Indus MouseMonitor User Manual

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INDUS

I N S T R U M E N T S

MouseMonitor™

User's Guide

Heart Rate

•

Respiration

•

ECG

•

Temperature

•

Warming

www.mousemonitor.com

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Summary of Contents for Indus MouseMonitor

Page 1 INDUS I N S T R U M E N T S MouseMonitor™ User’s Guide Heart Rate • Respiration • • Temperature • Warming www.mousemonitor.com...
Page 2 TABLE OF CONTENTS INTRODUCTION PACKING LIST SYSTEM SETUP EXPERIMENTAL SETUP OPERATING INSTRUCTIONS INPUT AND OUTPUT CONNECTORS DISPLAYS AND BUTTONS MOUSEMONITOR SETTINGS STUDY PRESETS INFORMATION DISPLAY WAVEFORM NUMERIC COMMENTS HELP ADVANCED ELECTRODES FILTERS & SCALING ADVANCED RESPIRATION ELECTRODES FILTERS & SCALING...
Page 3 TABLE OF CONTENTS ANALOG OUTPUT MODULE CHANNEL ASSIGNMENT FILTERS & SCALING PULSE OXIMETER MODULE SENSORS FILTERS & SCALING 10.1” TOUCH DISPLAY QUICK REFERENCE 10.1” TOUCH DISPLAY WI-FI CONFIGURATION TEMPERATURE CONTROL OPERATION TECHNICAL SPECIFICATIONS REVISION HISTORY OTHER PRODUCTS...
Page 4 INTRODUCTION The MouseMonitor is a compact heated surgical platform that displays ECG, respiration and plethysmogram waveforms as well as heart rate, breath rate, core temperature and SpO2. The unique integrated operating platform supports magnetic accessories and incorporates ultra-low noise, high-resolution ECG electronics and intelligent zone heating with a durable surgical stain- less steel top.
Page 5 MouseMonitor Module Connection Cable (USB Type A to USB Type B) Note: Replacement cables, ECG electrode crème and rat, mouse & neonatal mouse rectal temperature probes can be purchased from Indus Instruments. Contact us at +1 (281) 286-1130 or email us at sales@indusinstruments.com for pricing.
Page 6 MOUSEMONITOR ASSEMBLED UNIT SETUP Display Unit Connections: 1. MouseMonitor Data Cable Connector (Packing List Item #6) 2. Display Unit Power Supply Connector (Packing List Item #5)
Page 7 4. MouseMonitor Module Connector 5. MouseMonitor Module Connector 6. MouseMonitor Module Connector 7. MouseMonitor Data Cable (Packing List Item #6) 8. Heated Surgical Platform Power Supply (Packing List Item #3) Heated Surgical Platform Front Connectors: 9. External Electrode Connector, Right Upper Limb (Packing List Item #9) 10.
Page 8 Experimental Setup of MouseMonitor for Mice Supine Prone Supine position Cranial, head towards operating platform top Caudal, tail towards operating platform top Prone position Cranial, head towards operating platform top Caudal, tail towards operating platform top...
Page 9 Experimental Setup of MouseMonitor for Rats Supine Prone Supine position Cranial, head towards operating platform top Caudal, tail towards operating platform top Prone position Cranial, head towards operating platform top Caudal, tail towards operating platform top...
Page 10 (Ex. ECG Lead I & ECG Lead III will have the same vertical scaling). Horizontal pinch in chart area changes time scaling. All waveforms have the same horizontal time scale. Touch the PAD TEMPERATURE button on the right of the screen to go to MouseMonitor SET- TINGS - HOMEOTHERMIC HEATER.
Page 11 INPUT AND OUTPUT CONNECTIONS POWER SUPPLY CONNECTION The MouseMonitor heated surgical platform utilizes a universal switching power supply that op- erates between 100-240VAC, 50-60Hz for convenient worldwide operation. DATA CONNECTION The MouseMonitor heated surgical platform connects to the MouseMonitor Display Unit with a custom USB cable.
Page 12 DISPLAYS Waveform Display Numeric Display • Heart Rate (Lead I) 200-999BPM • ECG Lead I (LA-RA) • Heart Rate (Lead II) 200-999BPM • ECG Lead II (LL-RA) • Heart Rate (Lead III) 200-999BPM • ECG Lead III (LL-LA) • Respiration Rate 60-300BrPM •...
Page 13 SETTINGS - STUDY - PRESETS Presets - Multiple researchers can save their preferred settings as a preset proﬁ le for easy re- trieval at a later date. This way multiple researchers can share a single MouseMonitor and each researcher can have their preferred setup.
Page 14 SETTINGS - STUDY - INFORMATION • Study Name - Touch to type your custom study name with the on-screen keyboard. • Animal Identiﬁ er - Touch to type your custom animal ID with the on-screen keyboard. • File Name - Touch to type your custom ﬁ le name with the on-screen keyboard. All screenshots and recordings will use study name, animal ID, ﬁ...
Page 15 Note: If you want to change the conﬁ guration of the waveform display area you will need to con- ﬁ gure the Waveform Assignment Drop Menus as desired, then tap OK to exit settings and return to the MouseMonitor App. Exit and re-open the MouseMonitor App for the waveforms to display properly.
Page 16 Note: If you want to change the conﬁ guration of the numeric panels you will need to conﬁ gure the Numeric Panel Drop Menus as desired, then tap OK to exit settings and return to the Mouse- Monitor App. Exit and re-open the MouseMonitor App for the numeric panels to display prop- erly.
Page 17 SETTINGS - COMMENTS The comments tab allows you to store 7 custom pre-deﬁ ned comments that you can quickly place during experiments. There is also a custom comment option that can be entered during the ex- periment with any comment text. Comments are placed when OK is pressed from inside the comment menu and can be viewed when the saved recordings are opened.
Page 18 +1 (281) 286-1130 or sales@indusinstruments.com if you have any questions or concerns. The MouseMonitor was developed through close collaborations between Indus Instruments and our customers; we rely on your feedback to further reﬁ ne our products as well as get new ideas for...
Page 19 SETTINGS - ADVANCED • Test Signal - Can be set to None, Hardware, 10Hz, 50Hz, 60Hz, 100Hz, and 1000Hz or Simulated ECG. Simulated ECG is a set of mouse signals captured in a lab. • Enable Logging - Records all application and Android events to a log ﬁ le for troubleshooting. The factory setting for this is off.
Page 20 Horizontal Orientation - Conﬁ gure the direction of the animal’s chest (Prone, Supine or Cus- tom). External Electrodes - The MouseMonitor ships with a set of needle electrodes that can be used on a wide variety of animals. Other electrodes are available including: •...
Page 21 SETTINGS - ECG-FILTERS & SCALING ECG Filters: • The High Pass Filter can be set to off, 0.2Hz, 0.5Hz, 1Hz, 2Hz, 5Hz, or 10Hz. • The Low Pass Filter can be set to off, 30Hz, 100Hz, 200Hz, 500Hz, or 1000Hz. •...
Page 22 SETTINGS - ECG - ADVANCED ECG Front-end Gain: The factory setting is 6. If you have a particular application that could beneﬁ t from a different ECG Front-end Gain setting please call us before changing this value. Available gain settings are 6, 1, 2, 3, 4, 8 and 12.
Page 23 Horizontal Orientation - Conﬁ gure the direction of the animal’s chest (Prone, Supine or Cus- tom). External Electrodes - The MouseMonitor ships with a set of needle electrodes that can be used on a wide variety of animals. Other electrodes are available including: •...
Page 24 SETTINGS - RESPIRATION-FILTERS & SCALING Respiration Filters: • The High Pass Filter can be set to off, 0.2Hz, 0.5Hz, 1Hz, 2Hz, 5Hz, or 10Hz. • The Low Pass Filter can be set to off, 1Hz, 2Hz, 5Hz, 10Hz, or 20Hz. •...
Page 25 SETTINGS - RESPIRATION - ADVANCED Disable Respiration - Allows you to turn off the Impedance Pneumography injected current signal. Transmit Raw Data - Allows you to view/record the unprocessed respiration signal. Analog Ground: This allows you to connect the power supply ground to different sources. The factory setting is to connect the analog ground to isolated ground, this typically provides the best performance in most environments.
Page 26 SETTINGS - HOMEOTHERMIC HEATER Heater Settings: Touch (+) or (-) to adjust temperature. Maximum temperature setting is 42°C. You can disable the heater if your experiment requires this or you’re working with larger animals and don’t require heat.
Page 27 SETTINGS - CORE TEMPERATURE Thermocouple Status: Indicates whether a working temperature probe is connected.
Page 28 Note: If you want to change the conﬁ guration of the waveform output you will need to conﬁ gure the Channel Assignment Drop Menus as desired, then tap OK to exit settings and return to the MouseMonitor App. Exit and re-open the MouseMonitor App for the waveforms to output prop- erly.
Page 29 SETTINGS - ANALOG OUTPUT - FILTERS & SCALING Analog Output Filters: • The High Pass Filter can be set to off, 0.2Hz, 0.5Hz, 1Hz, 2Hz, 5Hz, or 10Hz. • The Low Pass Filter can be set to off, 1Hz, 2Hz, 5Hz, 10Hz, 20Hz, 30Hz, 100Hz, 200Hz, 500Hz, or 1000Hz.
Page 30 SETTINGS - PULSE OXIMETER - SENSORS Coming Soon!
Page 31 SETTINGS - PULSE OXIMETER - FILTERS & SCALING Coming Soon!
Page 32 10.1” TOUCH DISPLAY QUICK REFERENCE FRONT BACK BOTTOM LEFT RIGHT...
Page 33 SETTING UP WI-FI Touch the APPS icon. Then swipe to the second screen, and touch the SETTINGS icon, the WIRELESS & NETWORKS icon, Wi-Fi SETTINGS, and then Wi-Fi, if not turned on. The device scans for and displays all available Wi-Fi networks. Touch the Wi-Fi network you want to connect to.
Page 34 External environmental conditions such as room temperature and drafts from air conditioners or fans can have an impact on the MouseMonitor control system and it may not be able to attain the desired temperature. If the actual temperature is consistently a degree or more below the set temperature this is a good indication that there is a large amount of heat loss (pos- sibly because of an air draft).
Page 35 TECHNICAL SPECIFICATIONS Physiological Intuitive Touch Interface Parameters 10.1” Touch Screen Capacitive touch screen works with surgical gloves. • Ultra low-noise, high-resolution • Simultaneous Lead I, II & III Ergonomic Display • 24-bit sigma-delta AD converters Waveforms and numeric data presented in an easily Heart Rate readable format.
Page 36 TECHNICAL SPECIFICATIONS The MouseMonitor is a compact heated surgical platform that displays ECG, respiration and plethysmogram waveforms as well as heart rate, breath rate, core temperature and SpO2. The unique integrated operating platform supports magnetic accessories and incorporates ultra- low noise, high-resolution ECG electronics and intelligent zone heating with a durable surgical stainless steel top.
Page 37 REVISION HISTORY HISTORY REV: 1.0 Release...
Page 38 High-Resolution Pulsed Doppler Ultrasound MouseDoppler™ 20MHz Ultrasound • Real-Time • Cardiovascular Spectrograms Pulse Wave Velocity Versatile Powerful Software High-Resolution Quantify vascular stiffness & A wide selection of Real-time spectrogram Can capture mouse distensibility for aging ultrasound transducers acquisition; data analysis & coronary artery ﬂ...
Page 39 Non-invasively Measure Mouse MCA Blood Flow The MouseDoppler is a real-time pulsed Doppler spectrogram acquisition and data analysis tool designed speciﬁ cally for measuring cardiovascular function in mice and rats. The high sam- pling rates and excellent temporal resolution are ideal for working with the elevated heart rates, rapid blood accelerations and high blood velocities present in mice.
Page 40 MouseDoppler Speciﬁ cation Sheet The MouseDoppler is a real-time pulsed Doppler spectrogram acquisition and data analysis tool designed speciﬁ cally for measuring cardiovascular function in mice and rats. The high sam- pling rates and excellent temporal resolution are ideal for working with the elevated heart rates, rapid blood accelerations and high blood velocities present in mice.
Page 41 10MHz Pulsed Doppler Module Speciﬁ cations Ultrasound Frequency 10MHz, crystal controlled Phasic Output Filter Three position switch Pulse Repetition Frequency 31.25 or 62.5kHz Phasic One pole at 60Hz Transmitter Pulse Width 0.8μs Damped One pole at 15Hz Receiver Pulse Width 0.4μs Mean Two poles at 0.25Hz...
Page 42 I N S T R U M E N T S 721 Tristar Drive 721 Tristar Drive Webster, TX 77598, USA Webster, TX 77598, USA Tel: +1 (281)-286-1130 Tel: +1 (281)-286-1130 Fax: +1 (281)-461-8168 Fax: +1 (281)-461-8168 sales@indusinstruments.com info@indusinstruments.com www.mousemonitor.com www.indusinstruments.com...