MSI Z270 GAMING M6 AC Instructions Manual page 36

M.2 slots with examples of various combination possibilities
2xM.2 PCIe SSDs + 4xSATA HDDs
PCIe
PCIe
1xM.2 PCIe SSD + 1xM.2 SATA SSD +
5xSATA HDDs
PCIe
SATA
1xM.2 PCIe SSD + 6xSATA HDDs
PCIe
36
Overview of Components
2xM.2 SATA SSDs + 4xSATA HDDs
SATA
SATA
1xM.2 PCIe SSD + 1xM.2 SATA SSD +
3xSATA HDDs
SATA
PCIe
1xM.2 PCIe SSD + 4xSATA HDDs
PCIe