1. Manuals
  2. Brands
  3. MSD Manuals
  4. Scales
  5. SECTOR Image 2400
  6. Instrument manual

MSD SECTOR Image 2400 Instrument Manual

Hide thumbs
Table of Contents

Advertisement

Quick Links

Download this manual
INSTRUMENT MANUAL
SECTOR Imager
®
Models 2400 & 6000
ww w. mes os c a le.com
®

Advertisement

Table of Contents
loading
Need help?

Need help?

Do you have a question about the SECTOR Image 2400 and is the answer not in the manual?

Questions and answers

Summary of Contents for MSD SECTOR Image 2400

  • Page 1 INSTRUMENT MANUAL SECTOR Imager ® Models 2400 & 6000 ww w. mes os c a le.com ®...
  • Page 2 No part of this Manual may be duplicated, reproduced, stored in a retrieval system, translated, transcribed, or transmitted in any form or by any means without the express prior written permission of MSD. This Manual shall be returned to MSD within two (2) business days following any request by MSD.

  • Page 3: Table Of Contents

    Power Switch and Input/Output (I/O) Panel ..................22 3.5.10 Halt Button ............................ 23 Microsoft Windows-Compatible Workstations ....................24 MSD DISCOVERY WORKBENCH Software ..................... 25 Operational Modes ............................25 Image Readout ............................. 25 3.10 SECTOR Imager Demonstration Test Plate ..................... 26 3.11...
  • Page 4 Figure 3:11 The SECTOR 2400/2400A reads 96-well plates in 24 sectors ................26 Figure 3:12 SECTOR Imager 6000 Demonstration Test Plate ..................... 26 Figure 3:13 Loading a SECTOR Imager demonstration plate ..................... 27 Figure 5:1 Instrument Status window..........................31 Figure 5:2 MSD DISCOVERY WORKBENCH desktop icon ....................32...
  • Page 5 Figure 5:3 SECTOR Imager icon ............................32 Figure 5:4: MSD DISCOVERY WORKBENCH splash screen ....................33 Figure 5:5 SECTOR Imager Window: Setup, Plate Summary, and Operations areas ............34 Figure 5:6 Stacker cover over the output port with empty single plate adapter in the input port ........... 34 Figure 5:7 SECTOR Imager demonstration plate in the single plate adaptor ...............
  • Page 6 Introduction...

  • Page 7: Introduction

    MSD develops, manufactures, and markets detection instrument systems as well as a line of assay kits for use with these instruments, a proprietary line of reagents, and custom microplate printing and assay development services. MSD MULTI-ARRAY microplates are available in 96-, 384-, and 1536-well formats with standard or high-binding surfaces.

  • Page 8: Formatting Information

    Tips  Symbol Tips provide extra information or details that help users perform functions more efficiently. Notes Notes provide supplemental information on the proper use of the SECTOR Imager and its software. Warnings and Caution Symbols WARNING General warnings advise operators of potential hazards and highlight the procedures or information necessary to avoid personal injury during use of the SECTOR Imager.
  • Page 9 Important Information...

  • Page 10: Important Information

    Important Information General Operation The SECTOR Imagers are designed to run 24 hours a day. Once initialized, the SECTOR Imager enters standby mode when plates are not running. Standby maintains the CCD detector temperature. The SECTOR Imager requires no additional initialization when left in standby mode.

  • Page 11: Electrical

    Imager was designed and tested in compliance with appropriate electrical safety standards. WARNING: The SECTOR Imager contains AC voltages. DO NOT ATTEMPT TO SERVICE OR REPAIR THE SECTOR IMAGER. Please contact MSD Instrument Service for all service and repair, including electrical problems.

  • Page 12: Chemical And Biological

    Although the SECTOR Imager is shielded and grounded, laboratory personnel should never remove any instrument covers that would expose electrical circuits. Only authorized MSD Service personnel should perform repairs to the interior of the SECTOR Imager. strongly NOTE: We recommend that users of laboratory instruments (such as the SECTOR Imager) follow the Clinical and Laboratory Standards Institute (CLSI) document entitled GP17-A2, Clinical Laboratory Safety;...

  • Page 13: Mechanical

    Changes or modifications not expressly approved by MSD may void the warranty. The operator shall use any special accessories provided with the equipment such as the power supply or shielded cables that are necessary for compliance with FCC standards.

  • Page 14: Software Compatibility

    The SECTOR Imager may have been used to analyze infectious materials or in an environment where infectious materials were handled. For the protection of future users and service personnel, please follow site safety procedures and the directions of the site safety officer to disinfect the SECTOR Imager before shipping or service. Please contact MSD Instrument Service for details.
  • Page 15 System Description...

  • Page 16: System Description

    70 seconds per plate. The SECTOR Imager 2400/2400A reads plates at a rate of approximately 3 ½ minutes per plate. Using MSD DISCOVERY WORKBENCH software, all models provide the capability to interact with a third party external robotic controller.

  • Page 17: System Components

    3:1): • SECTOR Imager instrument • Microsoft Windows-compatible workstation • MSD DISCOVERY WORKBENCH software • SECTOR Imager demonstration plate • Cables (SECTOR Imager 6000 [model 1200] and SECTOR Imager 2400/2400A [models 1250/1251]): power, RS-232, USB, and camera serial cable •...

  • Page 18: Ccd Camera And Telecentric Lens

     Additional stack tubes, single plate adaptors, and stacker cover plates may be purchased from MSD. Figure 3:2 SECTOR 6000 Imager components NOTE: The SECTOR Imager 2400/2400A employs a different CCD camera and a different custom lens optimized to read MULTI-ARRAY plates in 24 sectors (not shown).

  • Page 19: Motion Control System

    MSD barcode label that uniquely identifies the plate and allows the SECTOR Imager to detect the type of plate being run. If desired, the user may apply a custom barcode label either on the same side of the plate as the MSD barcode or on one of the short sides of the plate.

  • Page 20: Single Plate Adaptor

    Figure 3:3 Input (right) stacker interface plate Figure 3:4 Fully loaded standard and high capacity stack tubes Single Plate Adaptor 3.5.6 The SECTOR Imager reads single plates placed manually into the single plate adaptor. When inserting the single plate adaptor into the stacker, ensure that the single plate adaptor is fully seated on the stacker interface plate.

  • Page 21: Stacker Cover Plate

    Stacker Cover Plate 3.5.7 The stacker cover plate (Figure 3:5 left side of image) is used to cover the output (left) stacker interface when the machine is set to return single plates to the input side. Both stacker interface plates should be covered when the machine is not in use. The SECTOR Imager 2400A comes preconfigured to return plates to the input side.

  • Page 22: Power Switch And Input/Output (I/O) Panel

    Figure 3:6 SECTOR Imager status LEDs Power Switch and Input/Output (I/O) Panel 3.5.9 The I/O panel of the SECTOR Imager, located on the rear right side of the SECTOR Imager, includes the instrument’s power switch, power entry module, and connectors for USB, RS-232, camera serial communications, and robotic halt activation cables (Figure 3:7).

  • Page 23: Halt Button

    The halt switch should never be obstructed or restricted from access. The halt function can also be accessed through the rear I/O panel to enable external safety devices to halt the motion of the SECTOR Imager. Please contact MSD Scientific and Technical Support for more information on this feature.

  • Page 24: Microsoft Windows-Compatible Workstations

    Figure 3:8 SECTOR Imager halt button Microsoft Windows-Compatible Workstations Computer workstations are configured by MSD for use with the SECTOR Imager and come preloaded with MSD DISCOVERY WORKBENCH application software (3.7 MSD DISCOVERY WORKBENCH Software). The workstation includes a personal computer, display, keyboard, and mouse.

  • Page 25: Msd Discovery Workbench Software

    MSD DISCOVERY WORKBENCH Software DISCOVERY WORKBENCH is a Windows application that supports the operation of SECTOR Imagers, stores both current and historical plate data, and analyzes and presents results. The application has several components: instrument modules, a secure database (the Plate Data History), kit layouts, data integrity features, and data analysis functions. Please refer to the DISCOVERY WORKBENCH User Guide for additional information.

  • Page 26: 3.10 Sector Imager Demonstration Test Plate

    It should be used to verify the function of the SECTOR Imager. The demonstration plate consists of an electronic circuit board housed in a plastic carrier in the shape of a standard plate. The circuit board for the SECTOR Imager 6000 has six separate sectors, simulating the structure of MSD MULTI-ARRAY plates (Figure 3:12) as read by the SECTOR Imager 6000.

  • Page 27: 3.11 Uninterruptible Power Supply

    To use, place the demonstration plate in the single plate adaptor with the chamfered corners of the plate facing into the instrument (Figure 3:13). This orientation ensures that the bar code reader can automatically read the bar code label. See Section 5 Quick Start for more details.
  • Page 28 Installation...

  • Page 29: Installation

    Installation A qualified MSD service engineer must install and configure the SECTOR Imager before use. Installation includes setup, connection of the instrument to its computer system, and verification that the instrument is functioning properly. Only the computer provided with the instrument and configured by an MSD service engineer should be used to operate the SECTOR Imager.
  • Page 30 Quick Start...

  • Page 31: Quick Start

    The SECTOR Imager has a cooled CCD camera that needs to be brought to operating temperature before plates are read. To initiate the cooling process, the SECTOR Imager must be turned on, the MSD DISCOVERY WORKBENCH software must be started, and the SECTOR Imager Tools must be running (see steps 1–4 below).

  • Page 32: Figure 5:2 Msd Discovery Workbench Desktop Icon

    Log on to the Windows operating system. To do this, enter Administrator as the user login name and MsdAdmin as the password. (This is the default login shipped with the system; you may change this login/password or add additional Windows user accounts.) If DISCOVERY WORKBENCH does not start automatically, double-click the MSD DISCOVERY WORKBENCH icon on the Windows desktop (Figure 5:2).

  • Page 33: Setup

    Figure 5:4: MSD DISCOVERY WORKBENCH splash screen Setup On the left side of the SECTOR Imager window, users can view and edit the Setup selections for the demonstration plate read (Figure 5:5). Select Read from Bar Code from the Plate Type menu.

  • Page 34: Figure 5:5 Sector Imager Window: Setup, Plate Summary, And Operations Areas

    Figure 5:5 SECTOR Imager Window: Setup, Plate Summary, and Operations areas Place the single plate adaptor on the input (right) stacker interface plate (Figure 5:6). Figure 5:6 Stacker cover over the output port with empty single plate adapter in the input port Load the SECTOR Imager demonstration plate into the single plate adaptor (Figure 5:7).

  • Page 35: Run

    Figure 5:7 SECTOR Imager demonstration plate in the single plate adaptor NOTE: If the SECTOR Imager is unable to read the barcode on the demonstration plate (or if no barcode label is present), the plate will be skipped and ejected from the instrument. Please contact MSD Scientific and Technical Support assistance.

  • Page 36: Figure 5:8 Sector Imager Window, Run Options Dialog Box

    Figure 5:8 SECTOR Imager window, Run Options dialog box Quick Start...

  • Page 37: Results

    Results The software provides several options for viewing results. Select View  Layer Views from the menu or select a layer from the Layer menu on the toolbar. Refer to the DISCOVERY WORKBENCH User Guide for details on data viewing options. If you observe the data as it is acquired in Color Map view, bright wells should display numbers above 2000 and dark wells should display numbers below 200.
  • Page 38 Using the SECTOR Imager...

  • Page 39: Using The Sector Imager

    DISCOVERY WORKBENCH User Guide for detailed instructions on running MULTI-ARRAY plates on the SECTOR Imager system. NOTE: This section assumes that a qualified MSD service engineer has installed and configured the instrument, and that the user has run a demonstration plate as described in the previous section.

  • Page 40: Figure 6:1 Loading Multi-Array Plates Into Stack Tube

    Orient the stack tube so that the chamfers of the plates are toward the back of the instrument and the bar code labels are to the left. NOTE: A label on the inside of the stack tube reminds users of the correct orientation for loading plates. The stack tube itself will only fit on the interface plate in one orientation.

  • Page 41: Unloading The Stack Tube

    All SECTOR Imagers can be integrated with a robotics system for loading and unloading plates using the Remote Instrument Mode, which allows the instrument to be used as a component through its remote interface. A Remote Instrument Manual that provides descriptions of the commands recognized by the MSD software is available upon request. Contact Scientific and Technical Support for more information on robotics integration.
  • Page 42 Maintenance...

  • Page 43: Maintenance

    Maintenance This chapter contains basic maintenance instructions for the SECTOR Imager and some components. A qualified MSD service engineer should perform all other maintenance procedures not described in this section. WARNING: Opening the instrument to perform maintenance incurs risk of mechanical, electrical, and laser harm.

  • Page 44: Instrument Decontamination

    Contact MSD Scientific and Technical Support for a detailed protocol for instrument decontamination. NOTE: The SECTOR Imager must be decontaminated prior to shipping the instrument back to MSD. Contact MSD Scientific and Technical Support prior to shipping for instructions and requirements.
  • Page 45 Appendix...

  • Page 46: Appendix

    Disable the antivirus program temporarily to see if that is the issue. There are several been installed on the instrument methods: computer. Exclude the file: C:\Program Files\MSD Discovery Workbench\lib\prefs.properties from scanning. Disable real-time scanning. Uninstall the antivirus program and use a different one.
  • Page 47 Perform the following steps: file corrupted. Completely close DISCOVERY WORKBENCH. Go to C:\Program Files\MSD DISCOVERY WORKBENCH\Data and look for a file DISCOVERY WORKBENCH v3 only called SECTORHTSInventory.ini (SECTOR Imager 6000) or SECTORHTS24Inventory.ini (SECTOR Imager 2400/2400A). If the file does not exist look for SECTORHTSInventory.ini.bak (SECTOR Imager 6000) or SECTORHTS24Inventory.ini.bak (SECTOR Imager 2400/2400A).Once...
  • Page 48 Error 8906 Invalid Plate Type The software failed to recognize the Check to see if Bar Code Update for MSD DISCOVERY WORKBENCH has been installed at barcode on the MSD plate. the following location: START Menu  Settings  Control Panel  Add or Remove Programs.
  • Page 49 Overwrite events older than <xx> days (enter the maximum number of days for keeping older events). NOTE: Setting the system log to overwrite will result in a loss of data. MSD recommends archiving the log periodically.

  • Page 50: Specifications

    Specifications SECTOR Imager 8.2.1 NOTE: All performance information including standard signal levels, detection limits, dynamic range, and instrument noise is based on 150 µL read volumes in 96-well MULTI-ARRAY plates using standard plate read parameters. Unless noted, specifications apply to all models of the SECTOR Imager 2400/2400A and the SECTOR Imager 6000. Scientific Performance 8.2.2 Table 8:2 Scientific performance...

  • Page 51: Sector Imager Physical Dimensions

    Fuses Electrical fuses are only accessible by MSD service engineers and are not user-serviceable. The information below is provided for reference. Main Fuses F1 and F2: SECTOR Imager 6000 (model 1201) and SECTOR Imager 2400/2400A (models 1250/1251) T4.0 A, 250 V, 100–240 V~ SECTOR Imager 6000 (model 1200) T4.0 A, 250 V, 100/120 V~...

  • Page 52: Weee Compliance

    Scientific and Technical Support with inquiries about the regulatory compliance of MSD instrumentation. WEEE Compliance 8.3.1 For all inquiries regarding recycling of shipping materials, instrument disposal, and WEEE-related issues, please contact an MSD instrument service specialist at 301.947.2057 or instrumentservice@mesoscale.com. Appendix...

  • Page 53: Symbols And Labels

    Symbols and Labels Table 8:3 Symbols and labels Symbol/Label Description Consult accompanying documentation/written warning Device contains high voltages Pinch Hazard Warning Accessible fuse with rating Class 2 Laser Warning Electrostatic Sensitive Device Volts Amps Alternating Current Halt plate motion system European Compliance Mark Indicates that the device complies with applicable European Directives USB I/O Port Symbol and Reference Designation Camera Controller Serial I/O Port Symbol and Reference Designation...
  • Page 54 Technical Support...

  • Page 55: Technical Support

    Technical Support MSD provides excellent and timely support for all authorized users of SECTOR Imagers. We welcome and carefully consider all bug reports and suggestions for improvements to future versions. We will work with you to resolve any problems you may encounter.
  • Page 56 Technical Support...

This manual is also suitable for:

Sector image 6000

Table of Contents