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Curr Pediatr Res 2017; 21 (1): 148-157
Assessment and treatment of pain in pediatric patients.
Halefom Kahsay
Department of Pharmacy, Collage of Health Science, Adigrat University, Adigrat, Ethiopia.
Pediatric patients experience pain which is more difficult to assess and treat relatively to
adults. Evidence demonstrates that controlling pain in the pediatrics age period is beneficial,
improving physiologic, behavioral, and hormonal outcomes. Multiple validated scoring
systems exist to assess pain in pediatrics; however, there is no standardized or universal
approach for pain management. Healthcare facilities should establish pediatrics pain control
program. This review summaries a collection of pain assessment tools and management
practices in different facilities. This systematic approach should decrease pediatric pain and
poor outcomes as well as improve provider and parent satisfaction.
Keywords: Pain, Pain assessment, Pain management, Pediatric patients.
Introduction
According to the International Association for the Study of
Pain (IASP) Pain is "an un-pleasant sensory and emotional
experience associated with actual and potential tissue
damage". Pain has also been defined as "existing whenever
they say it does rather than whatever the experiencing
person says" [1-4]. It is one of the most dreading and
devastating symptom commonly propagated in peoples
with advanced chronic conditions including cancer patents.
Pediatric patients are the most under treated and present to
hospital for pain compared to adults; because of the wrong
belief that they neither suffer pain nor they remember
painful experiences [5]. The quality of life experienced
by the patient can greatly reduce, regardless of their basic
diagnosis. Thus, if pain will be poorly managed, it can
reflect the influence on family and careers causing different
which may leads to increased rates of hospital admission
[5,6]. Uncontrolled pain has also direct impact on health
outcomes and more than a few effects on all areas of life.
The emotional, cognitive, and behavioral components of
pediatric patient are also important to assess pain and to
simplify the management practices [7,8].
A long-term negative effect of untreated pain on pain
sensitivity,
immune
attitudes, and health care behavior are supported with
numerous evidences. Health care professionals' who care
for children are mainly responsible for abolishing or
assuaging pain and suffering when possible [5,7,9]. The
practice of pediatric pain treatment protocol has made
great progress in the last decade with the development
148
functioning,
neurophysiology,
Abstract
and validation of pain valuation tools specific to pediatric
patients. Almost all the major children hospitals now
have dedicated pain services to provide evaluation and
immediate treatment of pain in any child [10,11].
In pediatric age, it is more difficult to assess and treat pain
effectively relatively to adults. The lack of ability to notice
pain, immaturity of remembering painful experiences
and other reasons are the reflection of persistence of
myths related to the infant's ability to perceive pain [12].
However, the treatment of pain in childhood is like the adult
management practice which includes pharmacological and
non-pharmacological interventions. On the other hand,
it critically depends on an in-depth understand of the
developmental and environmental factors that influence
nociceptive processing, pain perception and the response
to treatment during maturation from infancy to adolescence
[13,14].
The practice of assessing pain and its management in
pediatric patients can show a discrepancy based on the
different countries and their respective health institutions.
So, this review focused on the contemporary practice
and new advances in pediatric pain assessment and its
management.
Classification of Pain
Many classification systems are used to describe the
different types of pain. The most common classification
schemes refer to pain as acute or chronic; malignant or
nonmalignant; and nociceptive or neuropathic [15]. Most
studies are agreed with the following classification of pain
(Table 1).
ISSN 0971-9032
www.currentpediatrics.com
Accepted January 30, 2017
Curr Pediatr Res 2017 Volume 21 Issue 1

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  • Page 1 Curr Pediatr Res 2017; 21 (1): 148-157 ISSN 0971-9032 www.currentpediatrics.com Assessment and treatment of pain in pediatric patients. Halefom Kahsay Department of Pharmacy, Collage of Health Science, Adigrat University, Adigrat, Ethiopia. Abstract Pediatric patients experience pain which is more difficult to assess and treat relatively to adults.
  • Page 2 Assessment and treatment of pain in pediatric patients. Table 1. The general classification of pain in pediatrics [3,4,8,15-20] Category Sub-classification Description This type of pain arises as the tissue injury activates specific pain receptors named nociceptors, which are sensitive to noxious stimuli. These receptors’...
  • Page 3 Kahsay children and across all settings. Individual needs of the after observing the infant for 1 min. Among two observers children lead to assess and re-evaluate of pain consistently a reliability of FLACC was established in a total of 30 as a mandatory in every situation.
  • Page 4 Assessment and treatment of pain in pediatric patients. Assessment of pain in older children: Management of Pain in Pediatrics The management of pain in pediatrics is still Self-report: The single most reliable indicator of misunderstood. Explicitly, neonates and infants are not the existence and intensity of pain and any resultant distress is the patient’s self -report.
  • Page 5 Kahsay demonstrated that skin-to-skin contact principally surgical visit for patients and their families is important to Kangaroo care plays its own role in reducing and caring develop their perception towards pain management [40]. A study by Lm Zhu et al. in Canadian pediatric teaching their children as the care giver and the baby have a direct hospitals indicated that out of the 55 (83.3%) children physical contact [4,30].
  • Page 6 Assessment and treatment of pain in pediatric patients. Figure 3. The WHO analgesic ladder [15,24,45] Table 4. Dosage guidelines for the common non-opioids used in the management of pain in pediatrics [12,48] Usual Pediatric Drug Oral peak time Usual Adult dosage Comments dosage 10–15 mg/kg every Lacks the peripheral anti-...
  • Page 7 Kahsay tablet and intravenous formulations. It is used to close Codeine: It is a prodrug which activated to morphine by patent ductus arteriosus (PDA) and as pain reliever in the enzyme cytochrome CYP2D6. However, the activity of perioperative in neonates and children weighing greater this enzyme is highly variable and shows inter-individual than 7 kg.
  • Page 8 Assessment and treatment of pain in pediatric patients. Table 7. Opioids commonly used in pediatric pain management [12,50,51] Usual Recommended Starting Dose Drugs Comments Oral Parenteral Used as a standard of Morphine 0.3 mg/kg every 3–4 h 0.1 mg/kg every 3–4 h comparison for all opioid drugs Codeine is a pro-drug and...
  • Page 9 Kahsay 4. Gerik SM. Pain management in children: Developmental assessment during blood collection from sedated and considerations and mind-body therapies. South Med J mechanically ventilated children. Rev Bras Ter Intensiva 2005; 98: 295-301. 2016; 28: 49-54. 5. General Palliative Care Guidelines for the Management 23.
  • Page 10 Assessment and treatment of pain in pediatric patients. 46. Yung A, Thung A, Tobias JD. Acetaminophen for 39. Management of pain in children: Pain guidelines 2006. analgesia following pyloromyotomy: Does the route of 40. Glowacki Effective pain management administration make a difference? J Pain Res 2016; 9: improvements in patients’...