ThermoFisher Scientific CryoMed TSCM17MA Operating And Maintenance Instructions Manual
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ThermoFisher Scientific CryoMed TSCM17MA Operating And Maintenance Instructions Manual

Controlled-rate freezer
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Thermo Scientific
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CryoMed
Controlled-Rate Freezer
Operating and Maintenance Instructions
331486H01 • Revision A • 10/22/2020

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Summary of Contents for ThermoFisher Scientific CryoMed TSCM17MA

  • Page 1 Thermo Scientific CryoMed Controlled-Rate Freezer Operating and Maintenance Instructions 331486H01 • Revision A • 10/22/2020...
  • Page 2 IMPORTANT Read this instruction manual. Failure to follow the instructions in this manual can result in damage to the unit, injury to operating personnel, and poor equipment performance. CAUTION All internal adjustments and maintenance must be performed by qualified service personnel. Material in this manual is for informational purposes only.

  • Page 3: Table Of Contents

    Contents Models................. 1 Safety Precautions ............2 Handling Liquid Nitrogen .......... 3 Unpacking ..............5 Packing List ............. 5 Introduction ..............6 Intended Use............6 Control Panel ............6 Door Latch ............... 6 USB WiFi Dongle............6 Thermal Printer (Optional) ......... 6 Operating Standards ..........
  • Page 4 Profiles ..............24 Users ............... 28 Calibration..............29 Active Run Summary ........... 31 Initiate a Run ............31 Manual Override ............31 Stop a Profile Run ............ 32 Run Review.............. 32 Alarms ................. 34 General Alarm Guidelines ......... 34 Printer Set-Up.............. 37 Change the Paper ............
  • Page 5 Edit Screen .............. 54 Startup..............54 Error Messages ............58 Review Screen ............60 User Controls ............60 Options Screen ............62 Plot Colors ............... 62 Default Directories ............ 63 Users ............... 63 Status Bar ..............65 Help ................. 66 About ...............
  • Page 6 Thermo Fisher Scientific Controlled-Rate Freezer Warranty ..............82 Thermo Fisher Scientific International Controlled-Rate Freezer Dealer Warranty....83 Regulatory ..............84 21 CFR part 11 ............84 Contact Information ............ 85...

  • Page 7: Models

    Models The following table shows the different models covered in this Operating and Maintenance Manual. Table 1. Applicable Models Exterior Interior Chamber Dimensions Dimensions Printer Models Electrical Plug Type Volume W x H x D in. W x H x D in. Options (cm) (cm)

  • Page 8: Safety Precautions

    Safety Precautions In this manual, the following symbols and conventions are used. WARNING: This symbol when used alone CAUTION: This symbol indicates surfaces which indicates important operating instructions which may become hot during use and may cause a reduce the risk of injury or poor performance of burn if touched with unprotected body parts.

  • Page 9: Handling Liquid Nitrogen

    Note: Because argon is an inert gas whose physical Handling Liquid Nitrogen properties are very similar to those of nitrogen, the precautions and safe practices for handling and use of liquid argon are the same as those for liquid nitrogen. WARNING: Contact of liquid nitrogen or cold Use containers designed for low temperature liquids.
  • Page 10 death. Use of oxygen monitoring equipment is strongly recommended. Note: The cloudy vapor that appears when liquid nitrogen is exposed to the air is condensed moisture; not the gas itself. The issuing gas is invisible. Never dispose of liquid nitrogen in confined areas or places where others may enter.

  • Page 11: Unpacking

    Unpacking At delivery, examine the exterior for physical damage while the CAUTION: Do not rest the unit on its back as it carrier’s representative is present. If exterior damage is may damage the plumbing or plastic heat break. present, carefully unpack and inspect the unit and all accessories for damage.

  • Page 12: Introduction

    Introduction ON/OFF Intended Use The right side of the unit is equipped with an ON/OFF switch Thermo Scientific CryoMed Controlled-Rate Freezers are as shown in Figure 2. used for the preparation of samples for storage at ultra-low or cryogenic temperatures (-80°C to -196°C) to support medical applications.

  • Page 13: Operating Standards

    Operating Standards These units are designed to operate under the following environmental conditions: • Indoor use • Altitude up to 2000 m • Ambient temperature: 15°C to 35°C • Humidity: 20%~85%, non-condensing • Mains Supply Fluctuations: ±5% of nominal for better performance •...

  • Page 14: Installation

    Installation and the exhaust vent on the left side of the unit. Refer to WARNING: Nitrogen gas can cause suffocation Figure 3 for rear side connections. without warning. Store and use liquid nitrogen only in a well-ventilated place. As the liquid WARNING: Do not block nor tamper with the evaporates, the resulting gas displaces the exhaust vent opening! Provide ample clearance...

  • Page 15: Ln 2 Connections

    Connections Sample Thermocouple Connection CAUTION: The flair connections on the ends of the transfer hose do not require any sealant. Pipe 1. Open the unit door. ® dope or Teflon tape may cause contamination of the liquid fill solenoids or leaks at the hose 2.

  • Page 16: Start Up

    Start Up Power-Up 1. Turn on the Controlled-Rate Freezer power switch on the right side of the unit. 2. The startup screen will be displayed. 3. Wait for the Start Setup button to appear. Figure 5. InstrumentConnect Screen Note: The LED to the right of the UI should be green. Note: Users outside U.S.A, Canada and Europe cannot access Connectivity with WiFi dongle.

  • Page 17: Initial Start Up

    Initial Start Up To start up the Controlled-Rate Freezer, complete the following steps: • Once the Controlled-Rate Freezer is powered up, the Thermo Scientific logo is displayed on the front screen. If this is the first time the unit is being turned on, an initial setup must be completed.
  • Page 18 If you accept the terms and conditions of using connectivity on this device you will be navigated to Wireless Setup. Select a wireless network and press the Next button. Figure 10. Terms and conditions screen If you chose to Skip this acceptance, WiFi connectivity will be disabled.
  • Page 19 Figure 15. Wireless Setup Error Message Screen Figure 18. Connect to the InstrumentConnect (via Mobile Device) Screen The Network Configuration screen appears after a successful connection is established, which displays the time and date based on the wireless network. Verify the information displayed and press Next.
  • Page 20 Figure 22. Installation Instructions (LN2 Connections) Screen The third screen provides information regarding Other Setup and Calibration. Press the Next button after reviewing. Figure 20. Connect to the InstrumentConnect (via Pass code) Screen The following screens provide installation instructions. The first screen provides information about selection of location where the unit should be placed.
  • Page 21 Figure 24. Add User Screen This screen indicates your initial setup is complete. Press the Finish button to complete initial setup or the Back button to make changes. Figure 25. Complete Setup Screen Controlled-Rate Freezer Start Up |...

  • Page 22: Operation

    Operation Home Screen Calibration: Press to view current calibration information or to perform a calibration There are 4 key elements of Home Screen on the Controlled- Rate Freezer as shown in Figure 26: Login 1. The vertical pane on the left is the navigation bar that provides access to all functions of the unit.

  • Page 23: Settings

    Figure 29. Settings Screen Figure 27. Onboard Help Screen Note: Users with Admin privileges can access all the settings, Indicators whereas other Users can access only the Printer, Display and About options. At the top left of the control panel the operating mode is indicated using below indicators: Chart No profile is running...
  • Page 24 Figure 33. Settings (Add Custom Field) Screen Figure 31. Chart color pallet Screen Alarms Chart settings are applied to both Active Run and Run Review Charts. Select Save to apply changes. When you select Alarms, the following screen is displayed: Custom Fields When you select Custom Fields, the following screen is displayed:...
  • Page 25 Figure 35. Settings (Printer) Screen Here you can adjust the Printer Time Scale and Temperature Scale from the given respective drop down menus: • Printer Time Scale: Can specify 1, 2 or 5 minutes per division on the thermal printer chart printout. •...
  • Page 26 Figure 41. Settings (Region) Screen Figure 38. Date Screen • Display Off: Allows the display to automatically be off • Time: To set the time and time format, press the Time from 9 PM to 6 AM. button. Select Save button to apply changes. •...
  • Page 27 WiFi Press Join to connect to the wireless network. A success message is displayed once the connection is established. If the connection fails, either due to an incorrect Press the WiFi button to connect to a network. Select the WiFi password or network incompatibility, a general error network from the list and press the Next button.
  • Page 28 InstrumentConnect This option displays a code that has to be entered to connect to InstrumentConnect. The following screen is displayed when you press the InstrumentConnect button in Figure 42. Figure 48. InstrumentConnect Screen Connect via Mobile Device Selecting the Connect via Mobile Device option displays a screen with instructions.

  • Page 29: Logs

    Security following screen which contains the Event Log and Run Logs buttons. Once you press the security button you will be navigated to the following screen. Figure 54. Logs Screen Event Log: All events that have occurred on the unit are Figure 52.

  • Page 30: Profiles

    provide more details. As you scroll down the list additional available data will be displayed. When the list has been sorted and filtered, press on the Export button, and the following screen will be displayed: Figure 58. Logs Export Warning Screen Run Logs When you press on the Run Logs button you will be navigated to the following screen:...
  • Page 31 The following units are used to control the individual steps of a given profile: S = Sample Probe Temperature C = Chamber Probe Temperature C/m = Degrees Centigrade per Minute The pre-set profiles are listed below: Preset_1: Commonly used for 2.0ml sample size, resulting in a 1°C rate from nucleation to -40°C and a 10°C per minute cooling rate to a -90°C end temperature.
  • Page 32 Step 3 25.0°C/m C to -50°C Step 4 10.0°C/m C to -14.0°C Step 5 1.0°C/m C to -45°C Step 6 10.0°C/m C to -90°C Step 7 Preset_5: Commonly used for skin packets, resulting in a 1°C rate from nucleation to -35°C and a 10°C per minute cooling rate to a -90°C end temperature.
  • Page 33 to the specified temperature. This step should be used when Maintains a specified Chamber temperature for the specified the starting Sample temperature is greater than the specified hold duration before proceeding to the next step. The time Sample temperature (the Sample is cooling). can be set over a range of 1 to 99 minutes, and the temperature can be set over a range of -180°C to +50°C with IMPORTANT: Step 1 only permits a Wait or Wait For as...

  • Page 34: Users

    After entering all your requirements for the specific profile press on Save to apply changes. The profile will be saved and displayed on the Profile List. Note: To edit a single line of a profile, enter View Mode, scroll to the desired profile step and Edit. Users The fifth tab on the navigation bar is the Users icon and it contains a list of both active and inactive users.

  • Page 35: Calibration

    Note: Only Admin Users can perform the Add User function. Note: There may be multiple users with admin privileges and Username should be unique so that traceability of events to there is no limit to the total number of users. the users can be maintained.
  • Page 36 Figure 76. Offset Result Screen Figure 74. Chamber Sleeve Calibrate Probe Scale Factor Calibrate Probe Offset Before starting the Scale Factor calibration insert both chamber and sample probes in LN . Pressing Calibrate Probe Scale Factor will display the following screen. Before starting the Offset calibration insert both chamber and sample probes in an ice water bath.

  • Page 37: Active Run Summary

    Active Run Summary A Profile Run can be initiated from the Profiles tab or from Note: When a profile is running the left navigation pane is not the Run Last button on the Home screen. visible. You may zoom in and out in the chart region. You may also pan tab views on the right pressing the left or Initiate a Run right arrows on the Profile Screen section...

  • Page 38: Stop A Profile Run

    Once you select a run for review you can see the details of Cool+: Energizes both the cool and cool + that specific run as shown below: solenoids. Warm: Maximum heater output. Note: Advance button will be displayed only when the first step of the profile is a wait command.
  • Page 39 Once you press on the Export button following screen will be displayed: Figure 83. Export Run File Screen Select the File Type of the exported file to be either PDF, CSV or RUN. Press on Export button. Note: PDF is the only file format that is CFR21p11 compliant. A pop-up screen as shown below will be displayed indicating the export to USB was successful.

  • Page 40: Alarms

    Alarms Chamber Thermocouple General Alarm Guidelines Failure During an active run, all alarms will display a red bell icon on top of the screen. Outside of an active run, If the chamber thermocouple cannot be detected or reads only the Power Failure alarm will display the red bell erroneous values (>75°C), an alarm will be triggered icon.
  • Page 41 • The Chamber temperature display will revert to normal Note: Profile runs cannot be initiated while this alarm is when the Chamber Thermocouple Failure alarm recovers. present. Warming mode, however, can still be initiated with a sample probe failure alarm present. Note: Neither Warming mode nor a profile run may be initiated while this alarm is present.
  • Page 42 Once the Controlled-Rate Freezer returns to Idle mode and power. The freezer will generate a Power Failure alarm the LN valves are de-energized, the alarm will automatically according to the general alarm guidelines. clear. Active Run If an active run is ongoing when the alarm occurs, the run will WARNING: Potential asphyxiation hazard.

  • Page 43: Printer Set-Up

    Printer Set-Up The built-in thermal printer (optional) has internal software 3. Install the paper roll into the paper holder. Make sure that switch settings that control how the printer interfaces with the at least 5cm of thermal paper protrudes from the paper Controlled-Rate Freezer.

  • Page 44: Specifications

    Specifications fifth and eighth shelf from the top, with the ‘Sample’ bag Temperature Uniformity placed in the top shelf. Note: Use Type ‘T’ ribbon probe thermocouple for Temperature uniformity is specified to be less than a standard Sample bag. deviation of 2°C (up to the ‘freeze’ of the first vial) across a matrix of 10 vials (1.2/2.0ml size) containing 1.0ml (±...
  • Page 45 7. 99°C/min C to -10.0°C Electrical 8. 1.0°C/min C to -2.0°C • TSCM17PA, TSCM34PA, TSCM48PA, TSCM17XA, 9. Hold 12.0 min @ -2.0°C TSCM34XA, TSCM48XA. 10. 1.0°C/min C to -20°C Nominal: 120VAC, 60Hz, 1PH, 12.0 FLA 11. END • TSCM17PV, TSCM34PV, TSCM48PV, TSCM17XV, TSCM34XV, TSCM48XV.

  • Page 46: Parts List

    Parts List Following are the list of consumable and commonly replaced Accessories parts: Table 5. Parts List The following are commonly used accessories that may be purchased separately: Part Number Description Table 6. Freezing Racks and Holders 4000566 Thermal Printer Paper, 5 rolls per box Catalog No.
  • Page 47 Table 7. Freezing Presses Catalog No. Description 4000317 Bag press for Delmed 2030-2 Bag press for 250ml bag (Fenwal 4000318 4R5461 or equivalent) Bag press for 200ml bag (Gambro DF- 4000320 200 or equivalent) Bag press for 700ml bag (Gambro DF- 4000321 700 or equivalent) Bag press for 500ml bag (Fenwal...

  • Page 48: Pc Interface Software

    PC Interface Software The CryoMed Controlled-Rate Freezer includes the PC Installation Interface companion software. The PC-based software enables the user to create and download freezer profiles. The software also allows users to remotely initiate a profile run, A Java Run Time Engine is installed with the PC interface monitor the run progress, detects and responds to error software.
  • Page 49 3. When the user inserts the USB into the USB port, they must navigate to the USB port drive location. • 64-bit location: PC INTERFACE V3-3/PCI64/PC Interface.exe. • 32-bit location: PC INTERFACE V3-3/PCI32/PC Interface.exe. Figure 99. Additional Tasks Screen 7. Allow the installation to complete. After installation is complete, it checks for the Java version 1.8 and higher in Figure 97.

  • Page 50: Login

    11. After installation is complete (Figure 101), select Close to finish. Figure 103. Launch PC Interface window Figure 101. Installation complete Screen Login 12. After completion of installation, an application is launched which will verify the COM port for connectivity with CRF The icon at right appears in the default directory unit.
  • Page 51 limited functionality. A user can login using “Anonymous” Table 10. Login Error Messages when there are no user identities created. This message appears when the user name length is not • Common Login: A user can login to the PC software between 7 to 12 characters.

  • Page 52: Setup

    Edit: The Edit screen enables the user to create and edit a Table 10. Login Error Messages freezing profile. Users can also print a profile listing. An This message appears when the user tries to login in approximate representation of the freezing profile will be Anonymous with user name entered.
  • Page 53 Information Fields Notes The Information menu contains default fields as follows: Note: Mandatory fields are marked as *. • Cryoprotectant – Enter the name of the cryoprotectant being used with the samples. The name cannot exceed 30 characters and is an optional field. •...
  • Page 54 Mode • Y-axis displays temperature in degrees Celsius (°C). Default setting for Y-axis is 5°C. • Allows the user to zoom in and out. Graph is adjusted based on the temperature selected. Press Ctrl + Mouse Left/Right button to pan around graph. Figure 113.

  • Page 55: Typical Run Procedure

    Typical Run Procedure 1. Click Open Profile. The Open window appears. 2. Select the required profile. 3. Click Open. The freezer profile is displayed. 4. Enter the Run File Name and Data Tag field. 5. The sample temperature, chamber temperature, and the profile temperature are received from the CRF unit every second.

  • Page 56: Manual Override Procedure

    number and User name will be displayed on the Right capturing data’ or ‘Stop capturing data’. No other corner of the status bar. commands can be sent from the PC. 17. The Print option allows the user to preview and print a iv.

  • Page 57: End Run

    2. If the User presses another button within 5 seconds i.e. when other button function is active, then the latest button function will be activated and previous button functionality will be stopped immediately. 3. Manual Override Buttons are available only during Run Mode.

  • Page 58: Alarms

    • “Edited” profile created date as edited date • “Printed” date and time of profile printout taken • “Data tag” entered in the profile • “Media and Sample type” values taken from the run screen • Custom fields if added any Figure 134.

  • Page 59: Power Failure Recovery

    • “Chamber temp limit” message appears when Power Failure Recovery chamber temperature is in between 55°C to 75°C or less than -185°C. If the Controlled-Rate Freezer experiences a power • “Sample temp limit” message appears when sample failure and the PC continues to operate: temperature is in between 55°C to 75°C or less than - 185°C.

  • Page 60: Display/Control Summary

    Wait For Temperature Command: Sample Temperature value must be min 1°C greater than Chamber Temperature value. Ramp Command Range: The rate of freezing must be between +0.1°C to +99.9°C and temperature values must be between -180°C to +50°C. Hold Command: Allows the user to enter a temperature range between 50°C to -180°C.
  • Page 61 The following profile steps will be available in the drop-down menu: Wait: WAIT AT X.X°C SET TEMPERATURE. Figure 142. Ramp Command This step changes Chamber temperature from its current value to specified temperature (chamber sensor trip point) at the selected rate (°C/minute). The rate can be set over a range of 0.1°C/ minute to 99.9°C/minute.
  • Page 62 Figure 144. Jump Command Automatically advances to a subsequent step or returns to a previous step in a freezing profile. The Jump function can be programmed over a range of Step 1 to END Step. Note: Chamber and Sample selection are deactivated here. Figure 146.
  • Page 63 9. Ramp rate field can take fractional values but 6. Delete All button is used to delete all steps of a profile. temperature, if set in fractions, will be rounded off to When the user clicks the Delete All button, a confirmation nearest integer.

  • Page 64: Error Messages

    • Print contains the “Author:” and Operator name. running, then the steps related to Wait, Wait for etc. will be disabled. • Print contains “Edited:” and Profile created date as Edited date. Table 11. Error Messages • Print contains “Printed:” and Date and Time of Printed as Printed.
  • Page 65 Table 11. Error Messages Table 11. Error Messages Error Message Description Error Message Description “Invalid Sample Invalid time value is This message appears when temperature value entered. Time value must This message appears when the time value is outside the entered.

  • Page 66: Review Screen

    Review Screen User Controls Review enables the user to perform the following functions: • Review: This screen enables the user to review a freezer profile. When the user opens a run file to review, the • Review a run profile properties of a freezer profile are populated automatically.
  • Page 67 The user must select the destination folder to export the file. • Page number and Thermo Scientific logo A “.csv” file contains the following information: Page 3 contains: • Company name • “Printed” date and time, Controlled-Rate Freezer review • Data tag entered by the user compare data report as header •...

  • Page 68: Options Screen

    Information Fields Options Screen Information fields on the Review screen will appear as they were created for the Run data file that has been opened. The Options enable the user to perform the following functions: following information fields will be supported. •...

  • Page 69: Default Directories

    Description 1. Click Default profile Directory folder icon. The Open window dialog box appears. 2. Select the path of the directory and click Open. 1. Plot Items are displayed as follows: 3. Click Default Run Directory. The Open window dialog box a.
  • Page 70 User name Policies • One user will not be able to change another’s password, as changing a user’s password will require his old password. • To access the application in user’s mode, a new user will have to be set up. Users cannot be imported from other Anonymous User Policies applications or previous versions of Thermo Scientific CRF software.

  • Page 71: Status Bar

    • The new fields that are added cannot have the same Table 12. Error Messages in User name as a default predefined field. Error Message • Information Field name length must be a minimum 5 characters. • Information Field name must not start with any special character or numerical value.

  • Page 72: Help

    Help The Help section assists the user in navigating through the PC Software. Figure 164. Help File About This section provides information for Thermo Fisher, the OS compatibility, and the software version of the application. Figure 165. Information 66 | PC Interface Software Controlled Rate Freezer...

  • Page 73: Maintenance

    Maintenance 3. Wash the cabinet interior using a non-abrasive cloth and WARNING: Be sure to shut down the unit using disinfectant starting at the top and working down. The shut down button (Figure 2) to disconnect the cabinet and door must be rinsed with sterile water until unit from the power source before beginning of the disinfectant has been removed.

  • Page 74: Clean The Cabinet Exterior

    Reset Heater Over temp CAUTION: Be sure all chamber components are re-installed in the proper locations to avoid compromising the chamber airflow and Thermostat temperature uniformity. CAUTION: Avoid damaging the chamber WARNING: Only qualified service personnel or opening gasket. persons experienced in servicing and maintaining laboratory equipment should perform this procedure.
  • Page 75 Table 13. Preventative Maintenance Requirements Action Each Use Daily Weekly Monthly Yearly Dry door and chamber opening gasket and heat breaks Disinfect chamber interior Clean cabinet exterior Check calibration of internal and sample probes Battery Inspect solenoid valve* *Qualified service technicians only. Controlled-Rate Freezer Maintenance |...

  • Page 76: Troubleshooting

    Troubleshooting This section is a guide to troubleshooting general operational problems. Table 14. Troubleshooting Table Symptom Possible Cause Verification Solution Power cord Verify power cord is plugged into outlet and Plug in the power cord to the unplugged to unit power inlet outlet and to the unit power inlet Front UI LED Not On...
  • Page 77 Table 14. Troubleshooting Table Symptom Possible Cause Verification Solution Printer Error Refer to printer error code table Printer Error Refer to printer error code table to diagnose and take appropriate action Check power connections at printer Connect power cable to printer Printer Power Printer Off LED Off...

  • Page 78: Connectivity Troubleshooting

    Connectivity Troubleshooting This section is a guide to troubleshooting general connectivity problems. Table 15. Connectivity Troubleshooting Table Problem Cause Solution Connectivity Dongle Unplugged Verify that the WiFi dongle is plugged into a USB port. Invalid network name Verify that the correct network name is provided. Verify that the network (SSID) is visible (being broadcasted) using a Network (SSID) is not mobile device.
  • Page 79 Table 15. Connectivity Troubleshooting Table Problem Cause Solution Verify with local IT that ports 443, 123, and 80 are open to the Internet in the facility's firewall. Use the Telnet app from a computer on the same network. Firewall ports closed *Telnet is NOT enabled by default in Windows *telnet apps.thermofisher.com 443 Connectivity Options in...

  • Page 80: Appendix A: User Role Summary

    Appendix A: User Role Summary Table 16. User Role Permissions Feature Admin User Role 1 User Role 2 • Able to start warming mode • Able to start warming mode • Able to start warming mode • Able to Run Last •...

  • Page 81: Appendix B: City Time Zone

    Appendix B: City Time Zone Time specified in the time zone indicates the difference with Table 17. City Time Zone UTC. Time Zone City Table 17. City Time Zone Sao_Tome Time Zone City Tunis (Africa | +00:00) ElAaiun (Africa | +02:00) Gaborone Freetown Harare...
  • Page 82 Table 17. City Time Zone Table 17. City Time Zone Time Zone City Time Zone City (America | -03:00) Araguaina Halifax Bahia Kralendijk Belem LaPaz Cayenne LowerPrinces Fortaleza Manaus Godthab Marigot Maceio Martinique Miquelon Moncton Montevideo Montserrat Paramaribo PortofSpain Recife PortoVelho Santarem PuertoRico...
  • Page 83 Table 17. City Time Zone Table 17. City Time Zone Time Zone City Time Zone City Nassau DawsonCreek NewYork Denver Nipigon Edmonton Panama FortNelson Pangnirtung Hermosillo Port-au-Prince Inuvik RioBranco Mazatlan ThunderBay Ojinaga Toronto Phoenix (America | -06:00) BahiaBanderas Yellowknife Belize (America | -08:00) Dawson Chicago...
  • Page 84 Table 17. City Time Zone Table 17. City Time Zone Time Zone City Time Zone City (Arctic | +01:00) Longyearbyen (Asia | +05:45) Kathmandu (Asia | +02:00) Amman (Asia | +06:00) Almaty Beirut Dhaka Damascus Omsk Famagusta Qyzylorda Gaza Thimphu Hebron Urumqi Jerusalem...
  • Page 85 Table 17. City Time Zone Table 17. City Time Zone Time Zone City Time Zone City Srednekolymsk Belgrade (Asia | +12:00) Anadyr Berlin Kamchatka Bratislava (Atlantic | -01:00) Azores Brussels CapeVerde Budapest (Atlantic | -02:00) SouthGeorgia Busingen (Atlantic | -03:00) Stanley Copenhagen (Atlantic | -04:00)
  • Page 86 Table 17. City Time Zone Table 17. City Time Zone Time Zone City Time Zone City Helsinki PagoPago Kaliningrad (Pacific | -10:00) Honolulu Kiev Johnston Mariehamn Rarotonga Riga Tahiti Sofia (Pacific | -09:30) Marquesas Tallinn (Pacific | -09:00) Gambier Uzhgorod (Pacific | -08:00) Pitcairn Vilnius...
  • Page 87 Table 17. City Time Zone Time Zone City (Pacific | +13:00) Apia Enderbury Fakaofo Tongatapu (Pacific | +14:00) Kiritimati Controlled-Rate Freezer Appendix B: City Time Zone |...

  • Page 88: Warranty

    Warranty Thermo Fisher Scientific PC and Peripheral Warranty The warranty on any of the computer components must be referred to the component manufacturer. Please contact them as needed. The Technical Services Department may be contacted for set-up and operational questions on the Controlled-Rate Freezer and PC interface, 1-888-213-1790.

  • Page 89: Thermo Fisher Scientific International Controlled-Rate Freezer Dealer Warranty

    Replacement or repair of components parts or equipment under this warranty shall not extend the warranty to either the equipment or to the component part beyond the original warranty period. The Technical Services Department must give prior approval for return of any components or equipment. At Thermo's option, all defective parts must be returned to Thermo postage paid and replacement parts are shipped FOB destination.

  • Page 90: Regulatory

    Regulatory Product Safety This product family has been tested to applicable product safety standards by Underwriters Laboratories (UL), which is a Nationally Recognized Test Laboratory (NRTL). The product bears the following mark Medical Device Registrations US FDA Class II, KSE, 510(k) exempt. 21 CFR part 11 Disclaimer The CryoMed models listed in this Operating and Maintenance manual support 21 CFR part 11 through a PDF file export and...

  • Page 91: Contact Information

    Contact Information Thermo Fisher Scientific products are backed by a global technical support team ready to support your applications. We offer cold storage accessories, including remote alarms, temperature recorders, and validation services. Visit www.thermofisher.com/cold or call: Countries Sales North America +1 866 984 3766 China +800 810 5118...

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