Figure 2. Representative examples of the appearance of healthy vs. suspicious oral tissue under both incandescent light and
VELscope examination.
Normal Floor of the Mouth
Sometimes the area around the sub-lingual gland can be well vascularized, and can lead to a variable
degree of loss of fluorescence.
Normal Variation - Oropharynx with Numerous Lymphoid Aggregates
Sometimes the oropharynx can host varying numbers of lymphoid aggregates, which, due to tissue structure,
display a pronounced loss of fluorescence.
Irritation and Inflammation
The buccal mucosa is a common site for irritation and consequent inflammation; inflammation always shows a distinct loss of
fluorescence because of increased blood content.
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