HP Pavilion Slimline s5220f Supplementary Manual page 24

20 Lift the cage all the way out of the computer and set it
on its side.
21 Locate the cables connected to the hard disk drive.
8
22 Disconnect the cables from the drive:
— Removing and Replacing the Hard Disk Drive
537496-001
The plugs on the cables are keyed and can be
inserted only when aligned properly with the
connector on the drive.
In addition, some plugs have a latch that must be
pressed or squeezed to release the plug while pulling
it from the connector.
Plugs without a latch:
For a plug without a latch, pull the plug straight
out from the connector.
Plugs with a latch:
For a plug with a latch, press the latch in the
center of the plug, and then pull the plug from the
connector.