MSD MESO QuickPlex SQ 120 Instrument Manual
  1. Manuals
  2. Brands
  3. MSD Manuals
  4. Laboratory Equipment
  5. MESO QuickPlex SQ 120
  6. Instrument manual

MSD MESO QuickPlex SQ 120 Instrument Manual

Hide thumbs
Table of Contents

Advertisement

Quick Links

Download this manual
INSTRUMENT MANUAL
MESO
®
QuickPlex SQ 120
ww w.m es os c ale.com
®

Advertisement

Table of Contents
loading
Need help?

Need help?

Do you have a question about the MESO QuickPlex SQ 120 and is the answer not in the manual?

Questions and answers

Subscribe to Our Youtube Channel

Related Manuals for MSD MESO QuickPlex SQ 120

Summary of Contents for MSD MESO QuickPlex SQ 120

  • Page 1 INSTRUMENT MANUAL MESO ® QuickPlex SQ 120 ww w.m es os c ale.com ®...
  • Page 2 No part of this Manual may be duplicated, reproduced, stored in a retrieval system, translated, transcribed, or transmitted in any form or by any means without the express prior written permission of MSD. This Manual shall be returned to MSD within two (2) business days following any request by MSD.

  • Page 3: Table Of Contents

    System Description ..............................18 Intended Use ..............................18 Specifications Overview ..........................18 Plate Compatibility ............................18 System Components ............................. 18 MESO QuickPlex SQ 120 Instrument ......................19 3.5.1 CCD Camera and Telecentric Lens ....................20 3.5.2 Motion Control System ........................20 3.5.3...
  • Page 4 Preventive Maintenance ..........................34 Appendix ................................36 Troubleshooting Guide ..........................36 Specifications .............................. 38 6.2.1 MESO QuickPlex SQ 120 Instrument Specifications ................. 38 6.2.2 MSD Plate Specifications ....................... 39 Technical Support ..............................41 Bug Reports and Suggestions ........................41 Problems Running the QuickPlex SQ 120 ...................... 41...
  • Page 5 Figure 3:1 The QuickPlex SQ 120 imager and computer ....................19 Figure 3:2 Cutaway view of the imager ..........................20 Figure 3:3 MSD and custom barcode label locations ......................21 Figure 3:4 Custom Barcode Reader Selection Dialog ......................21 Figure 3:5 Status LEDs ..............................22 Figure 3:6 Power switch, power entry port, and USB port on the back of the instrument .............
  • Page 6 Introduction...

  • Page 7: Introduction

    MSD develops, manufactures, and markets detection instrument systems as well as a line of assay kits for use with these instruments, a proprietary line of reagents, and custom microplate printing and assay development services. MSD ®...

  • Page 8: Warnings And Caution Symbols

    Warnings and Caution Symbols WARNING General warnings advise operators of potential hazards and highlight the procedures or information necessary to avoid personal injury during use of the QuickPlex SQ 120 instrument. Symbol Explanation Risk exists for a mechanical, chemical, or safety hazard Risk exists for an electrical hazard Risk of exposure to biohazards CAUTION...
  • Page 9 Safety Information...

  • Page 10: Safety Information

    2.1.1 The MESO QuickPlex SQ 120 is classified per CFR Title 21 part 1040.10 and part 1040.11 as a Class 1 laser product with a built-in barcode reader classified as Class 2. The QuickPlex SQ 120 is classified as Class 1 in accordance with IEC 60825-1:2014.

  • Page 11: Hazardous Substances

    In accordance with People’s Republic of China Order No. 32 of the Ministry of Industry and Information Technology (Management Methods for the Restriction of the Use of Hazardous Substances in Electrical and Electronic Products), MSD has designated an environmental protection use period of 50 years for the MESO QuickPlex SQ 120 instrument when used under normal operating conditions.

  • Page 12: General Operation

    Symbol/Label Description This symbol indicates placing a toggle switch in this position will place the instrument in a powered on state. This symbol indicates placing a toggle switch in this position will place the instrument in a powered off state. The European Conformity Marking indicates that the device complies with the essential requirements of the relevant European health, safety and environmental protection legislation, which includes compliance with the Restriction of Hazardous Substances (RoHS 2) directive.

  • Page 13: Hazards

    For best performance, remove any sample or reagent spillage from the instrument. For safety, the operator should power down the instrument and disconnect the QuickPlex SQ 120’s power cord prior to cleaning near moving parts. For significant spills or liquid intrusion into the instrument enclosure (e.g., resulting from a fire protection water sprinkler), contact MSD Instrument Service.

  • Page 14: Chemical And Biological

    Although the QuickPlex SQ 120 uses a 24 volt DC power supply, laboratory personnel should never remove any instrument covers that would expose electrical circuits. Only authorized MSD Service personnel should perform repairs to the interior of the QuickPlex SQ 120.

  • Page 15: Mechanical

    The QuickPlex SQ 120 instrument weighs 44.5 lbs. (20.2 kg.). Be careful to use proper technique when lifting it to minimize the risk of injury. Two or more people should lift from beneath the instrument. Please contact MSD Instrument Service before attempting to move the instrument.

  • Page 16: Software And Operating System Compatibility

    For the protection of future users and service personnel, please follow site safety procedures and the directions of the site safety officer to disinfect the QuickPlex SQ 120 instrument. If shipping to MSD, contact MSD Instrument Service to determine the level of decontamination required.
  • Page 17 System Description...

  • Page 18: System Description

    System Description Intended Use The MESO QuickPlex SQ 120 is for research use only. The instrument is not for use in diagnostic procedures. Specifications Overview The QuickPlex SQ 120 instrument offers high sensitivity and a dynamic range that exceeds 5 logs. The QuickPlex SQ 120 instrument is designed to read both SECTOR and QUICKPLEX plates.

  • Page 19: Meso Quickplex Sq 120 Instrument

    Figure 3:1 The QuickPlex SQ 120 imager and computer MESO QuickPlex SQ 120 Instrument The main components of the QuickPlex SQ 120 instrument (Figure 3:2) include: • CCD camera and telecentric lens • Plate motion control system (not shown) •...

  • Page 20: Ccd Camera And Telecentric Lens

    DISCOVERY WORKBENCH software to identify the plate type and to read and interpret the plate data correctly. For certain applications, users may be interested in applying custom barcode labels. Custom barcodes may be placed on the side of the plate next to the MSD barcode. Figure 3:3 illustrates where custom barcode labels may be placed.

  • Page 21: Integrated Assay Plate Stacker

    To enable custom barcode reading, open the instrument reader window, navigate to Tools  Instrument Configuration, and select Enable Long-side Custom Bar code Reader. Figure 3:4 Custom Barcode Reader Selection Dialog If you have questions concerning the use of custom barcodes on MSD plates, please contact MSD Scientific Support.

  • Page 22: Status Leds

    Status LEDs 3.5.5 The status LEDs built into the camera tower are used to indicate the operational mode of the imager (Figure 3:5). • Steady blue: Imager is in standby mode and is ready to read plates. • Blinking blue: Imager is currently reading a plate. •...

  • Page 23: Power Switch And Input/Output (I/O) Panel

    Power Switch and Input/Output (I/O) Panel 3.5.6 The on/off switch, power entry port, and a USB port for communication between the instrument and notebook computer are located on the back of the instrument. Typically, the instrument should be left powered-on to maintain camera temperature. WARNING: Only use cables and accessories supplied with the instrument.

  • Page 24: Microsoft Windows-Compatible Computer

    A notebook computer is configured by MSD for use with the instrument and comes preloaded with MSD DISCOVERY WORKBENCH Software. The notebook computer and its software are an integral part of the system and should only be modified by an MSD service engineer.

  • Page 25: Figure 3:9 Sector Plate Showing 24, 4-Well Sectors

    Figure 3:9 SECTOR plate showing 24, 4-well sectors 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Figure 3:10 Reading QUICKPLEX plates in sectors, 1 well at a time System Description...

  • Page 26: Reading Partial Plates

    To avoid interference from electrical transients, plug the notebook computer and the instrument into outlets on the same circuit. If an uninterruptible power supply (UPS) is available, plug the notebook computer and instrument into the battery backup outlets. Please contact MSD Scientific Support if you have questions or need assistance.
  • Page 27 Installation, Quick Start, and General Use...

  • Page 28: Installation, Quick Start, And General Use

    Installation A qualified MSD service engineer must install and configure the QuickPlex SQ 120 system before use. Installation includes setup, connection of the instrument to its computer, and verification that the system is functioning properly. Only the computer provided with the instrument and preconfigured by MSD should be used to operate the instrument.

  • Page 29: Start-Up

    (Figure 4:2) will display while the instrument is initializing. Figure 4:2 MSD DISCOVERY WORKBENCH splash screen If DISCOVERY WORKBENCH does not start automatically, double-click the MSD DISCOVERY WORKBENCH icon on the Windows desktop (Figure 4:3). Figure 4:3 MSD DISCOVERY WORKBENCH desktop icon Setup 4.2.2...

  • Page 30: Run

    Chamfered corners NOTE: If the instrument is unable to read the barcode on the electronic plate (or if no barcode label is present), the plate will be skipped and ejected from the instrument. Please contact MSD Scientific Support for assistance.

  • Page 31: Figure 4:6 Run Options Dialog Box

    Click OK. The plate read starts. View the status in the lower left region (Status bar) of the DISCOVERY WORKBENCH software to monitor progress. When the plate read is complete, the electronic plate is ejected to the output stack and Run is enabled again.

  • Page 32: Results

    The instrument can be integrated with a robotics system for loading and unloading plates using the Remote Instrument Mode, which allows the instrument to be used as a component through its remote interface. A remote instrument manual that provides descriptions of the commands recognized by the MSD software is available upon request. Contact Scientific Support for more information on robotics integration.
  • Page 33 Maintenance...

  • Page 34: Maintenance

    Preventive Maintenance MSD recommends at least one preventive maintenance visit per year for the QuickPlex SQ 120. Only MSD service engineers should perform standard preventive maintenance, which includes cleaning and lubricating all appropriate internal components. Service contracts are available through MSD.
  • Page 35 Appendix...

  • Page 36: Appendix

    Disable the antivirus program temporarily to see if that is the issue. There are The instrument failed to read the several methods: Incompatible anti-virus software has plate after clicking the Run button. Exclude the file: C:\Program Files (x86)\MSD Discovery been installed on the instrument Workbench\lib\prefs.properties from scanning. computer. Disable real-time scanning.
  • Page 37 QuickPlex SQ 120 camera will cool when starting a plate run. This is a normal function of turning on the instrument. to -25 °C before the instrument Restart the software. Check the temperature again. Contact MSD Scientific becomes operational. Support if the camera temperature is not dropping.

  • Page 38: Specifications

    Specifications MESO QuickPlex SQ 120 Instrument Specifications 6.2.1 All performance information given below, including standard signal levels, detection limits, dynamic range, and instrument noise, is based on 150 µL read volumes in 96-well MULTI-ARRAY plates using standard plate read parameters.

  • Page 39: Msd Plate Specifications

    MSD Plate Specifications 6.2.2 MSD plates are designed to comply with the mechanical dimensions of the proposed standards of the Society of Biomolecular Screening. Contact MSD Scientific Support for further details. MSD plate barcode labels conform to ISO/IEC 16388, Information technology – Automatic identification and data capture techniques –...
  • Page 40 Technical Support...

  • Page 41: Technical Support

    Technical Support MSD provides excellent and timely support for all authorized users of the QuickPlex SQ 120. We welcome and carefully consider all bug reports and suggestions for improvements to future versions. We will work with you to resolve any problems you may encounter.
  • Page 42 MESO SCALE DISCOVERY, MESO SCALE DIAGNOSTICS, MSD, MSD GOLD, DISCOVERY WORKBENCH, MULTI-ARRAY, MULTI-SPOT, QUICKPLEX, SECTOR, SECTOR PR, SECTOR HTS, SULFO-TAG, N-PLEX, R-PLEX, S-PLEX, T-PLEX, U-PLEX, V-PLEX, STREPTAVIDIN GOLD, MESO, www.mesoscale.com, SMALL SPOT (design), 96 WELL 1, 4, 7, 9, & 10-SPOT (designs), 384 WELL 1 & 4-SPOT (designs), MSD (design), N-PLEX (design), R-PLEX (design), S-PLEX (design), T-PLEX (design), U-PLEX (design), V-PLEX (design), It’s All About U, and SPOT THE DIFFERENCE are trademarks and/or service marks of Meso Scale Diagnostics, LLC.

Table of Contents