Emulate ORB-HM1 Manual

Hub module

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Summary of Contents for Emulate ORB-HM1

Page 1 hub module...
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Page 5 This user guide contains important information to safely and effectively operate the Orb-HM1™ instrument. Please ensure that all users thoroughly read and understand this guide before operation.
Page 6 User Guide Table of Contents Introduction Specifications Safety System Components General, Functional & Technical Information & Precautions Page 9 Page 15 Page 19 Introduction Hub Module (HM1) / Table of Contents ™...
Page 7 Installation Care Equipment & Procedure Interface & Control Panel Maintenance & Troubleshooting Page 23 Page 31 Page 35 Page 7...
Page 9 Introduction This section contains an overview of the Orb Hub Module ™ and its functions. The Orb Hub Module provides the power, gas mixture, and vacuum required for Organ-Chip cell culture. It can generate the appropriate gas mixture from an external 100% carbon dioxide supply, or from a portable carbon dioxide canister for increased flexibility.
Page 10 Orb-HM1 ™ System Components The Orb™ Hub Module provides all the necessary elements to power and run up to four Zoë™ Culture Modules at once. These elements include mixed gas, vacuum, and power. The Orb Hub Module takes 100% carbon...
Page 11 Hub Module Control Panel ™ (Front) (Rear) Provides the gas mixture, vacuum, All ports are located on the rear and power to run up to four Zoë™ Control Panel. The Orb Hub Module Culture Modules. can utilize an external CO source or a portable CO canister.
Page 12 Orb-HM1 ™ Components 1. Orb™ Hub Module 2. Main Status Indicator 3. Drip Tray Hub Module (HM1) / Introduction ™...
Page 13 Orb-HM1 ™ Control Panel 1. Power Ports 2. CO Canister Connection 3. Alarm Silence Button 4. Mixed CO 5. Vacuum Out POWER 1 & 2 6. 100% CO GAS OUT 7. Power Input & On / Off Switch POWER 3 & 4...
Page 15 Specifications This section includes specific technical information and operation requirements, such as system dimensions, temperature, and gas. Manufacturer and contact information is included here as well. Page 15 Page 15...
Page 16 Orb-HM1 ™ Specifications Manufacturer Emulate, Inc., 27 Drydock Avenue, Boston, MA 02210 Assistance For technical assistance, contact Emulate, Inc., support@emulatebio.com The Orb Hub Module is for use with the Zoë-CM1 . The Orb Hub Module is for research use only.
Page 17 General Model: HM1 Weight: 7.3 kg (16.0 lbs) Power Consumption: 105W Operating Electrical Power: 100–240VAC, 50–60Hz Requirements Gas Input Pressure: 68.9–137.9 kPa from fixed source / 20,684.3 kPa from 68-gram gas canister (10–20 psig from fixed source / 3,000 psig from 68-gram gas canister) Gas Input Composition: 100% CO Environmental Operating Temperature: 10–35ºC (50-95ºF)
Page 19 Safety This section includes precautions for handling and using the Hub Module. The information here describes how users ™ can minimize any chance of harming themselves or the Orb Hub Module during use. Additionally, regulatory compliance information is contained in this section. Page 19 Page 19...
Page 20 Safety The Instructions Symbol The product is marked with this warning symbol where it is necessary for the user to refer to the instructions in the user guide. Regulatory Compliance and Testing This product has been tested to the requirements of: 61010-1 (IEC, EN, CSA) Safety Requirements for Electrical Equipment for Laboratory Use EMC Directive 2014 / 30 / EU, LVD Directive 2014 / 35 / EU EN 61326-1 Electro-Magnetic Compliance (EMC)
Page 21 Never attempt to disassemble or repair the Hub Module. Never attempt to replace any fuses. CAUTION Service and maintenance should only be completed by Emulate-certified personnel. CAUTION Remove the Power Cord from the Hub Module and / or from the wall power outlet to completely disconnect the module from AC power in the event of an emergency.
Page 23 The CO canister is available from Emulate separately, and requires periodic replacement based on usage. The installation process is described in seven simple steps. This operation should only be performed by Emulate-certified personnel.
Page 24 Equipment Provided by Emulate Vacuum Mixed Gas Hub Module Input Line ™ Connector Line Connector Line (Incl. Filter) (Incl. Filter) Hub Module (HM1) / Installation ™...
Page 25 Power Cables (4) Vacuum & Gas Canister Power Cord Hubs (for Zoë Culture Modules) (Not included) ™ Page 25...
Page 26 POWER POWER 1&2 1&2 GAS OUT GAS OUT POWER POWER 3&4 3&4 VAC OUT VAC OUT GAS IN GAS IN Drip Tray is flush with Orb exterior Connect CO Connect CO Place Check Line Canister Check that the Orb Drip Tray is Connect 100% CO from external Connect CO...
Page 27 TIP: The Orb™ Hub Module can be connected to both sources simultaneously. If pressure from external CO source drops below 10 psig, it will automatically switch to canister as CO source. TIP: To remove the CO canister, slowly unscrew the canister from the Orb Hub Module.
Page 28 POWER 1&2 GAS OUT POWER 3&4 POWER 3&4 VAC OUT GAS IN POWER 1&2 GAS OUT POWER 3&4 VAC OUT GAS IN Connect Zoë™ Connect Hubs Power Verify Culture Modules Connect Vacuum and Gas Connect Zoë Power Cables to the Connect the Power Cord to the Verify that the Main Status Indicator ™...
Page 29 POWER 1&2 GAS OUT POWER 3&4 VAC OUT GAS IN GAS OUT VAC OUT GAS IN Page 29...
Page 31 This section describes how to interact with the Orb ™ Module. The Main Status Indicator reflects the real-time status of the Orb Hub Module. There are additional indicators on the rear Control Panel. Page 31 Page 31...
Page 32 Interface & Control Panel Main Status & Control Panel Indicators The Main Status Indicator will display one of the following three statuses: pulsing blue, solid red, or pulsing red with audible alarm. ™ Each status represents the current state of the Orb Hub Module.
Page 33 Alarm Silence Button GAS OUT VAC OUT GAS IN Indicators Pulsing Red Pulsing Blue Solid Red Control Panel & Alarm Solid red indicates the CO canister Pulsing red with alarm indicates an The Control Panel Indicators identify ™ Pulsing blue indicates the Orb is low, and needs replacement.
Page 35 Caring for Zoë Care Rorem nulparum, sinihilibus aut quatis nos ullabor ectiae exera This section details steps to ensure the Orb Hub Module ™ volupta aspera cuptur aut landunt. is functioning as intended. Care includes periodic cleaning, Cil illes que es nobisit haris id quundit omniscienis ma et et et emptying the Drip Tray, and checking indicators.
Page 36 Care Cleaning & Maintenance ™ The Orb Hub Module does not require significant maintenance. The outer surface should be cleaned periodically with 70% ethanol. The Drip Tray collects any condensation that may accumulate as a result of regular Orb Hub Module use — this is normal. The Drip Tray should be checked every week and emptied as needed.
Page 37 GAS OUT VAC OUT GAS IN Indicators Clean Drip Tray Indicators Record Every week check the Drip Tray. Check the Control Panel Indicators Keep a record of all maintenance ™ To clean the Orb Hub Module, Empty as needed and clean with daily for any errors.
Page 38 Check the power rating, voltage, and frequency the specified electrical requirements of the wall outlet with the input range specified in this guide and on the Orb label The fuse in the system is blown Contact Emulate for troubleshooting Hub Module (HM1) / Care ™...
Page 39 The power connector is not connected or is Connect the Power Cord securely to both the Zoë connected incompletely culture module and Orb Hub Module The Power Cord is damaged Replace Power Cord; contact Emulate for ™ ™ Zoë Culture Module is connected to the Orb...
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