Page 1: Table Of Contents
Contents Introduction ........2 Membrane Type ......2 Pump Capacity ......2 Water Quality ......2 Installation ........2 Pellicon 3 88 cm and 0.11 m ® Cassette Holder Installation ... 2 Pellicon 3 0.57 or 1.14 m Cassette ® Installation and User Benchtop Holder Installation ..
Page 2: Introduction
Pellicon 3 Cassettes Installation and User Guide ® Introduction Installation This guide provides installation and Pellicon 3 88 cm and 0.11 m Cassette Holder Installation ® maintenance procedures for Pellicon ® NOTE cassettes. It is not intended to provide Pellicon 3 88 cm and 0.11 m Cassettes must be installed in a Pellicon...
Page 3: Benchtop Holder Installation
Pellicon 3 Cassettes Installation and User Guide ® Pellicon 3 0.57 or 1.14 m Cassette Benchtop Holder Set the torque wrench at 180 to 200 ® in. lb. (20.3 to 22.6 Nm) by holding Installation the spring loaded lock collar down XX42P0060 Pellicon Cassette Acrylic Filter Holder ®...
Page 4: Manual Process-Scale Holder Installation
Pellicon 3 Cassettes Installation and User Guide ® 11. Using the torque wrench and 15/16 in. deep hex socket, turn each nut 1/8 turn in the sequence shown here. When the hex nut washer washer wrench clicks, this indicates that the set stainless steel force has been reached.
Page 5: Hydraulic Process Scale Holder Installation
Pellicon 3 Cassettes Installation and User Guide ® Hydraulic Process Scale Slide the Pellicon 3 cassette up against the manifold adapter plate. The dark ® grey center with light grey perimeter of the manifold adapter plate should be up Holder Installation against the Pellicon 3 cassette.
Page 6 Pellicon 3 Cassettes Installation and User Guide ® Holder Pressurization and On the first holder level (if there the System Pressure Manual Dump are more than one), remove the Valve, MV-1 on the left side of the Operation TC clamps and inserts holding the Hydraulic Power Unit.
Page 7: Maintenance
Pellicon 3 Cassettes Installation and User Guide ® Maintenance Flushing and Cleaning Pellicon 3 Cassettes must be operated while under compression from the holder ® assembly to ensure that the cassettes will seal properly. The compression is supplied Flushing and cleaning are required for by applying torque to the nuts on the threaded tie-rods of the holder assembly.
Page 8: Flushing
Pellicon 3 Cassettes Installation and User Guide ® Flushing depyrogenation and residual flush out Once the pump has slowly ramped from the system. To select a cleaning up to the set point, partially close The flushing step removes residuals method, identify your application or the retentate valve (V4) to achieve from the cassette and the system suspected foulant from the Cleaning...
Page 9: Sanitization
Pellicon 3 Cassettes Installation and User Guide ® Primary Cleaning Agents and Conditions for Organics, Biofilms, water into the feed port of the Pellicon holder. The recommended Biopolymer, Proteins and Polyphenolic ® feed flow rate is 4 to 6 L/min/m². Cleaning Temperature Time...
Page 10: Depyrogenation
Pellicon 3 Cassettes Installation and User Guide ® Integrity Testing * Typical Peracetic acid-containing cold sanitant contain 20-24% Hydrogen Peroxide, 4.6% Peracetic acid, and 8-10% Acetic acid. Pellicon 3 filter integrity should be ® ** Use milder conditions if effectiveness of agent is still observed. Better membrane tested on a cleaned and thoroughly life is expected with lower concentration of caustic and/or at 20-25 °C for regenerated flushed system.
Page 11: Measurement Of Normalized Water Permeability
Pellicon 3 Cassettes Installation and User Guide ® Measurement of Slowly raise the air pressure to the screens is 4 to 6 L/min/m². (The recommended test value and wait same conditions MUST be used each Normalized Water 5 minutes to purge residual water time NWP is measured in order to in the permeate line.
Page 12: Storage
Pellicon 3 Cassettes Installation and User Guide ® Storage importance is stable process flux and no carry over. If the NWP decreases significantly from run-to-run, cleaning procedures may be Storage solution must be introduced into inadequate. Alternative cleaning agents and procedures should be investigated. the system through the cassettes and Contact a Technical Service Representative for assistance.
Page 13 Pellicon 3 Cassettes Installation and User Guide ® NOTE to prevent possible microbial growth or If the system is complex and has other associated manifolds, ensure that all contamination. wetted surfaces in the manifolds are exposed to the solution. All valves that have Ultracel membranes can be stored in ®...
Page 14: Troubleshooting
Pellicon 3 Cassettes Installation and User Guide ® Troubleshooting Symptom Possible Cause Remedy Symptom Possible Cause Remedy Integrity test Areas of membrane Repeat Flushing High NWP Damage to membrane Integrity test cassette failure or low incompletely wetted Procedure. Flush with or cassette retention water, retest...
Page 15: Warranty
Pellicon 3 Cassettes Installation and User Guide ® Warranty Symptom Possible Cause Remedy Bubbling at Dirt, debris or loose See remedy under The applicable warranty for the products external holder, or chemical Leak Between Filters listed in this publication may be found surface of incompatibility above.
Page 16 We provide information and advice to our customers on application technologies and regulatory matters to the best of our knowledge and ability, but without obligation or liability. Existing laws and regulations are to be observed in all cases by our customers. This also applies in respect to any rights of third parties. Our information and advice do not relieve our customers of their own responsibility for checking the suitability of our products for the envisaged purpose.