afrezza

  • Page 1 THE ONLY ULTRA RAPID-ACTING INHALED MEALTIME INSULIN FOR ADULTS LIVING WITH TYPE 1 OR TYPE 2 DIABETES Please see Important Safety Information on page 16-17, and see Medication Guide, including BOXED WARNING, and Instructions for Use in pocket. Visit www.afrezza.com/safety to see the Full Prescribing Information.
  • Page 2 • It is not known if AFREZZA is safe and effective for use in people What should I avoid while using AFREZZA? who smoke. AFREZZA is not for use in people who smoke or have While using AFREZZA do not: recently stopped smoking (less than 6 months).
  • Page 3 As someone living with type 1 or type 2 diabetes who depends on mealtime insulin, you know how important flexibility can be. Afrezza is the only ultra-rapid acting inhaled insulin that works on your schedule to deliver mealtime management in the moment.
  • Page 4 Scar tissue can affect the body’s ability to absorb insulin and can ■ cause serious complications. Since Afrezza leaves the body quickly within 1.5 to 3 hours,† depending on the dose, it gives you the option to take additional correction doses at 1 and 2 hours after meals, if needed.
  • Page 5 UNITS QUICK TIP Afrezza® is available in 4-, 8- and 12-unit color-coded cartridges. If needed, you can combine cartridges to take your prescribed dose. For example, two 8-unit cartridges provide a dose of 16 units of Afrezza. Please see Important Safety Information including BOXED WARNING on pages 16-17.
  • Page 6 2 hours after beginning of the meal. QUICK TIP Afrezza® is available in 4-, 8- and 12-unit color-coded cartridges. If needed, you can combine cartridges to take your prescribed dose. For example, two 8-unit cartridges provide a dose of 16 Afrezza units.
  • Page 7 You may need to adjust DOSE your dose, up or down, based on your blood sugar levels and how Afrezza works for you. TYPICAL DOSING AT MEALTIME In Afrezza clinical trials, the range of average dose per meal was 12-16 Afrezza Units.
  • Page 8 AFREZZA cartridges should line up with the pointed trip If your prescribed AFREZZA dose is more than 12 units you will need to use more than 1 cartridge to get your right dose. needed for your dose. end in the inhaler.
  • Page 9 OPEN INHALER: Open the inhaler by lifting the white mouthpiece ■ 4 units to a vertical position. Before you put the AFREZZA cartridge in your Open Inhaler inhaler, make sure it has been at room temperature for 10 minutes. Open the inhaler by lifting...
  • Page 10 (this will nhaler. and tilt the inhaler down Since Afrezza is an inhaled powder, it is not uncommon to experience cough at the beginning of your treatment. In our clinical open the drug cartridge). towards your chin, as shown.
  • Page 11 A small amount of powder residue in the mouthpiece or cartridge is normal. This does not affect your dose. You can wipe the Close your lips around the r is closed. mouthpiece to form a seal. mouthpiece with a clean, dry cloth to remove moisture or lipstick. Do not wash the Afrezza inhaler. Tilt the inhaler downward while keeping your head level.

  • Page 12: Storage And Handling

    STORAGE AND HANDLING HOW TO TAKE CARE OF YOUR AFREZZA INHALER AND INSULIN CARTRIDGES NOT IN USE: REFRIGERATED STORAGE USE: ROOM TEMPERATURE STORAGE Reference the chart below for instructions on Store unopened drug taking care inhaler and opened foil packages.
  • Page 13 Here’s a step-by-step guide to filling your first Afrezza prescription: ® Before you visit the pharmacy, be sure to download your Afrezza Savings Card at www.AfrezzaSavingsCard.com Take both your prescription and savings card to the pharmacy, and be prepared to give them at least 48 hours to fill...
  • Page 14 *See program details at afrezza.com/savings-program. Eligibility criteria and maximum benefit limitations apply. Your healthcare team will most likely need to get an approved Prior Authorization for Afrezza before you can use your savings card to fill your prescription. Please see Important Safety Information including BOXED WARNING on pages 16-17.
  • Page 15 Monday - Friday 11:00am - 7:00pm EST MannKind Training AFREZZA TRAINING CALL CENTER Press the appropriate number to be transferred to our Do you need training on how to use Afrezza Afrezza Training Call Center. or need an Afrezza refresher training? HOURS Monday - Friday 9:00am - 6:00pm EST *Eligibility criteria and maximum benefit limitations apply.

  • Page 16: Frequently Asked Questions

    FREQUENTLY ASKED QUESTIONS Q: WHEN SHOULD I TAKE MY AFREZZA®? Afrezza should be inhaled at the beginning of a meal because it closely mimics natural insulin response. Q: IS IT NORMAL TO SEE POWDER LEFT OVER IN MY INHALER AFTER I’VE INHALED MY AFREZZA DOSE? Yes, a small amount of powder residue in the mouthpiece or cartridge is normal.

  • Page 17: Important Safety Information

    • It is not known if AFREZZA is safe and effective for use in people who smoke. AFREZZA is not for use in people who What should I avoid while using AFREZZA? smoke or have recently stopped smoking (less than 6 months).
  • Page 18 There of your face, tongue, or throat, sweating, extreme drowsiness, were too few cases to know if lung cancer was related to AFREZZA. If dizziness, confusion. you have lung cancer, you and your healthcare provider should decide if you should use AFREZZA.
  • Page 19 Inhalation Powder AFREZZA, the Afrezza logo, AFREZZAASSIST and logo, MANNKIND and MANNKIND CARES are registered trademarks of MannKind Corporation. © MannKind Corporation May, 2024. US-AFR-2520.