Beckman Coulter CESI 8000 Preinstallation Manual
Beckman Coulter CESI 8000 Preinstallation Manual

Beckman Coulter CESI 8000 Preinstallation Manual

High performance separation system
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B11953AC
September 2015
Beckman Coulter, Inc.
250 S. Kraemer Blvd.
Brea, CA 92821 U.S.A.
Preinstallation Manual
CESI 8000
High Performance Separation
System
Preinstallation

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Summary of Contents for Beckman Coulter CESI 8000

  • Page 1 Preinstallation Manual CESI 8000 High Performance Separation System Preinstallation B11953AC September 2015 Beckman Coulter, Inc. 250 S. Kraemer Blvd. Brea, CA 92821 U.S.A.
  • Page 2 All rights reserved. Beckman Coulter, Inc. grants a limited non-exclusive license to the owner or operator of a CESI 8000 instrument to make a copy, solely for laboratory use, of any portion or all of the online help and electronic documents shipped with the CESI 8000 instrument.
  • Page 3: Sciex Separations

    AB SCIEX is expanding the power of these technologies by combining the nano and micro liquid chromatography expertise of our Eksigent solutions and the microscale separation expertise from Beckman Coulter Life Sciences, to create the business unit known as SCIEX Separations.
  • Page 4: Revision History

    This document applies to the latest software and firmware listed above, and any higher subsequent versions. When a subsequent software or firmware version affects the information in this document, a new issue will be released to the Beckman Coulter website. For updates, go to www.beckmancoulter.com download the latest version of the manual.
  • Page 5: Safety, Notices And Labels

    Safety, Notices and Labels Overview A description of the symbols and labels that are used on the Beckman Coulter CESI 8000 High Performance Separation System, or that are shown in this manual, can be found in this section. Do not attempt to perform any procedure before carefully reading all instructions. If in doubt as to how to proceed in any situation, contact your Beckman Coulter Representative.
  • Page 6: Instrument Safety Precautions

    • This equipment is used in a manner other than specified. Operate the instrument as instructed in the Product Manuals. • You introduce software that is not authorized by Beckman Coulter into your computer. Only operate your system’s computer with software authorized by Beckman Coulter.
  • Page 7: Moving Parts Or Sharp Objects

    Safety, Notices and Labels Moving Parts or Sharp Objects concerning the product. If you purchased this product from a third party and would like further information concerning this topic, contact your Beckman Coulter Representative. Moving Parts or Sharp Objects WARNING Risk of personal injury.
  • Page 8: Sharp Object Label

    The CESI 8000 instrument is situated on the mobile cart. The OptiMS cartridge spray tip (also known as the consumable) on the CESI 8000 instrument has to be in very close proximity to a Mass Spec when the system is used. To avoid damage to the OptiMS consumable, remove it from the MS adapter before adjusting the height or moving the cart.
  • Page 9: China Rohs Environmental Label

    Other Instrument Labels This section provides information for some labels and symbols appearing on the CESI 8000 instrument housing. These labels and symbols may be associated with user-serviceable procedures. Individual hazards associated with a specific procedure in this manual may use these labels and symbols, and are included in Warnings or Cautions within the procedures for that task.
  • Page 10: Ce Mark Label

    Australian and New Zealand markets. CSA Mark Label The CSA symbol on the CESI 8000 instrument indicates that the instrument has been certified by a Nationally Recognized Testing laboratory (NRTL) to applicable Laboratory Equipment Safety Standards for the United States and Canada.
  • Page 11: 综述

    综述 用于 Beckman Coulter CESI 8000 高性能分离系统或在本手册中显示的符号和标签的描述可 在本节中找到。 仔细阅读所有说明之前,请勿尝试执行任何操作。在任何情况下如果不知如何处理,请 与您的 Beckman Coulter 代表联系。 Beckman Coulter, Inc. 强烈要求其客户和员工遵守所有国家健康和安全标准,如防护的使 用。此标准包括但不限于下列事项:操作或维护本仪器或任何其他实验室自动仪器时, 请佩戴防护眼镜、手套和合适的实验室装备。 警告 如果设备的使用未能按照 Beckman Coulter 公司所指定的方式进行,该设备所 具备的保护性能可能受损。 警告、注意、重要事项以及注释的提示 本文档中的所有警告与注意都包含感叹号,设在三角形中。 感叹号符号是国际通用符号,用于提示在安装、使用、维护和维修前应阅读并理解所有 的安全说明。 警告 “警告”指可能的有害情况,若未加以避免,则会导致死亡或严重伤害。也可用 它来说明有可能出现可能导致错误诊断的错误数据。还可用它来说明仪器严重 损坏的可能性。 注意 “小心”是指如果未能避免可能导致轻微或中度伤害的潜在危险情况。可用于警 示不安全操作。可能用于说明有可能出现可能导致错误诊断的错误数据。 重要 用于对正在执行的步骤或程序进行有价值的备注。遵循“重要事项”中的建议有助于改善某 件设备或某个程序的性能。 注释...
  • Page 12: 仪器安全防护措施

    以下情况会破坏系统完整性并可能导致操作失败: • 未按操作要求使用本设备。请按照“产品手册”中说明的方式操作仪器。 • 在计算机中安装了未经 Beckman Coulter 授权的软件。 请在系统的计算机上 仅运行 Beckman Coulter 授权的软件。 • 安装的软件并非是具有原始版权的版本。请仅使用具有原始版权的软件, 以防止病毒感染。 注意 如果是从 Beckman Coulter 或 Beckman Coulter 授权分销商之外的另一方购买的 本产品, 同时目前也不在 Beckman Coulter 服务维护协议的范围内, 则 Beckman Coulter 不能担保该产品具有最新的强制性工艺修订, 也不能担保用户可获得有 关该产品的最新信息公告。如果您从第三方购买了此产品且想要了解这方面的 更多信息,请联系您的 Beckman Coulter 代表。 B11953AC...
  • Page 13: 活动部件或尖锐物

    活动部件或尖锐物 活动部件或尖锐物 警告 可能导致人身伤害。为避免遭到活动部件的伤害,请遵守以下操作提示: • 仪器运转时,请勿调换实验室器具、试剂或工具。 • 不得手动限制仪器上任何组件的运动。 • 保持仪器工作区清空,以防限制组件的活动。 电气安全 为避免电气相关的伤害和财产损失,使用前请正确检查所有的电气设备并及时报告所有 的电气缺陷。维修设备时如需拆除盖板或面板,请联系 Beckman Coulter 代表。 安全符号和标签 高压电击危险符号 此符号表示存在高电压和电击危险,并且操作员进入此区域时应小心操作。 144557-AB 尖锐物标签 此符号表示存在尖锐物,并且操作员进入此区域时应小心操作。 B11953AC xiii...
  • Page 14 RoHS 通知 流动车警告标签 移动车时或调整车的高度时,在 CESI 8000 流动车上会看到用户警告标签。 CESI 8000 仪器位于流动车上。使用系统时,CESI 8000 仪器上的 OptiMS 墨盒喷嘴 (也称作 消耗品)必须十分接近质谱仪。为了避免损坏 OptiMS 消耗品,在调整高度或移动车之 前,请将它从 MS 适配器上移除。 RoHS 通知 这些标签和材料声明表 (有害物质的名称和含量表)必须符合中华人民共和国电子行业 标准 SJ/T11364-2006 《电子信息产品污染控制标识要求》中的要求。 中国 RoHS 警告标签 该标签表示电子信息产品包含某些有毒或有害物质。中间数字为环保使用期限 (EFUP) 日 期,表示产品可运行的年数。EFUP 到期后,必须立即回收产品。环形箭头表示产品可回 收。标签或产品上的日期代码为制造日期。 中国 RoHS 环保标签...
  • Page 15 本节提供了出现在 CESI 8000 仪器外罩上的一些标签和符号信息。这些标签和符号可能与 用户自行执行的操作过程有关。本手册中,与特定操作过程相关的各种风险可能使用这 些标签和符号,详见该任务操作过程中的“警告”或“注意”部分。 环保标签 (WEEE) 按照欧盟报废电子电气设备 (WEEE) 指令要求,产品上必须标有带叉的有轮垃圾桶符号。 产品上出现该标志,说明: • 该设备是在 2005 年 8 月 13 日以后投放欧洲市场的,并且 • 设备将不通过欧盟的任何成员国的市政废物收集系统进行处置。 对于 WEEE 指令规定的产品,请联系您的经销商或当地的 Beckman Coulter 办公室,了解有 关合理净化和收回程序的详细信息,这有助于您正确收集、处理、复原、回收和安全处 置设备。 CE 标志标签 CE 符号是个符合性标记, 说明 CESI 8000 仪器符合欧洲经济区 (EEA) 内适用的欧洲符合性指 令要求。 B11953AC...
  • Page 16 其他仪器标签 C-Tick 标志标签 CESI 8000 仪器上的 C-Tick 符号是个识别标志,说明了该仪器符合澳大利亚和新西兰市场 上适用的电磁兼容性 (EMC) 要求。 CSA 标识标签 CESI 8000 仪器上的 CSA 符号表明,该仪器被国家认可测试实验室 (NRTL) 认证为符合适用 的美国和加拿大实验室设备安全标准。 B11953AC...
  • Page 17: Table Of Contents

    Contents SCIEX Separations, iii CE and LC taken to the next level - consolidating expertise for more powerful separations, iii SCIEX Separations. Be part of it., iii Revision History, iv Safety, Notices and Labels, v Overview, v Alerts for Warning, Caution, Important, and Note, v Instrument Safety Precautions, vi...
  • Page 18 Ventilation Requirements, 2-6 Electrical Requirements, 2-7 Additional Electrical Requirements, 2-7 CHAPTER 3: Preparing CESI 8000 for Setup, 3-1 Upon Receiving the CESI 8000 System, 3-1 Moving the Boxes, 3-1 Confirming the Setup, 3-1 Safety Considerations During Setup, 3-2 Setup, 3-2...
  • Page 19 Contents CHAPTER 4: CESI 8000 System Training, 4-1 Pre-Training Requirements, 4-1 Additional Training, 4-1 Beckman Coulter, Inc. Warranty and Returned Goods Requirements...
  • Page 20 Illustrations Illustrations CESI 8000 Instrument Dimensions, 2-3 CESI 8000 Mobile Cart Dimensions, 2-4 Typical CESI 8000 System Setup, 2-6 Remove 1-inch Adapter Ring, 3-2 Ion Sweep Cone (remove if in place), 3-3...
  • Page 21 Tables Tables CESI 8000 Site Requirements, 2-1 CESI 8000 Instrument Specifications, 2-2 CESI 8000 Mobile Cart Specifications, 2-4 CESI 8000 Computer System Specifications, 2-5 CESI 8000 Electrical Components and Requirements, 2-7...
  • Page 22 Tables xxii...
  • Page 23: Overview

    Preparing CESI 8000 for Setup • CESI 8000 System Training • IMPORTANT The “Customer Preinstallation and Sign-off Sheet” on the next page must be completed and sent to your CESI 8000 representative before installation of the CESI 8000 system can begin. B11953AC xxiii...
  • Page 24: Customer Preinstallation Checklist And Sign-Off Sheet

    Customer Preinstallation Checklist and Sign-off Sheet The following is a list of lab items that are required at the site before installation of the CESI 8000 system can occur. Use this checklist to verify that you have the lab items necessary to ensure a successful installation.
  • Page 25: Chapter 1: Preinstallation Requirements

    (CHAPTER 4, CESI 8000 System Training) CESI 8000 System Components The following is a list of the primary components shipped by Beckman Coulter for a CESI 8000 system. Use this list to check off the items as you receive them. System Components •...
  • Page 26: Technical Support

    Preparation Check List Technical Support If you encounter a problem that is not discussed in this guide, and you need technical support, contact your local dealer, the provider of this product, or contact Beckman Coulter directly by using the information below. NOTE Whenever you call your local dealer or Beckman Coulter, be sure to have your instrument serial number and software version number available.
  • Page 27: Chapter 2: Site Requirements And Specifications

    Space and Ventilation Requirements. • The mobile cart holding the CESI 8000 instrument and computer system is level and stable so that normal operations of the instrument and computer does not cause the cart to shift, jerk, or sway (refer to CESI 8000 Mobile Cart).
  • Page 28: Cesi 8000 System Specifications

    Table 2.2 presents system specifications and requirements for the CESI 8000 High Performance Separation System. The CESI 8000 instrument should be placed on top of the CESI 8000 Mobile Cart. The dimensions for the CESI 8000 instrument are also shown in Figure 2.1.
  • Page 29: Cesi 8000 Mobile Cart

    CESI 8000 Mobile Cart The CESI 8000 Mobile Cart is designed to provide the tabletop space where the CESI 8000 instrument can be placed. The cart will also hold all of the hardware components that are shipped as the CESI 8000 Computer System.
  • Page 30: Cesi 8000 Computer System

    — 136.0 kg (300 lb) Figure 2.2 CESI 8000 Mobile Cart Dimensions CESI 8000 Computer System The CESI 8000 Computer System is made up of the following four components: • IBM Controller (small form factor PC) • 22-inch Monitor • Keyboard •...
  • Page 31: Mass Spec Software Requirements

    The specifications for the CESI 8000 Computer System are shown in Table 2.4. The CESI 8000 Mobile Cart is designed to hold the CESI 8000 Computer System (listed above). Table 2.4 CESI 8000 Computer System Specifications Specification Description Computer Requirements •...
  • Page 32: Space And Ventilation Requirements

    Space and Ventilation Requirements Space and Ventilation Requirements The CESI 8000 High Performance Separation System must be installed on a level and stable working surface capable of supporting 226.7 kg to 272.1 kg (500 to 600 lbs) without bowing by more than 6.35 mm (1/8 in.)
  • Page 33: Electrical Requirements

    NOTE There is one universal power strip bolted to the CESI 8000 Cart tabletop that will supply power to the CESI 8000 instrument, the cart, the controller (PC), and the monitor. The cart has one external cord that is used to provide power to the tabletop universal power strip.
  • Page 34 Site Requirements and Specifications Electrical Requirements B11953AC...
  • Page 35: Chapter 3: Preparing Cesi 8000 For Setup

    Customer Technical Support Center to schedule an on-site appointment with a Field Service Engineer. When the Field Service Engineer arrives, he or she will unpack the components from the boxes, and set up the CESI 8000 High Performance Separation System in the desired location. B11953AC...
  • Page 36: Safety Considerations During Setup

    When the Field Services Representative arrives to unbox and set up your unit, ensure the following precaution is observed: CAUTION A minimum of four people is needed to lift the CESI 8000 instrument. Failure to do so could result in bodily injury and/or damage to the instrument. MS Setup If you are using a Thermo Scientific MS, prior to installing the NanoSpray II source ensure that the 1-inch adapter ring for dynamic nano spray is not installed.
  • Page 37: Ion Sweep Cone

    Preparing CESI 8000 for Setup Upon Receiving the CESI 8000 System CAUTION The Ion Sweep Cone may be hot. Care must be taken when manipulating this part. Figure 3.2 Ion Sweep Cone (remove if in place) 1. Gas inlet B11953AC...
  • Page 38 Preparing CESI 8000 for Setup Upon Receiving the CESI 8000 System B11953AC...
  • Page 39 CHAPTER 4 CESI 8000 System Training Pre-Training Requirements After the system has been installed, a Beckman Coulter Field Engineer will train up to two operators in basic CESI 8000 system operation. IMPORTANT The CESI 8000 customers (i.e., up to two operators) must be Mass Spectrometer trained and willing to operate the Mass Spectrometer during installation.
  • Page 40 CESI 8000 System Training Additional Training B11953AC...
  • Page 41 Requirements, Instrument, Instrument Specifications, Preinstallation Checklist, xxiii Mobile Cart, Preinstallation Requirements, xxiii Requirements, Preparing CESI 8000 for Setup, xxiii Site Requirements, Preparing the Site, Space Requirements, Pre-Training Requirements, System Components, Technical Support, Training, Ventilation Requirements, Receiving the CESI 8000 System,...
  • Page 42: Setup

    Safety Notices, Safety considerations during setup, Safety Notice caution, electrical safety, important, instrument safety precautions, moving parts, note, sharp objects, warning, safety notice electrical safety, Setup Confirmation, Safety considerations, Site Preparations, Site Requirements, Site Requirements and Specifications, xxiii Space Requirements, Specifications, System Components, System Specifications,...
  • Page 43 Beckman Coulter, Inc. Warranty and Returned Goods Requirements All standard Beckman Coulter, Inc. policies governing returned goods apply to this product. Subject to the exceptions and upon the conditions stated below, the Company warrants that the products sold under this sales agreement shall be free from defects in workmanship and materials for one...
  • Page 44 Performance characteristics and specifications are only warranted when Beckman Coulter replacement parts are used. Except as provided in writing signed by an officer to Beckman Coulter, Inc., this system and any related documentation are provided “as is” without warranty of any kind, expressed or implied, including that the system is “error free.”...
  • Page 46 Related Documents CESI 8000 User Manual CESI 8000 System CESI 8000 Software Validation PN B11949 Administration Pack System Overview • PN B11951 PN B11952 Integrating CESI 8000 with • • System Administration System Overview • Mass Spectrometers Overview Technical Description •...

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