PermkinElmer NexION 300 ICP-MS Manual

PermkinElmer NexION 300 ICP-MS Manual

Icp-mass spectrometry

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NexION 300 ICP-MS
Introduction
PerkinElmer
ICP-MS instruments are complete systems
®
with the exception of the following items which must
be provided by the customer: electrical power, exhaust
vents, argon gas supplies with approved regulator, cell
gas supply, and coolant system.

Required Environmental Conditions

The laboratory environment in which the NexION
ICP-MS instrument is installed should meet the following
conditions:
• The room temperature should be between 15 and
30 ˚C (59-86 ˚F) with a maximum rate of change of
3 ˚C (5 ˚F) per hour.
• The relative humidity should be between 20 and
80%, non-condensing. For optimum performance,
the room temperature should be controlled at
20 ±2 ˚C (68 ±3.6 ˚F), and the relative humidity
should be between 35 and 50%.
• The instrument is certified for operation at elevations up
to 2000 meters (6562 ft.) above sea level.
In addition, the instrument should be located in an
area that is:
- Indoors
- Free of smoke, dust and corrosive fumes
- Not prone to excessive vibration
- Out of direct sunlight
- Away from heat radiators
300
®
In order to minimize contamination problems, a
dust-free environment is necessary. For ultra-trace
techniques, environmental contamination becomes a
limiting factor in the analysis. To quantitate ubiquitous
elements such as Fe, Ca, K, Na, etc. below 1 ppb (µg/L),
a class 1000 environment is necessary for sample
preparation and analysis. This is not an indication of
the performance limitations of the instrument, but
a recommendation for an ultra-clean environment.
The NexION 300 ICP-MS can be installed into a mobile
laboratory if vibration is isolated.
P R E P A R I N G Y O U R L A B
ICP-Mass Spectrometry
Preparation Checklist
• Environmental conditions
• Electrical requirements
• Space requirements
• Exhaust ventilation
• Coolant requirements
• Argon gas requirements
• Cell gas requirements

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Summary of Contents for PermkinElmer NexION 300 ICP-MS

  • Page 1 80%, non-condensing. For optimum performance, a recommendation for an ultra-clean environment. the room temperature should be controlled at 20 ±2 ˚C (68 ±3.6 ˚F), and the relative humidity The NexION 300 ICP-MS can be installed into a mobile should be between 35 and 50%. laboratory if vibration is isolated. • The instrument is certified for operation at elevations up to 2000 meters (6562 ft.) above sea level.
  • Page 2 The diameter of the Dispose of waste correctly. hose must remain at least 25 mm (1 in.) ID. • Do not allow smoking in the work area. Smoking is a source of significant contamination and also a potential The NexION 300 ICP-MS is designed to operate on a bench route for ingesting harmful chemicals. 66-91 cm high (26-36 in. high). PerkinElmer offers a bench designed for the NexION 300 ICP-MS (Part No. N8141230). • Do not store, handle, or consume food in the work area.
  • Page 3 Dimensions will vary by model Printer Dimensions will vary by model *Width including the shipping handles is 141 cm (56.5 in.) 122.5 cm (49 in.) The NexION 300 ICP-MS can be positioned in either a linear or an L-shaped configuration. In the L-shaped configuration, Figure 1. Dimensions of NexION 300 ICP-MS spectrometer. the computer and printer are positioned on one leg of the L. The instrument and an accessory table make up the other System Layout leg. A recommended workstation layout is shown in Figure 2.
  • Page 4 Drain Vessels Safe Handling of Gas Cylinders NOTE: The permanent installation of gas supplies is the responsibility of the A drain vessel is supplied with the NexION 300 ICP-MS. The user and should conform to local safety and building codes. vessel is made of HDPE (high density polyethylene) and is used to collect the effluent from the ICP sample-introduction • Fasten all gas cylinders securely to an immovable bulkhead system. The NexION 300 ICP-MS also has a torch box drain or a permanent wall.
  • Page 5 Facilities Requirements Table 3 provides information on the gas and liquid services required for the NexION 300 ICP-MS. Tables 4 and 5 show the electrical supply requirements and approximate power consumption of the NexION 300 ICP-MS and its major accessories. Table 3. Gas and Liquid Services Required for the NexION 300 ICP-MS. Gases Operating pressure...
  • Page 6 Figure 6. Location of exhaust ports. Mains Connection The instrument is shipped with one 2.4 m (8 ft.) mains cord terminated by an IEC 60309 connector rated 30A by UL (North The NexION 300 ICP-MS has two separate exhaust ports. America) and 32A by VDE (International) for 250V as shown in Figure 5. Both of the NexION 300 ICP-MS exhaust ports are located on the top of the instrument (see Figure 6). The torch box exhaust port is located 46.5 cm (18.5 in.) from the right side of the instrument. The RF generator exhaust port is located 67.5 cm (27 in.) from the left side of the instrument. The torch box exhaust port exhausts the following: • Plasma heat and fumes • Vacuum pump exhaust – including cell gases on Universal...
  • Page 7 The torch box exhaust must be installed, but the RF generator least 1.4 meters (4 ft.) away from any heat-generating exhaust is optional (see note in Table 7*). sources such as the roughing pump or other instruments. Proper ventilation is critical for the heat exchanger – its The RF generator exhaust vent is used for the blower that ambient air temperature must never exceed 30 ˚C. cools the system power supplies and ICP generator. Venting System Recommendations We recommend using two 100-mm (4 in.) exhaust hoses The exhaust flow rate at the instrument (the ability to vent (for both the torch box exhaust vent and RF generator...
  • Page 8 NexION 300 ICP-MS instrument. The recirculator operating pressure should be 413 ±13 kPa Gaseous argon tanks do not require venting and consequently (60 ±2 psi). A coolant flow of at least 3.8 L/min (1.0 gpm)
  • Page 9 The NexION 300 ICP-MS is shipped with the regulator- A dedicated UHP helium cylinder is required; house helium to-cylinder fittings shown in Table 8. The cell gas cylinders supplies must not be used. The purity of any other cell gas, should use this type of fitting when ordered from your local must be ≥ 99.999% pure.

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