Mundipharma NYXOID Leaflet

What is Nyxoid?
Nyxoid contains the active substance naloxone. Naloxone
temporarily reverses the effects of opioids such as heroin,
methadone, fentanyl, oxycodone, buprenorphine and morphine.
Nyxoid is a single-dose nasal spray used for the emergency
treatment of opioid overdose or possible opioid overdose in
adults and adolescents over 14 years.
Nyxoid is not a substitute for emergency medical care.
Nyxoid should be carried by anyone at risk of overdosing on an
opioid. Carers such as close family or friends should know where
to find Nyxoid in case of emergency.
When to use Nyxoid?
If you know or suspect that someone has overdosed on an opioid
drug, use Nyxoid as described on the other side of this leaflet.
!
ALWAYS call an ambulance immediately, even if the person
wakes up — they may become unconscious again, and stop
breathing.
!
Take care: a person treated with Nyxoid may show acute
withdrawal symptoms, which can be dangerous.
If you carry Nyxoid?
Set an alert in your calendar for 1 month before your Nyxoid is
due to expire. Then arrange for a replacement.
How does Nyxoid work?
Nyxoid contains naloxone. Nyxoid works for a short time only
to reverse the effects of opioids while you wait for emergency
medical attention. Naloxone works by displacing opioid drug
molecules from their receptors in the brain and body.
Opioid overdose
Naloxone treatment
Opioid overdose Naloxone treatment
Opioid drugs Brain signals are Naloxone fits more
Opioid drugs Naloxone fits more
Brain signals are
fit into blocked. Breathing strongly in the
fit into blocked. Breathing strongly in the
receptors. slows and stops. receptors. Opioids
receptors. slows and stops. receptors. Opioids are
are temporarily
The person
The person becomes temporarily displaced
becomes displaced from
unconscious. from receptors.
receptors.
unconscious.
naloxone
naloxone
opioid
opioid
opioid receptors in brain and body
opioid receptors in brain and body
Quick reference
For full instructions, turn to the other side of the leaflet.
1
Check for signs of overdose
Check for signs of overdose
2
Call an ambulance
Call an ambulance
3
Give Nyxoid
Give Nyxoid
4
Put into recovery position
Put into recovery position
5 Monitor and give support
Monitor and give support
until the ambulance arrives
until the ambulance arrives
Give 2 Give 2nd dose of Nyxoid nd dose of Nyxoid
6
if no improvement after 2–3 minutes OR
if no improvement after 2–3 minutes
overdose symptoms come back
OR overdose symptoms come back
7
Take care for your personal safety:
Take care for your personal safety:
watch for acute withdrawal symptoms
watch for acute withdrawal symptoms
Brain signals
Brain signals
resume. The
resume. The
person can
person can
breathe again,
8
breathe again,
Dispose of used Nyxoid
Dispose of used Nyxoid
and wakes up.
and wakes up.
and get a replacement
and get a replacement
Mundipharma Pharmaceuticals Limited,
Millbank House, Arkle Road, Sandyford, Dublin 18, Ireland.
T +353 1 2063800 info@mundipharma.ie
Nyxoid ® is a registered trade mark of
Mundipharma Corporation Limited.
Date of prep: April 2018
Job code: IRE/NYXO-18015a(1)
Date of item: July 2020
This leaflet tells you:
How to recognise symptoms of an opioid overdose
l
What to do in the event of an opioid overdose
l
How to give Nyxoid
l
How to recognise acute withdrawal symptoms
l
For more information:
www.nyxoid.com
Visit
or scan QR code
There is also a
Quick Start Guide
on the back of the
Nyxoid container.