Honda Civic 2021 Owner's Manual page 580

uuIf a Tire Goes FlatuChanging a Flat Tire
U.S. models
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TPMS and the Compact Spare Tire
If you replace a flat tire with the spare tire, the low tire pressure/TPMS indicator
comes on while you are driving. After driving for a few miles (kilometers), Tire
Pressure Monitor Problem will appear on the driver information interface and the
indicator will start blinking for a short time and then stay on; however, this is normal
and is no cause for concern.
Calibrate the TPMS when you replace the tire with a specified regular tire.
2 TPMS Calibration P. 443
579