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Summary of Contents for REPLIGEN TangenX SIUS PD
- Page 1 TangenX™ SIUS™ PD Filter Plate and 2-Bolt Clamp Assembly USER GUIDE Page 1 of 12 Identification IF.PUG.019 Revision Approved 20-DEC-2018...
- Page 2 The information contained in this document is subject to change without notice. Repligen Corporation makes no warranty of any kind with regard to this material, including, but not limited to, the implied warranties of merchantability and fitness for a particular purpose.
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Page 3: Table Of Contents
10. Used TangenX™ SIUS™ PD Cassette Disposal ................ 10 11. Unused TangenX™ SIUS™ PD Cassette Storage ..............10 12. Membrane Operating Characteristics ................... 10 13. Chemical Restrictions ......................11 14. Repligen TangenX™ Standard Warranty ................12 List of Tables Table 9.1 Recommended cleaning solutions ..................9 Table 12.1... -
Page 4: Diagram
TangenX SIUS PD Filter Plate & 2-Bolt Clamp Assembly User Guide 1. Diagram Filter Area: 0.01 m² to 0.06 m² (TFPLS-LVFL) Clamp Weight: 13 lbs 0.1 m² to 0.5 m² (TFPLS-SA08) Max Cross Flow: 0.48 LPM (TFPLS-LVFL) Clamp Weight (loaded): 13 lbs to 20 lbs 9 LPM (TFPLS-SA08) Filter Plate Certificate: Provided with each FPI kit... -
Page 5: Product Contents
- TFPLS-SA08 and TFPLS-LVFL is compatible with all TangenX™ SIUS™ single-use cassettes and TangenX™ PRO reusable cassettes. - Filter Plate Inserts are designed for single-use. Since Repligen does not recommend re-use, it is the responsibility of the end user to define a suitable cleaning protocol. -
Page 6: Tools Required
TangenX SIUS PD Filter Plate & 2-Bolt Clamp Assembly User Guide • PUMP When using TangenX™ cassettes, select a pump with adequate capacity. Crossflow rate ranges (see Table 12.1) are feed channel type and process fluid dependent. 4. Tools Required •... -
Page 7: Tangenx™ Sius™ Pd Cassette Installation
TangenX SIUS PD Filter Plate & 2-Bolt Clamp Assembly User Guide CAUTION: Please be careful when tightening any tri-clamp connectors to the Filter Plate. It is possible to crack the Filter Plate sanitary connection by squeezing it too tightly. Hand tightening should be sufficient to any gaskets. -
Page 8: Tangenx™ Sius™ Pd Cassette Equilibration
TangenX™ SIUS™ PD cassettes are intended for single use, therefore post-use cleaning and re-use is not recommended nor supported by Repligen. Similarly, the Filter Plate Insert Kit is also designed for single use, and like the TangenX™ SIUS™ PD cassette, post-use cleaning is not supported by Repligen. -
Page 9: Table 9.1 Recommended Cleaning Solutions
TangenX SIUS PD Filter Plate & 2-Bolt Clamp Assembly User Guide 2. Remove from clamp the following: Isolation Plate, all gaskets, all cassettes and Filter Plate Insert. 3. Wipe down any spillage from clamp components. 4. Store clamp top plate on clamp base (or other location) along with nuts, washers and spacers. FOR TRADITIONAL SANITARY HARDWARE SYSTEM: To clean the TFF system following use, recirculate 0.5M sodium hydroxide through the system with all valves open. -
Page 10: Used Tangenx™ Sius™ Pd Cassette Disposal
TangenX SIUS PD Filter Plate & 2-Bolt Clamp Assembly User Guide 10. Used TangenX™ SIUS™ PD Cassette Disposal TangenX™ SIUS™ PD cassettes are removed from the clamp by reversing the cassette installation procedure. If the cassettes are difficult to separate and remove from the stack, a thin plastic spatula can be slid under the edge of the cassette to break the seal. -
Page 11: Chemical Restrictions
TangenX SIUS PD Filter Plate & 2-Bolt Clamp Assembly User Guide Table 12.3 Air integrity test specifications Air Diffusion Rates Ultrafiltration ≤ 323 sccm/m2 @ 15 psi 1kD thru 5kD (1 bar) Ultrafiltration ≤ 323 sccm/m2 @ 7.3 psi 10kD thru 300kD (0.5 bar) Microfiltration ≤... -
Page 12: Repligen Tangenx™ Standard Warranty
In the event of a breach of the foregoing warranty, Repligen’s sole obligation shall be to repair or replace, at its option, the applicable product or part thereof, provided the customer notifies Repligen promptly of any such breach.
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