Shimadzu SIL-40C XR CL Manuals

Manuals and User Guides for Shimadzu SIL-40C XR CL. We have 2 Shimadzu SIL-40C XR CL manuals available for free PDF download: System Manual, Safety Manualline

Shimadzu SIL-40C XR CL System Manual (338 pages)

Brand: Shimadzu | Category: Laboratory Equipment | Size: 22 MB

Introduction
4
Instruction Manual Components
4
Operating Nexera CL System
7
Table of Contents
8
Overview
15
System Features
15
LC-40D XR CL, LC-40D X3 CL, or LC-40B X3 CL Solvent Delivery Unit
15
SIL-40C XR CL or SIL-40C X3 CL Autosampler
16
CTO-40C CL Column Oven
17
CL UV-VIS Detector
17
Optional Parts
17
Configuration List
20
Switching on the Power Supply and Opening the [Realtime Analysis] Window
24
Switching on the Instruments Power Supply
24
Logging in to Labsolutions and Opening the [Realtime Analysis] Window
26
Specifying Analytical Conditions
29
Editing Methods
29
Placing Mobile Phases and Autosampler Rinse Solutions
36
Placing Mobile Phase and Rinse Solution Bottles on the Reservoir Tray
36
Performing Auto-Purging
38
Manual Purging the Solvent Delivery Pump
40
Attaching the Column
43
Attaching Columns in the Column Oven
43
Warming up the System
46
Placing Samples
48
Preparing Sample Vials (or Sample Plates)
48
Placing Samples in the Autosampler
50
Performing a Single Run Analysis
54
Check List to Confirm before Starting Analysis
54
Performing a Single Run Analysis
55
Performing Postrun Analysis
57
Displaying and Printing Data Reports
61
Performing Realtime Batch (Sequence) Analysis
62
Analyzing Multiple Sets of Data Using Data Browser
65
Outputting Summary Reports
67
Stopping Analysis and Shutting off the Power Supply
69
Check List to Confirm after Analysis Is Finished
69
Purging Columns with a Column Storage Solution
69
Shutting down the Instruments
70
Setting up Startup for Next Use
72
Key Points for Analysis
72
Before Analysis
72
Precautions for Selecting and Handling Mobile Phase Solvents
78
Precautions When Replacing the Mobile Phase
78
Precautions for Selecting an Autosampler Rinse Solution
79
Using Buffer Solutions as a Mobile Phase
82
Application Operations
84
Startup and Shutdown Functions
84
Startup Function
84
Executing the Startup Process
84
Executing a Startup Process and Starting a Batch Analysis at a Specified Date/Time
86
Shutdown Function
89
Executing the Shutdown Function
89
Executing a Batch File with a Shutdown Function Specified in the File
91
Auto-Diagnostics (Pulsation Check) and Auto-Recovery
95
Auto-Diagnostics (Pulsation Check)
95
Auto-Recovery
95
Autosampler Functions
99
Pretreatment Functions
99
Cut off Loop Function
102
Low Dispersion Injection
103
Batch Action Functions
103
Using ACTO (Analytical Condition Transfer and Optimization) Functions
107
Concentration Gradient Start Adjustment Function
107
Method Migration Functions
109
Useful Data Analysis Functions
112
I-Peakfinder
112
Column Management
114
Column Management Workflow
115
Setup for Labsolutions
116
Column Registration and Replacement (Discard)
120
Analysis with Labsolutions
129
Viewing the Acquisition Log
132
Hardware Validation
136
Hardware Validation Overview
136
Hardware Validation Classifications
136
Timing for Hardware Validation
136
Periodic Inspections
136
Routine Inspections
137
Inspections During Maintenance
137
Precautions for Periodic Inspections
137
Parts Required for Periodic Inspections
137
Periodic Inspection of Solvent Delivery Pumps
141
Inspection Item
141
Testing Flowrate Accuracy
141
Periodic Inspection of Autosamplers
144
Inspection Item
144
Injection Volume Accuracy Test
144
Temperature Accuracy Test
145
Periodic Inspection of Plate Changers
148
Inspection Item
148
Checking Temperature Accuracy
148
Periodic Inspection of Column Ovens
151
Inspection Item
151
Testing the Temperature Adjustment Function
151
Periodic Inspection of UV Absorbance Detectors
154
Inspection Item
154
Wavelength Accuracy Test
154
Periodic Inspections of Systems
160
Inspection Item
161
Absorbance Linearity Test
161
Noise/Drift Test
163
Gradient Concentration Test (Gradient System)
166
Reproducibility Test
170
Injection Linearity Test
173
Carryover Test
173
Corrective Measures if Control Criteria Are Not Satisfied
175
Troubleshooting
175
Troubleshooting
176
Errors and Operating Problems
176
Resolving Common Troubleshooting Issues
177
Communication Fails
177
Solvent Flow Does Not Stabilize
178
Solvent Delivery Pressure Increases
179
Baseline Does Not Stabilize
182
Noise Appears in Baseline
183
Poor Area Value Reproducibility
185
Carryover Does Not Disappear
188
Troubleshooting
189
Hardware Status
189
Symptoms Presumably Due to an Error, Based on a Chromatogram
198
List of Error Messages
208
System Controller
208
Pump
213
Autosampler
217
Column Oven
246
UV Detector
253
Selecting Components
259
Selecting a System
259
System Installation Arrangement
260
System Tubing
262
Ultra High-Speed Analysis
264
Selecting a Mixer
265
Selecting the Cell
266
Installation
267
Installing the System
267
Removing Items Used to Secure the System During Shipping
267
Installing the Autosampler
268
Installing the Solvent Delivery Pump
271
LC-40D X3 CL, or LC-40B X3 CL)
271
Installing the Detectors (SPD-40 CL)
272
Installing the Degassing Unit (DGU-405 CL)
273
Installing the Reservoir Tray
274
Installing the Column Oven (CTO-40C CL)
275
Installing Other Instruments
276
Cable Connections
277
Connecting the Power Cord
277
Connecting Optical Cables
277
Connecting a Degassing Unit (DGU-405 CL) to the Solvent Delivery Pump
281
Tubing Connections
284
Installing Tubes and Joints for Draining Leakage
286
Connecting Low-Pressure Flow Channel Tubing
295
Connecting Tubing for High-Pressure Flow Channels (Connection Methods)
308
Connecting Tubing for High-Pressure Flow Channels (Gradient Systems)
314
Connecting Tubing for High-Pressure Flow Channels (Isocratic Systems)
318
Checking Computer and System Controller Connections
319
Setting the Computer IP Address
320
Specifying Computer Browser Settings
322
Specifying System Controller Settings
324
Other Installation Processes
326
Connecting to Labsolutions
326
Connecting the Computer to the System Controller
326
Installing Optional Column Management Functionality
327
Addendum
330
Mobile Phase Properties
330
Index
337

Shimadzu SIL-40C XR CL Safety Manualline (42 pages)

Liquid Chromatograph

Brand: Shimadzu | Category: Laboratory Equipment | Size: 3 MB

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